Occupational Therapy’s Role in Early Language Development of Babies and Young Children

Occupational therapy practitioners in their interactions with babies, young children and their families, can be change-agents who promote rich language environments as a foundation to social interactions, social participation and academic successes. OTPs may be the sole provider working with a family or may reinforce with families the plan of care developed by speech-language pathologists (SLP) or early intervention teachers. The first step for OTPs is deeper knowledge of the importance of early language exposure, social interaction and participation development in young children and approaches that promotes rich language environments

Generalized Hot Enhancons

We review what has been learnt and what remains unknown about the physics of hot enhancons following studies in supergravity. We recall a rather general family of static, spherically symmetric, non-extremal enhancon solutions describing D4 branes wrapped on K3 and discuss physical aspects of the solutions. We embed these solutions in the six dimensional supergravity describing Type IIA strings on K3 and generalize them to have arbitrary charge vector. This allows us to demonstrate the equivalence with a known family of hot fractional D0 brane solutions, to widen the class of solutions of this second type and to carry much of the discussion across from the D4 brane analysis. In particular we argue for the existence of a horizon branch for these branes.Comment: 25 pages, Late

Postsecondary Education Students with Disabilities’ Perceptions of Occupational Therapy-Led Coaching

Background: Students with disabilities attending postsecondary education (PSE) institutions have poor degree progression, retention, and graduation rates. PSE institutions are addressing these challenges in various ways, including the delivery of occupational therapy (OT)-led coaching. There is emerging evidence that coaching increases academic success and self-determination in PSE. The students’ perspectives about the benefits of OT-led coaching intervention has yet to be explored. Method: A phenomenological study was conducted using transcribed semi-structured interviews with 18 college students with disabilities. Qualitative data analysis was conducted through an immersive inter-coder process that included independent coding, comparison of codes, discrepancy resolution to combine or redefine codes, and theme identification. Results: Overall, the participants reported perceiving the OT-led coaching intervention as beneficial to them. Specifically, four major themes emerged from the data: the personal and academic growth achieved, the benefits of an open and supportive environment in the coaching program, the participants’ perception of self-identified goal achievement, and the importance of accountability and engagement. Conclusion: The students with disabilities perceived that the OT-led coaching intervention was beneficial and identified aspects of the intervention that were most useful to them, including the emotional and material support

A Systematic Review: Light Therapy for Individuals with Dementia and Implications for Practice

This systematic review seeks to answer the question: is light therapy an effective intervention for sundowning symptoms experienced by individuals who have dementia

A Systematic Review of the Efficacy of Motivational Interviewing on Occupational Performance

This systematic review aims to review the efficacy of MI to address such performance goals falling within the occupational therapy scope of practice

How we work: A critical approach to program development to serve library/dh partnerships

Science and Digital Humanities exert influences on one another, particularly as practices and tools developed in the sciences are imagined, borrowed, and manipulated by DH, but also as practices and insights from the humanities are applied to scientific inquiry. With this poster, we present an analysis of studies of how digital humanists and scientists work, testing the oft-referenced distinctions and similarities claimed between science and DH models and interrogating the ways that scientific disciplinarity affects digital humanities processes and products. Our research critically evaluates the comparisons drawn between epistemological and labor models in DH and the sciences

Amantadine and levodopa in the treatment of Parkinson's disease

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/117040/1/cpt197213128.pd

Efficacy of Work-Related Training for Individuals with Autism Spectrum Disorder

Research suggests that traditional models of work-related training, in addition to a lack of on-the-job support, may exacerbate difficulties experienced by individuals with autism spectrum disorder with obtaining and maintaining employment The poor employment outcomes experienced by individuals with ASD are well-documented throughout literature and have resulted in the need to examine more effective ways of providing support and work-related interventions. Although research has investigated the efficacy of work-related training on successful employment outcomes when used with individuals with ASD, a systematic review summarizing this evidence has yet to be published. Therefore, this review examines and interprets current research evidence on the efficacy of work-related training for individuals

Spatial Intensity Distribution Analysis Reveals Abnormal Oligomerization of Proteins in Single Cells

AbstractKnowledge of membrane receptor organization is essential for understanding the initial steps in cell signaling and trafficking mechanisms, but quantitative analysis of receptor interactions at the single-cell level and in different cellular compartments has remained highly challenging. To achieve this, we apply a quantitative image analysis technique—spatial intensity distribution analysis (SpIDA)—that can measure fluorescent particle concentrations and oligomerization states within different subcellular compartments in live cells. An important technical challenge faced by fluorescence microscopy-based measurement of oligomerization is the fidelity of receptor labeling. In practice, imperfect labeling biases the distribution of oligomeric states measured within an aggregated system. We extend SpIDA to enable analysis of high-order oligomers from fluorescence microscopy images, by including a probability weighted correction algorithm for nonemitting labels. We demonstrated that this fraction of nonemitting probes could be estimated in single cells using SpIDA measurements on model systems with known oligomerization state. Previously, this artifact was measured using single-step photobleaching. This approach was validated using computer-simulated data and the imperfect labeling was quantified in cells with ion channels of known oligomer subunit count. It was then applied to quantify the oligomerization states in different cell compartments of the proteolipid protein (PLP) expressed in COS-7 cells. Expression of a mutant PLP linked to impaired trafficking resulted in the detection of PLP tetramers that persist in the endoplasmic reticulum, while no difference was measured at the membrane between the distributions of wild-type and mutated PLPs. Our results demonstrate that SpIDA allows measurement of protein oligomerization in different compartments of intact cells, even when fractional mislabeling occurs as well as photobleaching during the imaging process, and reveals insights into the mechanism underlying impaired trafficking of PLP

Hydrodynamic properties of fin whale flippers predict maximum rolling performance

Maneuverability is one of the most important and least understood aspects of animal locomotion. The hydrofoil-like flippers of cetaceans are thought to function as control surfaces that effect maneuvers, but quantitative tests of this hypothesis have been lacking. Here, we constructed a simple hydrodynamic model to predict the longitudinal-axis roll performance of fin whales, and we tested its predictions against kinematic data recorded by on-board movement sensors from 27 free-swimming fin whales. We found that for a given swimming speed and roll excursion, the roll velocity of fin whales calculated from our field data agrees well with that predicted by our hydrodynamic model. Although fluke and body torsion may further influence performance, our results indicate that lift generated by the flippers is sufficient to drive most of the longitudinal-axis rolls used by fin whales for feeding and maneuvering