7,383 research outputs found
Semirelativistic stability of N-boson systems bound by 1/r pair potentials
We analyze a system of self-gravitating identical bosons by means of a
semirelativistic Hamiltonian comprising the relativistic kinetic energies of
the involved particles and added (instantaneous) Newtonian gravitational pair
potentials. With the help of an improved lower bound to the bottom of the
spectrum of this Hamiltonian, we are able to enlarge the known region for
relativistic stability for such boson systems against gravitational collapse
and to sharpen the predictions for their maximum stable mass.Comment: 11 pages, considerably enlarged introduction and motivation,
remainder of the paper unchange
Effects of carbon dioxide on trapped electrolyte hydrogen-oxygen, alkaline fuel cells
Effects of carbon dioxide on trapped electrolyte hydrogen-oxygen alkaline fuel cell
The Two Modes of Visual Processing: Implications for Spatial Orientation
The roles of the focal and ambient visual systems in spatial orientation are discussed. The two modes are defined and compared. The contribution of each system is illustrated through examples such as spatial disorientation/motion sickness, vehicle guidance/night driving, visual narrowing under stress/cortical brain damage, and aircraft instrumentation. Emphasis is placed on the need for testing procedures for the ambient system
The ral exchange factor rgl2 promotes cardiomyocyte survival and inhibits cardiac fibrosis
Cardiomyocytes compensate to acute cardiac stress by increasing in size and contractile function. However, prolonged stress leads to a decompensated response characterized by cardiomyocyte death, tissue fibrosis and loss of cardiac function. Identifying approaches to inhibit this transition to a decompensated response may reveal important targets for treating heart failure. The Ral guanine nucleotide disassociation (RalGDS) proteins are Ras-interacting proteins that are upregulated by hypertrophic stimuli. The Ral guanine nucleotide dissociation stimulator-like 2 (Rgl2) is a member of the RalGDS family that modulates expression of hypertrophic genes in cardiomyocytes. However, the pathophysiologic consequence of increased Rgl2 expression in cardiomyoctyes remains unclear. To evaluate the effect of increasing Rgl2 activity in the heart, transgenic mice with cardiac-targeted over-expression of Rgl2 were generated. Although Ral activation was increased, there were no apparent morphologic or histological differences between the hearts of Rgl2 transgenic and nontransgenic mice indicating that increased Rgl2 expression had no effect on basal cardiac phenotype. To determine if Rgl2 modulates the cardiac response to stress, mice were infused with the Ăź-adrenergic receptor agonist, isoproterenol. Isoproterenol infusion increased heart mass in both Rgl2 transgenic and nontransgenic mice. However, unlike nontransgenic mice, Rgl2 transgenic mice showed no morphologic evidence of cardiomyocyte damage or increased cardiac fibrosis following isoproterenol infusion. Increased Rgl2 expression in cultured cardiomyocytes stimulated Ral activation and inhibited staurosporine-induced apoptosis via increased activation of PI3-kinase. Activation of the PI3-kinase signaling pathway was confirmed in hearts isolated from Rgl2 transgenic mice. Increased expression and function of Rgl2 in cardiomyocytes promotes activation of the PI3-kinase signaling cascade and protects from carciomyocyte death and pathologic cardiac fibrosis. Taken further, these results suggest that Rgl2 upregulation in hypertrophic hearts may be a protetive mechanism, and that Rgl2 may be a novel therapeutic target in treating heart disease
Maxwell's theory on a post-Riemannian spacetime and the equivalence principle
The form of Maxwell's theory is well known in the framework of general
relativity, a fact that is related to the applicability of the principle of
equivalence to electromagnetic phenomena. We pose the question whether this
form changes if torsion and/or nonmetricity fields are allowed for in
spacetime. Starting from the conservation laws of electric charge and magnetic
flux, we recognize that the Maxwell equations themselves remain the same, but
the constitutive law must depend on the metric and, additionally, may depend on
quantities related to torsion and/or nonmetricity. We illustrate our results by
putting an electric charge on top of a spherically symmetric exact solution of
the metric-affine gauge theory of gravity (comprising torsion and
nonmetricity). All this is compared to the recent results of Vandyck.Comment: 9 pages, REVTeX, no figures; minor changes, version to be published
in Class. Quantum Gra
Crisis intervention and acute psychiatry in Amsterdam: 20 years of change? A historical comparison of consultations in 1983 and 2004-2005
Are Individuals Fickle-Minded?
Game theory has been used to model large-scale social events — such as constitutional law, democratic stability, standard setting, gender roles, social movements, communication, markets, the selection of officials by means of elections, coalition formation, resource allocation, distribution of goods, and war — as the aggregate result of individual choices in interdependent decision-making. Game theory in this way assumes methodological individualism. The widespread observation that game theory predictions do not in general match observation has led to many attempts to repair game theory by creating behavioral game theory, which adds corrective terms to the game theoretic predictions in the hope of making predictions that better match observations. But for game theory to be useful in making predictions, we must be able to generalize from an individual’s behavior in one situation to that individual’s behavior in very closely similar situations. In other words, behavioral game theory needs individuals to be reasonably consistent in action if the theory is to have predictive power. We argue on the basis of experimental evidence that the assumption of such consistency is unwarranted. More realistic models of individual agents must be developed that acknowledge the variance in behavior for a given individual
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