A HYBRID CLOUD APPROACH FOR SECURE APPROVED DEDUPLICATION

Information Deduplication is one of imperative information pressure systems for wiping out copy duplicates of rehashing information, and has been generally utilized as a part of distributed storage to decrease the measure of storage room and spare data transmission. To secure the secrecy of touchy information while supporting Deduplication, the concurrent encryption system has been proposed to scramble the information before outsourcing. To better ensure information security, this methodology makes the main endeavor to formally address the issue of approved information Deduplication. Unique in relation to customary Deduplication frameworks, the differential benefits of clients are further considered in copy check other than the information itself. It likewise exhibit a few new Deduplication developments supporting approved copy check in a half and half cloud engineering. Security examination exhibits that our plan is secure as far as the definitions indicated in the proposed security model. As a proof of idea, we actualize a model of proposed approved copy check plan and direct testbed tests utilizing model. It demonstrates that proposed approved copy check plan brings about insignificant overhead contrasted with typical operations

Aggressiveness of Ralstonia solanacearum isolates on Tomato

Bacterial wilt caused by Ralstonia solanacearum is the world’s most economically important destructive disease of crop plants. Fifty seven isolates of R. solanacearum causing wilt on different host plants were collected from different agro climatic zones of India of which 54 isolates were confirmed as race-1, biovar-3 and 3 isolates as race-1, biovar-3B based on morphological, physiological, biochemical and pathogenicity studies. All the isolates were authenticated as Ralstonia solanacearum by using two sets of primers (OLI1 & Y2 and Y1 & Y2). Serological identity of the isolates was done by using diagnostic kit obtained from International Potato Research Center, Lima, Peru and single chain variable fragment antibody specific to Ralstonia solanacearum. Fifty seven isolates of R. solanacearum were inoculated on tomato (Solanum Lycopersicum L) cv. Avinash-II under artificial conditions at bacterial concentration of 5x108 cfu/ml to test its aggressiveness; the results obtained are discussed in this paper

Management of type 2 diabetes mellitus: insights into prescribing trends

Background: Recently, management of type 2 diabetes mellitus (T2DM) has changed with advent of novel agents like DPP4i, SGLT2i and GLP-1 agonist. Of these, DPP4i have emerged as promising agents as monotherapy and as an add-on to metformin for improved glycaemic control.  This survey was planned to explore current prescribing trends of physicians of India for the management of T2DM.Methods: This was a prospective, cross sectional, questionnaire-based survey of physicians and endocrinologist across different geographic areas in India. A survey questionnaire consisting of 10 questions related to management of T2DM in real-world clinical settings was prepared, validated in a small group of physicians and then administered to physicians and endocrinologists.Results: Responses from 502 physicians were received. About 60% physicians prefer DPP4i as first add-on to metformin followed by sulfonylurea (SU) (30%). Amongst DPP4i, vildagliptin and sitagliptin were preferred by 48% and 28% physicians respectively as first add-on to metformin. For patients uncontrolled on metformin + SU therapy, 54 % physicians prefer DPP4i as second add-on. Vildagliptin is perceived to have the better efficacy and safety data, as suggested by 40% and 43% physicians respectively. Large number of physicians (48%) were hesitant to prescribe teneligliptin due to insufficient data. SGLT2 inhibitors are preferred as third add-on by 44% physicians.Conclusions: DPP4i are being increasingly preferred by physician as an add-on to metformin. Among DPP4i, the survey revealed that vildagliptin is the most preferred DPP4i as an add-on to metformin possibly owing to its established safety and efficacy data

A prospective study indicating that fractional excretion of sodium is a good marker for fluid loss

Background: Pre-renal failure, a reversible form of acute renal failure (ARF), accounts for 60-70% of all cases of ARF. To study the factors affecting fractional excretion of sodium (FENa) in patients with pre-renal failure.Methods: The study involved patients with pre-renal failure, admitted in a multi-speciality hospital in south India for a period of two years. The demographic and clinical data were collected using a standard pro forma. The correlation between FENa and factors such as age, diabetes mellitus, fluid loss, fever, urine output and creatinine of pre-renal failure were statistically evaluated.Results: The prospective study involved 24 patients diagnosed as pre-renal failure with a mean age of 52.75±18.78. The subjects included 14 males and 10 females, with a median FENa of 0.55 (0.10-0.90). A moderate negative correlation was observed between FENa and fluid loss in pre-renal failure patients (r -0.646, P=0.0007).Conclusions: The level of FENa may assist in estimating fluid loss in patients with pre-renal failure

Is Endophytic Colonization of Host Plants a Method of Alleviating Drought Stress?: Conceptualizing the Hidden World of Endophytes

In the wake of changing climatic conditions, plants are frequently exposed to a wide range of biotic and abiotic stresses at various stages of their development, all of which negatively affect their growth, development, and productivity. Drought is one of the most devastating abiotic stresses for most cultivated crops, particularly in arid and semiarid environments. Conventional breeding and biotechnological approaches are used to generate drought-tolerant crop plants. However, these techniques are costly and time-consuming. Plant-colonizing microbes, notably, endophytic fungi, have received increasing attention in recent years since they can boost plant growth and yield and can strengthen plant responses to abiotic stress. In this review, we describe these microorganisms and their relationship with host plants, summarize the current knowledge on how they “reprogram” the plants to promote their growth, productivity, and drought tolerance, and explain why they are promising agents in modern agriculture

Clinical profile of leptospirosis with focus on inflammatory biomarkers

Background: In the last few decades leptospirosis has re-emerged and is on the rise. Infectious diseases like malaria, dengue, infective hepatitis which simulate leptospirosis being rampant, so there is a need to know the clinical profile and biomarkers of leptospirosis. Study aimed to understand the clinical profile, laboratory findings and complications of leptospirosis with focus on inflammatory biomarkers.Methods: All consecutive inpatients of J.S.S medical college hospital with clinical suspicion of leptospirosis were screened for IgM anti-leptospiral antibody. Twenty-five patients who were positive for IgM antileptospiral antibodies were considered as cases and twenty-five patients who were admitted for fever other than leptospirosis were taken as controls and subjected to detailed history, clinical examination, investigations and followed up till discharge or death.Results: The age group commonly involved was 18-55 years (84%). Most of the patients were males (76%), with occupation involving outdoor activity (66%). Common symptoms were fever (100%), musculoskeletal pain (92%), headache (80%) and jaundice (64%). Less commonly seen were respiratory symptoms (36%), bleeding (24%), and gastrointestinal symptoms (16%). Important signs seen were conjunctival suffusion, hepatomegaly, splenomegaly and hypotension. Hyperbilirubinemia was predominantly of conjugated type and elevation of transaminases and alkaline phosphatase were mild to moderate. Mean bilirubin was 4.67mg/dl, Mean SGOT and SGPT were 99.23U/L and 96.97U/L respectively. ARF was seen in 48% and six of them needed haemodialysis. Thrombocytopenia was seen in 76% patients. 28% had multi-organ failure (MOF), 8% had aseptic meningitis, 8% had ARDS and 4% had GI haemorrhage.Conclusions: Musculoskeletal symptoms are most common next to fever. Conjunctival suffusion is a common finding. Liver and kidney are more commonly involved organs. MOF was significantly associated with mortality (p<.05). Thrombocytopenia was significantly related to clinical bleeding (p<.001). TNF-alpha and Interleukin-12 were significantly elevated in leptospirosis and may correlate with severity