Peculiarities of the State of the Body's Immunoprotective Functions, Bacterioscopic and Cytological Studies in the Presence of a Chronic Inflammatory Process of the Reproductive System

At the current stage, the state of health of the Ukrainian nation of reproductive age is characterized by a low birth rate. Chronic inflammatory diseases of the reproductive system significantly affect the health of millions of people of childbearing age. Chronic inflammation is characterized by a protracted, often erased course, a tendency to relapse, the presence of complications and resistance to therapy. The development and formation of inflammatory diseases are based on interconnected processes that begin with acute inflammation and end with destructive changes, therefore the assessment of the body's adaptive capabilities is increasingly considered one of the most important health criteria. There is a whole series of integral hematological indicators that allow you to assess the state of various parts of the immune system without resorting to special research methods

Features of Indicators of Blood General Clinical Analysis and the Summary Analysis of an Organism’s General Reactivity at Chronic Inflammatory Process

Inflammatory diseases cause health disorders which result in a reduction of the population. That is why this medical problem is considered to be a very important one. The human immune system is responsible for protecting the body from infections of various origins, while inducing chronic inflammation (characterized by a long, often invisible course) which can result in proneness to recurrence, complications and resistance to therapy. The authors of the article analyzed and proved that there are immune status shifts in patients with chronic nonspecific inflammatory processes depending on the pathogen, phase and level of damage

Assessment of the Nature of Dyslipoproteinemias and Correlations of Indicators of General Reactivity and Lipid Metabolism in Patients with Chronic Nonspecific Inflammation of the Reproductive System

Metabolic disorders can occur at all levels of biological organization - from molecular and cellular to the level of the organism as a whole. These changes may result from disruptions in hormonal mechanisms, actions of pathogenic factors, or infections. Primary metabolic disorders are the basis of many diseases, such as diabetes, obesity, and atherosclerosis, while secondary disorders accompany most pathological processes. Disruption of lipid metabolism leads to changes in their functions and the development of pathological processes, such as dyslipoproteinemia, and also contributes to the development of atherosclerosis. Various intracellular infectious agents play a significant role in the development of dyslipoproteinemias and atherosclerosis, for example, chlamydia can alter the lipid metabolism in macrophages under the influence of low-density lipoproteins, leading to the formation of 'foam-like' cells. This, in turn, contributes to the development of atheromatous plaques-a favorable environment for chlamydia, where it can survive for an extended period and trigger immunopathological mechanisms

Assessment of the State of Platelet Haemostasis and Adhesive - Aggregation Properties of Platelets as a Factor of Increasing the Tendency to Thrombosis in Chronic Inflammation

In recent decades, considerable progress has been made in understanding the functional mechanisms of platelets and the correction of platelet haemostasis. Platelets are considered the most important participants in both the normal and pathological thrombotic processes characteristic of a variety of diseases and conditions. Alterations in various limbs of haemostasis are found in many somatic diseases (atherosclerosis, coronary heart disease, stroke), surgical procedures, oncological and immunological diseases. Inflammation underlies most diseases and remains an urgent problem in medicine. In the leukocyte infiltration of the inflammatory focus, the mechanism of its self-preservation is of great importance. The activation of haematopoiesis during inflammation is triggered by factors released by stimulated leukocytes of the focus and peripheral blood. Therefore, the problem of the state of the haemostasis system should be the focus of constant attention of clinicians, and with the help of laboratory monitoring of the state of the haemostasis system, it is possible to carry out drug correction of the haemocoagulation potential

Definition features of the efficiency in railways management

The article deals with the determination of general effectiveness of managerial influences on the activity of the railway industry, taking into account such partial indicators as public, functional and economic efficiency. appropriate degree of satisfaction of requirements and expectations of consumers on the quality of transport services, as well as the degree of satisfaction of staff with the work conditions are used to assess the public effectiveness of management in railway transport. Functional efficiency of management in railway transport can be estimated by the conformity of managerial decisions to the functional goals and tasks of management, achievement of optimal results within the requirements of state regulation of the industry, etc. The economic efficiency of railway transport management has traditionally been evaluated by the degree of maximization of profitability of freight transport and minimization of losses from passenger transportation with rational use of industry resources

Effectiveness of Psycho-Correctional Methods and Technologies in Work with Children who have Autism: Systematic Review

Background: Proper care for children with autism spectrum disorder can help reduce the difficulties faced by autistic people throughout their life. This fact causes the necessity to study the most effective therapy, teaching and development methods, social interaction skills, and emotional intelligence for children with autism. Objective: This article is aimed at identifying the most effective methods and technologies in working with children who have autism that was described in the scientific works and at revealing reasons and necessities for their more detailed study as well as possibilities to implement them. Methods: Using methods analysis, comparison and analogy, statistical method, and generalization, several publications dedicated to correction methods in work with children who have autism were selected. The most common correction methods were indicated and described according to efficacy and frequency. Results: A thorough review of research, publications, and available information on the Internet were conducted. The most effective methods and technologies in working with autistic children were identified, which included applied behavioral therapy, treatment and education of autistic and related communication-handicapped children, Floortime, parent-child interaction therapy, method Tomatis, and the program Son-rise. Recent intelligent technologies were also considered, particularly Smart Platforms for Research, intervention, and Neurodevelopmental growth, the use of virtual reality, and the program Empowered Brain technology. Conclusions: The authors emphasize the necessity of thorough psychodiagnostics and the formation of psycho-correctional tasks based on exclusively personal needs, symptoms of the disorder, and disease etiology. The analysis of modern psycho-correctional technologies leads to the conclusion that their effectiveness depends, first of all, on the correct expedient application in each particular case

Psychological and Pedagogical Aspects of Consolidation of Social Capital of Higher Education Institutions

The aim of the study was to identify psychological and pedagogical factors that ensure the consolidation of social capital in higher education institutions and to assess their effectiveness through expert critical evaluations. The study used the exploratory design and was based on the use of qualitative methods to evaluate the selected studies. The research methodology relied on the methods recommended for feasibility studies to determine the possibility of implementation of the selected best practices. The systematic review of scientific sources and best practices found the psychological and pedagogical aspects that ensure the consolidation of social capital in higher education institutions, namely: individual psychological factors of economically motivated behaviour, social network technology, second-order psychological factors, teachers' assistance of students' professional self-determination, education as a means, and psychological factors based on the attributes of the institution. The results of expert evaluation of the above factors suggest that the last three ones mentioned have the potential for duplication, dissemination and transferability in higher education institutions in Ukraine