Non-ossifying fibroma of distal tibia: case report

Non-ossifying fibroma is a benign fibrohistiocytic lesion most commonly seen in the metaphyseal region in children. It usually doesn’t present with any symptoms. As the bone grows and undergoes remodeling, the lesion tends to vanish and get substituted with healthy bone. Nonetheless, the lesion can debilitate the affected bone, leading to a potential fracture. Here, we report a case of non-ossifying fibroma in the metaphyseal region of the tibia in a 13-year female. The patient presented with complaints of pain in the left leg for 5 months and underwent radiological investigation showing a well-defined, multi-loculated, expansile, radiolucent, lytic lesion with a thin sclerotic margin in the meta-diaphyseal region of the distal tibia, for which extended bone curettage with bone grafting was performed. The sample was sent for histopathological examination, which showed bony trabeculae with bits of tumor composed of spindle cells with elongated nuclei and scant cytoplasm, arranged in a storiform pattern along with many scattered multinucleate giant cells and foamy histiocytes suggestive of non-ossifying fibroma. Post operatively, non-weight bearing mobilization was advised for 4 weeks. Most non-ossifying fibromas were diagnosed in childhood to late adolescence, found incidentally, and clinically asymptomatic. Most distal tibial non-ossifying fibromas (NOFs) tend to transpire at a specific anatomical site located at the far end of the interosseous membrane. The prognosis for NOFs is typically excellent with a low risk of recurrence

Kinetics of Surface Enrichment: A Molecular Dynamics Study

We use molecular dynamics (MD) to study the kinetics of surface enrichment (SE) in a stable homogeneous mixture (AB), placed in contact with a surface which preferentially attracts A. The SE profiles show a characteristic double-exponential behavior with two length scales: \xi_-, which rapidly saturates to its equilibrium value, and \xi_+, which diverges as a power-law with time (\xi_+ \sim t^\theta). We find that hydrodynamic effects result in a crossover of the growth exponent from \theta \simeq 0.5 to \theta \simeq 1.0. There is also a corresponding crossover in the growth dynamics of the SE-layer thickness.Comment: 20 pages, 6 figures, Published in J. Chem. Phys. (Research Highlights

A Tensor-Based Formulation of Hetero-functional Graph Theory

Recently, hetero-functional graph theory (HFGT) has developed as a means to mathematically model the structure of large flexible engineering systems. In that regard, it intellectually resembles a fusion of network science and model-based systems engineering. With respect to the former, it relies on multiple graphs as data structures so as to support matrix-based quantitative analysis. In the meantime, HFGT explicitly embodies the heterogeneity of conceptual and ontological constructs found in model-based systems engineering including system form, system function, and system concept. At their foundation, these disparate conceptual constructs suggest multi-dimensional rather than two-dimensional relationships. This paper provides the first tensor-based treatment of some of the most important parts of hetero-functional graph theory. In particular, it addresses the "system concept", the hetero-functional adjacency matrix, and the hetero-functional incidence tensor. The tensor-based formulation described in this work makes a stronger tie between HFGT and its ontological foundations in MBSE. Finally, the tensor-based formulation facilitates an understanding of the relationships between HFGT and multi-layer networks

Optimizing Rooting Media for Enhanced Propagation of Guava (Psidium Guajava L.) Through Stem Cuttings

  Guava (Psidium guajava L.) is a significant tropical fruit crop that is primarily propagated through stem cuttings. The success of propagation through stem cuttings largely depends on the rooting medium used. Therefore, optimising the rooting medium is crucial for enhancing the success rate of guava propagation. This study was conducted in the Himalayan foot hill condition in the years 2021 and 2022 at Indian Institute of Soil and water conservation, Selaqui Dehradun, aimed to identify the optimal rooting medium for guava propagation through stem cuttings. The experiment tested three rooting media: sand (S), sawdust (SD), and a combination of the two, sand and sawdust (SSD), using semi-hardwood stem cuttings from guava trees. The study found that the SSD medium had the highest rooting success rate (94.5%), followed by Sand (87.5%) and Saw Dust (70%). The experiment suggests that semi-hardwood stem cuttings of guava roots are best in sawdust and sand, and this finding could contribute to enhancing the propagation of guava through stem cuttings

Pain outcomes in children who received intrathecal vs intravenous opioids for pain control following major urologic surgery: a retrospective review

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/115913/1/pan12781_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/115913/2/pan12781.pd

Gardner's syndrome in a 40-year-old woman: successful treatment of locally aggressive desmoid tumors with cytotoxic chemotherapy

BACKGROUND: Desmoid tumors that present as a part of Gardener's syndrome can present very difficult management problems. CASE PRESETATION: We report a case of intra-abdominal desmoid tumor causing distal small bowel obstruction that complicated the management of a more proximal enterocutaneous fistula from the jejunum. After failure of more conventional management options including imatinib, the patient's disease responded to doxorubicin and ifosfamide. The response resolved the bowel obstruction and allowed small intestinal resection to resolve the enterocutaneous fistula. CONCLUSION: Systemic cytotoxic therapy with doxorubicin and ifosfamide can be useful for patients with complications from intra-abdominal desmoid tumor