Correlation of CORADS scoring with Psychiatric Co-morbidities in acute phase of COVID infection: A cross—sectional study

Background: There is a mutual relationship between COVID infection and mental illness. There is increase in the overall prevalence of psychiatric conditions in this pandemic. Yet, there is dearth in the literature on the relation between psychiatric morbidity and severity of COVID (assessed by CORADS score). Hence, we aimed to assess the various psychiatric conditions seen in the COVID patients, and the association of various factors with the CORADS severity score. Materials and Methods: It is a cross-sectional observational study conducted in stable COVID patients who were admitted in the hospital and are referred to psychiatric department for consultation during February, 2021 to April, 2021. After confirmation of COVID-19 through RTPCR, HRCT was done for CORADS scoring and a detail neuropsychological evaluation was conducted in these patients. Results: Among 100 responses, 67 patients were analyzed in detail. On Kruskal Wallis test, there was statistically significant association between CORADS score and age of the individual, history of personality traits and anxiety (p-value 0.001, 0.049 & 0.040 respectively). Around 43% of the sample were diagnosed with organic mood disorders, following with anxiety distress and cognitive disorders were more prevalent. Age -wise distribution of sample shows that anxiety was more seen in the individuals above 30 years of age. Conclusion: With the background of the upcoming mental health pandemic post COVID, it is the duty of the treating doctor to screen a patient diagnosed with COVID for comorbid psychiatric illnesses. This will help the patients to alleviate the symptoms and improve their functional outcome

A Snapshot of the Emerging Tomato Genome Sequence

The genome of tomato (Solanum lycopersicum L.) is being sequenced by an international consortium of 10 countries (Korea, China, the United Kingdom, India, the Netherlands, France, Japan, Spain, Italy, and the United States) as part of the larger \u201cInternational Solanaceae Genome Project (SOL): Systems Approach to Diversity and Adaptation\u201d initiative. The tomato genome sequencing project uses an ordered bacterial artificial chromosome (BAC) approach to generate a high-quality tomato euchromatic genome sequence for use as a reference genome for the Solanaceae and euasterids. Sequence is deposited at GenBank and at the SOL Genomics Network (SGN). Currently, there are around 1000 BACs finished or in progress, representing more than a third of the projected euchromatic portion of the genome. An annotation effort is also underway by the International Tomato Annotation Group. The expected number of genes in the euchromatin is 3c40,000, based on an estimate from a preliminary annotation of 11% of finished sequence. Here, we present this first snapshot of the emerging tomato genome and its annotation, a short comparison with potato (Solanum tuberosum L.) sequence data, and the tools available for the researchers to exploit this new resource are also presented. In the future, whole-genome shotgun techniques will be combined with the BAC-by-BAC approach to cover the entire tomato genome. The high-quality reference euchromatic tomato sequence is expected to be near completion by 2010