Towards an Understanding of the Creative Generation: New Frameworks for Arts Education for Students with Disabilities

https://remix.berklee.edu/able-assembly-conference/1044/thumbnail.jp

Sympatric and Allopatric Divergence of MHC Genes in Threespine Stickleback

Parasites can strongly affect the evolution of their hosts, but their effects on host diversification are less clear. In theory, contrasting parasite communities in different foraging habitats could generate divergent selection on hosts and promote ecological speciation. Immune systems are costly to maintain, adaptable, and an important component of individual fitness. As a result, immune system genes, such as those of the Major Histocompatability Complex (MHC), can change rapidly in response to parasite-mediated selection. In threespine stickleback (Gasterosteus aculeatus), as well as in other vertebrates, MHC genes have been linked with female mating preference, suggesting that divergent selection acting on MHC genes might influence speciation. Here, we examined genetic variation at MHC Class II loci of sticklebacks from two lakes with a limnetic and benthic species pair, and two lakes with a single species. In both lakes with species pairs, limnetics and benthics differed in their composition of MHC alleles, and limnetics had fewer MHC alleles per individual than benthics. Similar to the limnetics, the allopatric population with a pelagic phenotype had few MHC alleles per individual, suggesting a correlation between MHC genotype and foraging habitat. Using a simulation model we show that the diversity and composition of MHC alleles in a sympatric species pair depends on the amount of assortative mating and on the strength of parasite-mediated selection in adjacent foraging habitats. Our results indicate parallel divergence in the number of MHC alleles between sympatric stickleback species, possibly resulting from the contrasting parasite communities in littoral and pelagic habitats of lakes

Gravitational probes of ultra-light axions

The axion is a hypothetical, well-motivated dark-matter particle whose existence would explain the lack of charge-parity violation in the strong interaction. In addition to this original motivation, an `axiverse' of ultra-light axions (ULAs) with masses $10^{-33}\,{\rm eV}\lesssim m_{\rm a}\lesssim 10^{-10}\,{\rm eV}$ also emerges from string theory. Depending on the mass, such a ULA contributes to the dark-matter density, or alternatively, behaves like dark energy. At these masses, ULAs' classical wave-like properties are astronomically manifested, potentially mitigating observational tensions within the $\Lambda$CDM paradigm on local-group scales. ULAs also provide signatures on small scales such as suppression of structure, interference patterns and solitons to distinguish them from heavier dark matter candidates. Through their gravitational imprint, ULAs in the presently allowed parameter space furnish a host of observational tests to target in the next decade, altering standard predictions for microwave background anisotropies, galaxy clustering, Lyman-$\alpha$ absorption by neutral hydrogen along quasar sightlines, pulsar timing, and the black-hole mass spectrum