Plasma lipid profiles discriminate bacterial from viral infection in febrile children

Fever is the most common reason that children present to Emergency Departments. Clinical signs and symptoms suggestive of bacterial infection ar

The ongoing quest for the IT artifact: looking back, moving forward

More than 10 years ago, Orlikowski and Iacono (2001) examined the conceptualization of Information Technology (IT) in Information Systems Research (ISR) articles published in the 1990s. Their main conclusion was that the majority of these articles did not properly conceptualize the IT artifact. They recommended that IS researchers start to theorize about the IT artifact and employ rich conceptualizations of IT. The Orlikowski and Iacono paper provides a strong anchor point from which to analyze the evolution of the IS discipline. In order to obtain an up-to-date image of contemporary IS research, and to assess how the IS field has evolved since the 1990s, we carried out a similar analysis on a more recent and broader set of articles, that is, the full set (N=644) of papers published between 2006 and 2009 by six top North American (ISR, MISQ, JAIS) and European (JIT, ISJ, EJIS) journals. The statistics in our results reveal no drastic advance in terms of deeper engagement with the IT artifact; more than 39% of the articles in our set are virtually mute about the artifact, and less than 16% employ an ensemble view of IT. Moreover, we note differences among the North American and European journals. Implications of the findings for two perspectives central to the IS research legitimacy debate are discussed

Measuring marine fish biodiversity: temporal changes in abundance, life history and demography

Patterns in marine fish biodiversity can be assessed by quantifying temporal variation in rate of population change, abundance, life history and demography concomitant with long-term reductions in abundance. Based on data for 177 populations (62 species) from four north-temperate oceanic regions (Northeast Atlantic and Pacific, Northwest Atlantic, North mid-Atlantic), 81% of the populations in decline prior to 1992 experienced reductions in their rate of loss thereafter; species whose rate of population decline accelerated after 1992 were predominantly top predators such as Atlantic cod (Gadus morhua), sole (Solea solea) and pelagic sharks. Combining population data across regions and species, marine fish have declined 35% since 1978 and are currently less than 70% of recorded maxima; demersal species are generally at historic lows, pelagic species are generally stable or increasing in abundance. Declines by demersal species have been associated with substantive increases in pelagic species, a pattern consistent with the hypothesis that increases in the latter may be attributable to reduced predation mortality. There is a need to determine the consequences to population growth effected by the reductions in age (21%) and size (13%) at maturity and in mean age (5%) and size (18%) of spawners, concomitant with population decline. We conclude that reductions in the rate of population decline, in the absence of targets for population increase, will be insufficient to effect a recovery of marine fish biodiversity, and that great care must be exercised when interpreting multi-species patterns in abundance. Of fundamental importance is the need to explain the geographical, species-specific and habitat biases that pervade patterns of marine fish recovery and biodiversity

Improving the Applicability of Environmental Scanning Systems: State of the Art and Future Research

Part 5: Future SubjectsInternational audienceThe 2008/2009 economic crisis provided a sustainable impulse for improving environmental scanning systems (ESS). Although a rich body of know-ledge exists, concepts are not often used in practice. This article contributes a literature review addressing six findings for ESS design to become more applicable than the state of the art. They are structured by the elements of information systems (IS) design theories. Addressing the lack of a sound requirements analysis, our first finding proposes 360-degree ESS for executives’ "managing a company" task and presents how to select just the most important scanning areas to keep focus. Three other findings cover the IS model perspective focusing on a better "grasp" of weak signals: define concrete indicators and use IT to identify relevant cause-effective-chains, leverage IT to automate day-to-day routines and monitor the variety of indicators’ movements, and—as a fourth finding—leverage expert experience with an impact matrix and translate indicators’ impact into a balanced opportunity-and-threat portfolio. From the methods perspective on ESS, we propose to more closely incorporate scanning results into executives’ decision-making process by generating scenarios from a set of environment assumptions as well as to use retrospective controls to continuously update the ESS and collaborate to share the scanning findings day-to-day