Design of NH-10 and NH-73 Byircmethod and their comparison with Aashto Method and Pcamethod

Nowadays, Environment Sustainability and effective use of natural resources is a great concern. To build hundreds of kilometres of roadway it involves huge amount of natural resources and we know that our natural resources are in very limited quantity. To save our limited resources any sustainable approach or any green technology or any method that can let us use our resources effectively is welcomed. One such approach for the sustainability of the environment is presented in this paper through the different pavement design approaches. In recent years, cement concrete pavements are being adopted in many new road projects in India in view of their longer service lives, lesser maintenance requirements and smoother riding surface. In this paper, National Highway-10 (Hisar and Dabwali) and National Highway-73 (Punchkula and Yamunanagar) is designed by three methods i.e. by IRC Method which is followed in India and by AASHTO method and PCA Method which are used in American countries. As the IRC method is partly based on the recommendations of AASHTO method and PCA method, it is required to compare the methods to know which is having more economical approach. Through this paper it is found that the IRC gives relatively less thickness as compared to other methods. By this finding we can say that in IRC method the quantity of materials required such as aggregate, bitumen etc.is less which in turn saves our natural resources and preserves our resources for future use. It is also found that the IRC method is more economical

Design of NH-10 and NH-73 Byircmethod and their comparison with Aashto Method and Pcamethod

33-38Nowadays, Environment Sustainability and effective use of natural resources is a great concern. To build hundreds of kilometres of roadway it involves huge amount of natural resources and we know that our natural resources are in very limited quantity. To save our limited resources any sustainable approach or any green technology or any method that can let us use our resources effectively is welcomed. One such approach for the sustainability of the environment is presented in this paper through the different pavement design approaches. In recent years, cement concrete pavements are being adopted in many new road projects in India in view of their longer service lives, lesser maintenance requirements and smoother riding surface. In this paper, National Highway-10 (Hisar and Dabwali) and National Highway-73 (Punchkula and Yamunanagar) is designed by three methods i.e. by IRC Method which is followed in India and by AASHTO method and PCA Method which are used in American countries. As the IRC method is partly based on the recommendations of AASHTO method and PCA method, it is required to compare the methods to know which is having more economical approach. Through this paper it is found that the IRC gives relatively less thickness as compared to other methods. By this finding we can say that in IRC method the quantity of materials required such as aggregate, bitumen etc.is less which in turn saves our natural resources and preserves our resources for future use. It is also found that the IRC method is more economical

Urbanisation Effect on Hydrological Response: A Case Study of Asan River Watershed, India

Human being keeps on modifying the environment especially land use/land cover (LULC), in pursuance of excel, comfort and development. The subsequent impact of urbanization to the environment, especially land cover change, now occurs on scales that significantly affect hydrologic variations. The altering environment makes it necessary to understand and quantify various hydrological components for efficient water resource management. Therefore, in the present study, an attempt was  made to study the impact of LULC change on runoff generation potential. Asan River watershed, which lies in Dehradun, capital of newly created Uttarakhand State, India, is selected as study region. A huge industrialization is been taken place within this watershed immediately after declaration of state in year 2000. Initially, LULC change detection analysis was carried out by simple LULC class area difference between two years under consideration i.e. 2000 and 2010. The hydrological simulation using variable infiltration capacity macro-scale hydrological model depicted increase in runoff after urbanization took place. Keywords: Land use land cover change, Urbanization, Impact assessment, hydrological modeling, variable infiltration capacity model, runoff potentia

A Cross-Cultural Comparison of Business Complaint Management Expectations

This paper is in closed access until 9th Dec 2016.Copyright © Taylor and Francis Group, LLC. This study explores the complaint management expectations of 72 British and 74 German organizational buyers using automated online means-end laddering and a Hierarchical Value Map presentation. It conceptualizes the links between expected complaint resolution attributes by the buyer (i.e., means) and the buyer's value perceptions (i.e., ends). Unlike previous research, we highlight similarities and differences in the drivers behind and attributes of complaint management expectations across two countries (Germany and the United Kingdom). Even in countries appearing to be similar economically and culturally, we find differences in the desired attributes. British buyers, for example, emphasize softer complaint resolution attributes compared to Germans. Our study is the first to present a model of complaint management expectations incorporating the role of culture, and it provides managerial directions on standardization and adaption of complaint resolution attributes. Furthermore, it evaluates justice dimensions (especially interactional justice) and their impact on perceptions of complaint management

Compound Semiconductor Materials and Devices

Contains table of contents for Part I, table of contents for Section 1, reports on fourteen research projects and a list of publications.Defense Advanced Research Projects Agency/National Center for Integrated Photonics TechnologyFannie and John Hertz Foundation Graduate FellowshipJoint Services Electronics Program Grant DAAH04-95-1-0038National Science Foundation Graduate FellowshipNTT CorporationNational Science FoundationU.S. Navy - Office of Naval ResearchToshiba CorporationAT&T Bell Laboratories Graduate Fellowshi

Compound Semiconductor Materials and Devices

Contains table of contents for Part I, table of contents for Section 1, an introduction, reports on fourteen research projects and a list of publications.Defense Advanced Research Projects Agency/National Center for Integrated Photonics TechnologyJoint Services Electronics Program Grant DAAH04-95-1-0038MIT Lincoln LaboratoryNational Science Foundation Graduate FellowshipU.S. Navy - Office of Naval ResearchAT&T Bell Laboratories FellowshipU.S. Army - Ft. MeadeNTT CorporationNational Science FoundationLockheed-Martin Corporatio

Population Health Metrics Research Consortium gold standard verbal autopsy validation study: design, implementation, and development of analysis datasets

Background: Verbal autopsy methods are critically important for evaluating the leading causes of death in populations without adequate vital registration systems. With a myriad of analytical and data collection approaches, it is essential to create a high quality validation dataset from different populations to evaluate comparative method performance and make recommendations for future verbal autopsy implementation. This study was undertaken to compile a set of strictly defined gold standard deaths for which verbal autopsies were collected to validate the accuracy of different methods of verbal autopsy cause of death assignment.Methods: Data collection was implemented in six sites in four countries: Andhra Pradesh, India; Bohol, Philippines; Dar es Salaam, Tanzania; Mexico City, Mexico; Pemba Island, Tanzania; and Uttar Pradesh, India. The Population Health Metrics Research Consortium (PHMRC) developed stringent diagnostic criteria including laboratory, pathology, and medical imaging findings to identify gold standard deaths in health facilities as well as an enhanced verbal autopsy instrument based on World Health Organization (WHO) standards. A cause list was constructed based on the WHO Global Burden of Disease estimates of the leading causes of death, potential to identify unique signs and symptoms, and the likely existence of sufficient medical technology to ascertain gold standard cases. Blinded verbal autopsies were collected on all gold standard deaths.Results: Over 12,000 verbal autopsies on deaths with gold standard diagnoses were collected (7,836 adults, 2,075 children, 1,629 neonates, and 1,002 stillbirths). Difficulties in finding sufficient cases to meet gold standard criteria as well as problems with misclassification for certain causes meant that the target list of causes for analysis was reduced to 34 for adults, 21 for children, and 10 for neonates, excluding stillbirths. To ensure strict independence for the validation of methods and assessment of comparative performance, 500 test-train datasets were created from the universe of cases, covering a range of cause-specific compositions.Conclusions: This unique, robust validation dataset will allow scholars to evaluate the performance of different verbal autopsy analytic methods as well as instrument design. This dataset can be used to inform the implementation of verbal autopsies to more reliably ascertain cause of death in national health information systems

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.