Effect Of Oestradiol On Mouse Vaginal Epithelium

Oestradiol which induces the proliferation of the vaginal epithelium is used in the oestrogen replacement therapy for menopausal and postmenopausal disorders. The exact onset of induced cell proliferation and recovery to the controlled level has not been reported before. Hence this study was done in ovariectomised mice and the period of cellular response to ethinyl estradiol, a semisynthetic ester (0.025mg/kg) was recorded. The vaginal epithelium was studied for histological changes and incidence of mitotic figures. The onset of proliferation started at 4h after exposure and reached its maximum at 32h and declined gradually thereafter to reach the base level at 60h

Structure and Rheology of the Defect-gel States of Pure and Particle-dispersed Lyotropic Lamellar Phases

We present important new results from light-microscopy and rheometry on a moderately concentrated lyotropic smectic, with and without particulate additives. Shear-treatment aligns the phase rapidly, except for a striking network of oily-streak defects, which anneals out much more slowly. If spherical particles several microns in diameter are dispersed in the lamellar medium, part of the defect network persists under shear-treatment, its nodes anchored on the particles. The sample as prepared has substantial storage and loss moduli, both of which decrease steadily under shear-treatment. Adding particles enhances the moduli and retards their decay under shear. The data for the frequency-dependent storage modulus after various durations of shear-treatment can be scaled to collapse onto a single curve. The elasticity and dissipation in these samples thus arises mainly from the defect network, not directly from the smectic elasticity and hydrodynamics.Comment: 19 pages inclusive of 12 PostScript figures, uses revtex, psfrag and epsfig. Revised version, accepted for publication in Euro. Phys. J. B, with improved images of defect structure and theoretical estimates of network elasticity and scalin

Glutathione S-Transferase activity and total thiol status in chronic alcohol abusers before and 30 days after alcohol abstinence

Background: Glutathione S Transferase (GST) has been involved in detoxification process in the liver and its activity has been shown to be increased in alcohol abusers. In the current work we measured the GST activity, total thiol status, AST, ALT, and direct bilirubin in chronic alcohol abusers before and 30 days after alcohol abstinence and lifestyle modification. Methods: Serum and urine GST activity and total thiol status were determined using spectrophotometric methods and serum transaminases were determined using clinical chemistry analyzer. Results: We found,significant increase in serum and urine GST (p<0.001), AST (p<0.001), ALT (p<0.001), and decrease in total thiol status (p<0.001) in chronic alcohol abusers. GST activity significantly decreased (p<0.001) and total thiol status were improved significantly (p<0.001) 30 days after alcohol abstinence and lifestyle modification. Conclusion: This study provides preliminary data to suggest the role of GST as prognostic indicator of alcohol abstinence with possible trend towards an improvement in liver function

A Comparative Study Between Alcoholics of Koraga Community, Alcoholics of General Population and Healthy Controls for Antioxidant Markers and Liver Function Parameters

Objectives: It is well established that long-term alcohol consumption leads to liver cirrhosis and other related disorders. Sufficient work has been done on biochemical markers of liver damage and antioxidant status of chronic alcoholics in general population. In the current study chronic alcoholics from a community called Koraga are analysed for the same parameters in a view to assess the extent of liver damage as compared to healthy controls and other alcoholics. Methods: Serum and urine samples from Koraga alcoholics (n=28), general alcoholics (n=30) and healthy controls (n=31) were analysed for liver function parameters and antioxidant markers. Liver function parameters were determined by automated analyzer. Markers of antioxidant status were estimated spectrophotometrically. The data was analysed using SPSS version 16.0. Results: There was significant increase in serum AST, serum ALT, serum GST and urine GST in both general and Koraga alcoholics when compared to healthy controls (p<0.0001). Serum ALT, serum GST and urine GST activity was significantly higher in general alcoholics when compared to Koraga alcoholics (p<0.001). Serum and urine total thiol levels were significantly lower in general alcoholics when compared to healthy controls and Koraga alcoholics (p<0.0001). We have observed no difference in total thiols level between healthy controls and Koraga alcoholics, in fact, there was significant increase in urine total thiols level in Koraga alcoholics compared to healthy controls (p<0.001). On Pearson’s correlation serum AST, serum ALT correlated positively with serum and urine GST (p<0.0001) and negatively with serum total thiols (p<0.0001). Serum GST correlated negatively with serum total thiols (p<0.0001). Conclusion: Results of our study possibly indicate that the extent of alcohol induced liver damage in Koraga subjects is comparatively lower than general alcoholics, even though the alcohol consumption is found to be higher in them. There may be some mechanism that is rendering them resistant to alcoholic liver damage which needs to be explored through further studies at molecular level

Axillary Arch (Of Langer): Incidence, Innervation, Importance

The present study was planned to find out the incidence of accessory muscle arches in the axilla of 68 upper limb (38 right and 30 left) dissections. Langer’s arch was observed in one right limb out of the 68 limbs, total incidence was 1.47%. The arch extended from the latissimus dorsi to the fascia covering the biceps brachii. The incidence is low in South Indian population (Dravidians) compared to the various other populations reported in literature. A branch from the lateral cord of brachial plexus supplied it in contrast with the previous reports. The surgical significance of this muscle is reviewe

Maternal and fetal outcome in primigravida with unengaged head at term in labour

Background: Unengaged head in a primigravida at term gestation at the onset of labor is considered as an obstetric risk factor for dysfunctional labor. Careful monitoring of the progress of labor and timely medical intervention reduced the risk of dysfunctional labor and Cesarean delivery. This study was to assess the effect of unengaged head on course of labor, duration of labor, its maternal and fetal outcome in primigravida at term in labor. Methods: This prospective cross-sectional study was conducted in 100 primigravida with term gestation, unengaged head with spontaneous onset of labor meeting the inclusion criteria admitted to labor ward, Department of Obstetrics &amp; Gynecology, ESIC-MC &amp; PGIMSR Hospital, Bengaluru during January 2019 to June 2020. After detailed clinical evaluation, labor monitored partographically and CTG for fetal surveillance and when necessary, interventions like augmentation of labor and operative vaginal or cesarean delivery performed. Results: Among 100 primigravidae, 19% had floating head, 53% at -3 and 28% at -2 station at the time of onset of labor. The mean duration of 1st, 2nd stage and total duration of labor       was higher in freely floating head compared to -3 and -2 station. The need for augmentation of labor was 100% with freely floating head than with -3 and -2 station. 77% delivered vaginally and 23% by LSCS, arrest disorders being the main indication. There was no significant difference in maternal morbidity or APGAR score at 5 min. 88% of the babies delivered with good APGAR and 12% required NICU admission Conclusions: Our study demonstrates that higher the fetal head station at the onset of labor, greater the duration of labor and the need for augmentation. Unengaged head per se is not an indication for LSCS as 77% of them delivered vaginally with partographically monitored labor

Reclamation of Dye Affected Soil at Tirupur Region by Using Vermitechnology, South India

Soil from the dye affected area is taken for various analysis. Similarly soil from the fertile land is also taken for analysis in the same region. Most of the soils polluted by heavy metals can be reclaimed using a number of expensive tactics that either remove the contaminants or stabilize them within the soil .To analyze the parameters such as soil pH, temperature, soil fungal, bacterial and actinomycetes population of both the samples. Find out what are the metals present in the soil samples. Apply vermicompost to the dye affected soil for reclamation. Again we should analyze soil pH, temperature, fungal, bacterial and actinomycetes population of both the soil samples .The results are discussed with the literature.----------------------------------------------------------------------------------V. Prabhu, M. Ishwarya, S.R. Kayalvizhi, R. Hariprakash, and V. Balakrishnan*Department of Biotechnology, K.S.Rangasamy College of Technology, Tiruchengode-637 215, Tamilnadu, India*Corresponding Author, Email: [email protected] Please Cite This Article As:  V. Prabhu, M. Ishwarya, S.R. Kayalvizhi, R. Hariprakash, and V. Balakrishnan. 2010. Reclamation of Dye Affected Soil at Tirupur Region by Using Vermitechnology, South India. J. Ecobiotechnol. 2(4):16-21. Â