Festchrift: A Collection of Essays on Architectural History

A collection of essays on architectural history prepared by the Northern Pacific Coast Chapter Society of Architectural Historians dedicated to Professor Marion Dean Ross, chapter founder, on the occasion of his 65th birthday

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

2010 Conference Report

Summary of annual chapter conference events and proceedings as recorded by chapter secretary or designate

Marion Dean Ross Chapter of the Society of Architectural Historians Records, 1969-

This is a finding aid, prepared by Elisabeth Walton Potter, to the Marion Dean Ross chapter archives held in Special Collections & University Archives, University of Oregon Libraries, Collection 316

A History of HABS and HAER in Oregon 1933-1983; a program in observance of the 50th anniversary of the founding of the Historic American Building Survey.

Typescript of a two-part presentation commemorating a half-century of documenting Oregon's architectural heritage through the Historic American Building Survey. Consists of "Part I, The American Institute of Architects and the Historic American Buildings Survey in Oregon 1930-1940," by Elisabeth Walton Potter, Oregon State Historic Preservation Office, Salem, Oregon, and "Part II, Historic American Buildings Survey and the Historic American Engineer Record to the Present Day," by Alfred M. Staehli, A. I. A., Portland, Oregon. Digitized from a copy provided with permission to publish by author Elisabeth Walton Potter, member of the Marion Dean Ross / Pacific Northwest Chapter of the Society of Architectural Historians.National Park Service, the Historic Preservation League of Oregon, the Oregon Committee for the Humanities, the American Institute of Architect

“Sacred to the Hart”*: Identity and dignity as reflected in the memorial landscapes of postemancipation African Americans in Pensacola, Florida

This article broadens the discussion of 19th century monuments associated with the Lost Cause by exploring the monument landscapes of post-emancipation African American cemeteries and the people who are associated with them. Method. Exemplars from several cemeteries in Pensacola, Florida, are used to examine how the post-emancipation population maintained deep ties to their cultural roots while assimilating into society as free people. Results. The built environment of postemancipation African American cemeteries contains monuments reflecting black identity and dignity in life and in death. Conclusions. Examining a broader sample of memorial landscapes can be a starting point in expanding the national dialogue on our country’s history in a more inclusive fashion. Historic cemeteries, especially African American cemeteries established post-Civil War, offer an excellent means of doing this in a manner that almost all citizens can understand and respectJournal ArticlePublishe