Laryngomalacia surgery: a series from a tertiary pediatric hospital

AbstractLaryngomalacia is the condition responsible for 75% of the cases of stridor in children aged up to 30 months, in which there is supraglottic collapse during inhalation. Inspiratory stridor is a characteristic telltale. As many as 20% of the patients are severely affected and require surgery. Supraglottoplasty is the procedure of choice and the presence of comorbidities is the most relevant prognostic factor for surgery success.ObjectiveTo describe a series in a tertiary pediatric hospital, its success rates, and surgery prognostic factors.MethodThis retrospective cohort study enrolled 20 patients submitted to supraglottoplasty between July 2007 and May 2011.ResultsThirteen (65%) patients were males; mean age at the time of the procedure was 6.32 months. Endoscopic examination showed that 12 subjects had combined forms of laryngomalacia, 40% had associated pharyngomalacia, and three also had tracheomalacia. Thirteen subjects had isolated laryngomalacia and seven had gastroesophageal reflux disease. Fifteen (75%) patients underwent aryepiglottic fold resection. After the procedure, eleven patients were asymptomatic and two required tracheostomy. Presence of comorbidities was the strongest predictor of unfavorable postoperative outcome (p = 0.034).ConclusionSupraglottoplasty is a safe therapeutical procedure for select patients with laryngomalacia

Análise bibliométrica da produção científica da Revista de Adminstração da UFSM: em busca de novas perspectivas e desafios

DOI: 10.5902/198346598551The Revista de Administração da Universidade Federal de Santa Maria (ReA/UFSM), founded in 2008, is an online publication of the Departamento de Ciências Administrativas of Centro de Ciências Sociais e Humanas from UFSM. The ReA/UFSM is gaining its place in academiaas an important vehicle for dissemination of publications in the business area. In this sense, this study aimed at analyzing the scientific publications of ReA/UFSM, in the period from 2008 to 2011. Thus, we analyzed all papers published in the periodic, in the last four years, representing 113 studies. Among the main results, it was found that the papers analyzed are mostly empirical, exploratory in nature, with qualitative approach predominantly. The analyzed data allow present an overview of the publications of ReA/UFSM, in the period from 2008 to 2011, enabling to defined new perspectives and challenges for the periodic.DOI: 10.5902/198346598551A Revista de Administração da Universidade Federal de Santa Maria (ReA/UFSM), criada em 2008, é uma publicação on-line do Departamento de Ciências Administrativas do Centro de Ciências Sociais e Humanas da UFSM. A ReA/UFSM vem conquistando o seu espaço no meio acadêmico como um importante veículo para difusão das publicações na área de Administração. Nesse contexto, este estudo teve como objetivo analisar as publicações científicas da ReA/UFSM no período de 2008 a 2011. Para tanto, foram analisados todos os artigos publicados na revista nos últimos quatro anos, o que totaliza 113 artigos. Dentre os principais resultados, constatou-se que os artigos são, em sua maioria, empíricos e de natureza exploratória, com a predominância da abordagem e dos métodos qualitativos. Os dados coletados e analisados permitem traçar um panorama das publicações da ReA/UFSM no período de 2008 a 2011 e, consequentemente, definir novas perspectivas e desafios para a revista.

Variación en la reparación de un injerto costal utilizado para reconstrucción mandibular después de 20 años

Mandibular reconstruction has been used in the last 100 years as a safe, effective and stable technique. Various types of grafts have been used, including the autogenous rib graft; the normal repair of this type of graft has been defined in some studies although some observations have been made indicating low predictability of the growth of this bone. The aim of this study was to report the case of a patient with a rib graft for mandibular reconstruction where after 20 years cartilaginous tissue was observed exclusively in the absence of bone tissue. A 61-year-old female patient presented in the Oral and Maxillofacial Surgery Service for dental implants. The patient had a history of 4 previous mandibular reconstructions; imaging showed no alterations to the normal evolution of a graft. However, the intraoral access contained softer tissue than the normal bone, and thus the implant installation was abandoned. Histopathological analysis revealed the formation of collagenous tissue and cartilage, chondrocytes island conditions characteristic of cartilaginous tissue in the absence of mineralization and cancellous bone. This led to the conclusion that repair conditions can vary based on specific and general factors as yet under discussion.Mandibular reconstruction has been used in the last 100 years as a safe, effective and stable technique. Various types of grafts have been used, including the autogenous rib graft; the normal repair of this type of graft has been defined in some studies a332719724sem informaçãosem informaçãoLa reconstrucción mandibular ha sido utilizada en los últimos 100 años como una técnica segura, eficaz y estable. Diversos tipos de injertos se han utilizado siendo el auto trasplante de hueso costal uno de ellos; la normal reparación de este tipo de inj

COVID-19 in otolaryngologists: a cross-sectional multicenter study

Introduction: The nose and throat are areas of high viral load, which could place otolaryngologists at an even higher risk for COVID-19 than other health-care workers. Objective: To investigate the prevalence of antibodies against SARS-CoV-2 in otorhinolaryngologists in southern Brazil, its relationship to demographic data, professional practice and reported symptoms of COVID-19, and compare it with official data on other health-care workers of the state and the general population in the same period. Methods: In this cross-sectional multicenter study, otolaryngologists actively practicing officially registered in Rio Grande do Sul were screened for IgM and IgG antibodies against SARS-CoV-2 from August 1 to September 15, 2020. A questionnaire was also applied. Results: We screened 358 (80.1%) of 447 actively practicing otolaryngologists (195 [54.5%] male; mean [SD] age, 47.77 [13.57] years; range, 26–84 years). Twenty-three were positive for IgM and/or IgG (6.4%). This result was significantly associated with reports of infected household contacts (19/315 negatives and 8/23 positives; p < 0.001). From 23 seropositive participants, 14 were asymptomatic (60.9%; p < 0.001). There were no significant associations between seroconversion and age, sex, number of patient appointments and surgical procedures, workplace (hospital or private practice), patients with or without respiratory symptoms, or level of personal protective equipment used. The rate of COVID-19 in all health-care workers in the state was 7.69% at the end of the same period. Data from state government seroprevalence was 5.26 (risk ratio [RR]; 95% CI 3.27–8.45) and 4.66 (RR; 95% CI 2.93–7.43) times higher in otolaryngologists than in the general population in August and September, respectively. Conclusion: Otolaryngologists had a higher seroconversion rate than the general population. Using personal protective equipment, the level of occupational exposure did not result in higher rates of infection than other health-care workers, but the presence of infected household contacts was associated with higher rates of seroconversion

Complete genome sequence of the sugarcane nitrogen-fixing endophyte gluconacetobacter diazotrophicus PAL5

17 p. : il.Background: Gluconacetobacter diazotrophicus Pal5 is an endophytic diazotrophic bacterium that lives in association with sugarcane plants. It has important biotechnological features such as nitrogen fixation, plant growth promotion, sugar metabolism pathways, secretion of organic acids, synthesis of auxin and the occurrence of bacteriocins. Results: Gluconacetobacter diazotrophicus Pal5 is the third diazotrophic endophytic bacterium to be completely sequenced. Its genome is composed of a 3.9 Mb chromosome and 2 plasmids of 16.6 and 38.8 kb, respectively. We annotated 3,938 coding sequences which reveal several characteristics related to the endophytic lifestyle such as nitrogen fixation, plant growth promotion, sugar metabolism, transport systems, synthesis of auxin and the occurrence of bacteriocins. Genomic analysis identified a core component of 894 genes shared with phylogenetically related bacteria. Gene clusters for gum-like polysaccharide biosynthesis, tad pilus, quorum sensing, for modulation of plant growth by indole acetic acid and mechanisms involved in tolerance to acidic conditions were identified and may be related to the sugarcane endophytic and plant-growth promoting traits of G. diazotrophicus. An accessory component of at least 851 genes distributed in genome islands was identified, and was most likely acquired by horizontal gene transfer. This portion of the genome has likely contributed to adaptation to the plant habitat. Conclusion: The genome data offer an important resource of information that can be used to manipulate plant/bacterium interactions with the aim of improving sugarcane crop production and other biotechnological applications