49 research outputs found
Profesionalizaci贸n empresarial en empresas familiares: una construcci贸n te贸rica
La empresa familiar es una de las organizaciones productivas con mayor presencia en el mundo, sin embargo, tiene una estructura particular, ya que en ella se conjugan dos sistemas con l贸gicas distintas: la familia y la empresa. La primera act煤a en pro del bienestar del grupo familiar, y la segunda, responde a criterios de racionalidad econ贸mica.
En la actualidad, estas organizaciones se enfrentan a importantes retos, uno derivado de la esfera externa, que guarda relaci贸n con el proceso de globalizaci贸n, el cual exige a las empresas un mayor nivel de competitividad; y otro propiciado por su din谩mica interna, como lo es lograr el balance entre los intereses y objetivos de la empresa y la familia. Por tanto, la profesionalizaci贸n empresarial surge como una alternativa para enfrentar o paliar dichas disyuntivas y alcanzar la longevidad de las mismas.
De all铆 que el presente libro exponga los hallazgos derivados de la investigaci贸n que lo gest贸, que tuvo como objetivo construir un sistema te贸rico que fundamente el proceso de profesionalizaci贸n empresarial en las empresas de car谩cter familiar.
El enfoque epistemol贸gico seguido es el emp铆rico鈥搃nductivo, el tipo de investigaci贸n siguiendo la estructura diacr贸nica del proceso de investigaci贸n transita por la fases descriptiva, y la explicativa鈥揷ontrastiva. La poblaci贸n objeto de estudio est谩 constituida por las cadenas de hipermercados y supermercados familiares en Venezuela, de cuyo comportamiento y visi贸n se deriv贸 como resultado fundamental un sistema te贸rico que orientar谩 la consecuci贸n de la profesionalizaci贸n en las empresas familiares.
Con esta finalidad tendr谩n que crear las estructuras de gobierno y gesti贸n empresarial, mediante la formalizaci贸n de sistemas, 贸rganos, pr谩cticas y pol铆ticas que regulen el desempe帽o en materia organizativa, recursos humanos, estructuras de gobierno corporativo y herramientas tecnol贸gicas de apoyo a la gerencia.The family business is one of the productive organizations with greater presence in the world, however, it has a particular structure, since it combines two systems with different logics: the family and the company. The first acts for the welfare of the family group, and the second, responds to criteria of economic rationality.
Currently, these organizations face important challenges, one derived from the external sphere, which is related to the process of globalization, which requires companies a greater level of competitiveness; and another one propitiated by its internal dynamics, as it is to achieve the balance between the interests and objectives of the company and the family. Therefore, business professionalization emerges as an alternative to face or mitigate these dilemmas and achieve the longevity of them.
Hence, the present book exposes the findings derived from the research that created it, which aimed to build a theoretical system that supports the process of business professionalization in family businesses.
The epistemological approach followed is the empirical-inductive, the type of research following the diachronic structure of the research process transits through the descriptive phases, and the explanatory-contrastive one. The population under study is constituted by chains of hypermarkets and family supermarkets in Venezuela, whose behavior and vision was derived as a fundamental result a theoretical system that will guide the achievement of professionalization in family businesses.
To this end they will have to create the structures of governance and business management, through the formalization of systems, bodies, practices and policies that regulate organizational performance, human resources, corporate governance structures and technological tools to support management
Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells
Paclitaxel is a treatment option for advanced or metastatic bladder cancer after the failure of first-line cisplatin and gemcitabine, although resistance limits its clinical benefits. Mcl-1 is an anti-apoptotic protein that promotes resistance to paclitaxel in different tumors. Obatoclax, a BH3 mimetic of the Bcl-2 family of proteins, antagonizes Mcl-1 and hence may reverse paclitaxel resistance in Mcl-1-overexpressing tumors. In this study, paclitaxel-sensitive 5637 and -resistant HT1197 bladder cancer cells were treated with paclitaxel, obatoclax, or combinations of both. Apoptosis, cell cycle, and autophagy were measured by Western blot, flow cytometry, and fluorescence microscopy. Moreover, Mcl-1 expression was analyzed by immunohistochemistry in bladder carcinoma tissues. Our results confirmed that paclitaxel alone induced Mcl-1 downregulation and apoptosis in 5637, but not in HT1197 cells; however, combinations of obatoclax and paclitaxel sensitized HT1197 cells to the treatment. In obatoclax-treated 5637 and obatoclax + paclitaxel-treated HT1197 cells, the blockade of the autophagic flux correlated with apoptosis and was associated with caspase-dependent cleavage of beclin-1. Obatoclax alone delayed the cell cycle in 5637, but not in HT1197 cells, whereas combinations of both retarded the cell cycle and reduced mitotic slippage. In conclusion, obatoclax sensitizes HT1197 cells to paclitaxel-induced apoptosis through the blockade of the autophagic flux and effects on the cell cycle. Furthermore, Mcl-1 is overexpressed in many invasive bladder carcinomas, and it is related to tumor progression, so Mcl-1 expression may be of predictive value in bladder cancer.Espa帽a, Sistema P煤blico Andaluz Biobanco y ISCIII-Red de Biobancos PT17/0015/004
Information and communications technologies and business professionalism in family hypermarkets and supermarkets in Venezuela
El presente art铆culo describe las tecnolog铆as de
informaci贸n y comunicaci贸n empleadas por las
cadenas de hipermercados y supermercados
familiares en Venezuela como una dimensi贸n
fundamental de la profesionalizaci贸n empresarial. El
dise帽o de investigaci贸n es no experimental de campo,
con un tipo de investigaci贸n descriptivo. Se aplic贸 un
cuestionario a los fundadores o sucesores de las
empresas familiares bajo estudio, las cuales no
pueden catalogarse como profesionalizadas
tecnol贸gicamente途 su evoluci贸n ha sido incipiente en
t茅rmino de propiciar la interconexi贸n con los
miembros de la cadena de valorThis article describes the information and
communications technologies used by the chains of
family hypermarkets and supermarkets in Venezuela
as a fundamental dimension of the business
professionalization. The research is descriptive, with
a non颅experimental research design of field. A
questionnaire was applied to the founders or
successors of the family companies in the study,
which cannot be classified as technologically
professionalized途 their evolution has been incipient in
order to facilitate the interconnection with members
of the value chain
Analysis of patterns in the university world rankings webometrics, Shanghai, QS and SIR-SCimago: case Latin America
The internationalization and positioning of universities offers relative comparisons, studied according to different teaching and research criteria. Among the recognized rankings are the Academic Ranking of World Universities (ARWU) or Ranking of Shanghai, QS World University Ranking, SCimago Institutions Rankings SIR and the Web Ranking of Universities-Webometrics. Comparatively, characteristics of each one are presented in terms of scope, volume of universities positioned and evaluation criteria. The indicators associated with research and institutional capacity stand out as common criteria in the revised evaluation methodologies. Regarding Latin America, Brazil leads with its presence in the four rankings. There is a greater number of Latin American universities in QS (40%) and Webometrics (31%), in the other two rankings it does not exceed 8%
Contextual factors that influence the entrepreneurship of family businesses in Venezuela
Este art铆culo constituye una reflexi贸n sobre aspectos contextuales que
inciden en el desarrollo del esp铆ritu emprendedor del empresario de car谩cter
familiar en Venezuela. La metodolog铆a se fundament贸 en el an谩lisis de fuentes
documentales. Los resultados develan que existen serias limitaciones que
disminuyen el dinamismo empresarial, como: regulaciones de precios, tipo de
cambio, marco jur铆dico laboral, excesivos tr谩mites administrativos y
deficiencias en los servicios p煤blicos. Frente a este escenario, existen
oportunidades que se derivan de la disminuci贸n de las importaciones, que han
dejado una demanda insatisfecha que posibilita la apertura de nuevas empresas
que deber谩n operar en condiciones de alta incertidumbre.This article is a reflection on contextual aspects that affect the
entrepreneurial spirit of the family entrepreneur in Venezuela. The
methodology was based on the analysis of documentary sources. The
results reveal that there are serious limitations that diminish the business
dynamism, such as: price regulations, exchange rate, labor legal
framework, excessive administrative procedures and deficiencies in public
services. Faced with this scenario, there are opportunities that are derived
from the decrease in imports, which have left an unmet demand that
allows the opening of new companies that must operate in conditions of
high uncertainty
Strategic direction in family businesses
La contribuci贸n de las empresas familiares al desarrollo
econ贸mico y aportes a la sociedad, fundamentan el
objetivo de analizar la efectividad de la direcci贸n
estrat茅gica en las empresas del sector servicios de
distribuci贸n y comercializaci贸n de tecnolog铆a en la
ciudad de Barranquilla. Metodol贸gicamente, responde a
una investigaci贸n de tipo descriptiva, dise帽o no
experimental de campo. Se determina la importancia de
minimizar los impactos t谩cticos y operativos que
afectan la sostenibilidad empresarial. Se recomienda,
lograr la efectividad de gesti贸n basada en la direcci贸n
estrat茅gica para superar las debilidades que presentan
al configurar la estructura organizacional con la
estrategia y el entornoThe contribution of family businesses to economic
development and contributions to society, are based on
the objective of analyzing the effectiveness of strategic
management in companies in the technology
distribution and marketing services sector in the city of
Barranquilla. Methodologically, it responds to a research
of descriptive type, non-experimental field design. The
importance of minimizing the tactical and operational
impacts that affect business sustainability is
determined. It is recommended to achieve management
effectiveness based on strategic direction to overcome
the weaknesses they present in shaping the
organizational structure with the strategy and the
environment
Measures of concentration and stability: two pedagogical tools for industrial organization courses
This document describes two pedagogical tools developed for teaching applied microeconomics, specifically the issues related to concentration, dominance, stability and asymmetry of firms. The tools make a compilation of several concentration and stability indexes used in the literature since 1945. Among the benefits of the applications are the ease and agility to perform comparative analyzes of intersectorial and/or intertemporal type in a simple and agile way; and the use of unconventional concentration and stability measures
Dividend decisions in family hypermarkets and supermarkets in Zulia State, Venezuela
Este art铆culo tiene como objetivo determinar la
injerencia de la familia sobre las decisiones de
dividendos aplicadas por las cadenas de hipermercados
y supermercados familiares en el estado Zulia,
Venezuela. El dise帽o de investigaci贸n es no
experimental de campo, con un tipo de estudio
descriptivo, mediante la aplicaci贸n de un cuestionario a
los propietarios o administradores de dichas empresas.
Los resultados muestran como la decisi贸n de dividendos
est谩 marcada por la cultura caracter铆stica de este tipo
de empresas, proclive a la reinversi贸n de beneficios,
siempre que no exista una demanda familiar con base
en sus necesidades que conlleve a la exigencia de
distribuci贸n de dividendos; por lo que se concluye que
la toma de decisiones es influida por la visi贸n y
comportamientos de los miembros de la familia propietaria de estas empresasThis article has as an objective to determine the
meddling of the family over the dividend decisions
applied by the chains of hypermarkets and family
supermarkets that are located in Zulia State, Venezuela.
The design of this investigation is of non-experimental
field, the study design is descriptive, by applying a
questionnaire to the owners or to the administrators of
these companies. Results show that dividend decisions
are characterized by the culture that these type of
companies have, prone to the reinvestment of the
incomes, as long as there is not a family demand based
in their necessities leading to dividend distribution; so
we can conclude that decision making is influenced by
the vision and behavior of the members of these family
owned companies
Corporative Government and Entrepreneurial Professionalization in Family Hypermarkets and Supermarkets in Venezuela
La empresa familiar es reconocida por su importante presencia en el mundo, caracterizada
por una estructura en la que se conjugan dos sistemas con l贸gicas distintas: la familia y la empresa;
raz贸n por la que uno de sus retos es lograr el balance entre los intereses y objetivos de la empresa y la
familia. El objetivo del presente art铆culo es describir el tipo de estructuras, planes y pol铆ticas de gobierno
corporativo con el que operan los hipermercados y supermercados familiares en Venezuela.
La investigaci贸n es no experimental de campo, con un tipo de estudio descriptivo, para lo que se utiliz贸
un cuestionario. Entre los principales resultados: a) en los hipermercados y supermercados familiares
las estructuras de gobierno formalizadas son las vinculadas al sistema de propiedad, y en contraposici贸n
se observa como las estructuras relacionadas con el sistema de familia son poco reconocidas e implementadas; b) la planificaci贸n de la empresa figura como una categor铆a escasamente
considerada y las pol铆ticas dise帽adas son las relacionadas a las estructuras implantadas; c) Las estructuras
de gobierno constituyen las plataformas para abordar y gestionar los aspectos relativos a
los sistemas familia, empresa y propiedad, de forma constructiva y por separado, evitando solapamientos,
o que siempre prime un sistema sobre el resto. Por ello, se concluye que se hace prioritario,
potenciar y/o establecer mecanismos efectivos de gobierno en los tres 谩mbitos.The family business is recognized for its significant presence in the world, characterized by a
structure in which two systems with different types of logic are joined: family and business. For this
reason, one of its challenges is to achieve a balance between the interests and objectives of the business
and the family. The objective of this article is to describe the type of structures, plans and policies
of corporative government with which family hyper and supermarkets operate in Venezuela. This is
non-experimental, field research with a descriptive type of study, for which a questionnaire was utilized.
The main results include: a) in family hyper and supermarkets, the formalized structures of government
are connected to the system of property, and in counter position, one can see how structures
related to the family system are little recognized and implemented; b) planning the business figures as
a category that is hardly considered, and the policies designed are related to the implanted structures;
c) government structures constitute the platforms for approaching and managing the aspects relative
to family, business and property systems, in a constructive manner and separately, avoiding overlapping
or that one system is always favored over the rest. For these reasons, conclusions are that it is a
priority to empower and/or establish effective government mechanisms in the three spheres
Dividend decisions in family hypermarkets and supermarkets in Zulia State, Venezuela
Este art铆culo tiene como objetivo determinar la
injerencia de la familia sobre las decisiones de
dividendos aplicadas por las cadenas de hipermercados
y supermercados familiares en el estado Zulia,
Venezuela. El dise帽o de investigaci贸n es no
experimental de campo, con un tipo de estudio
descriptivo, mediante la aplicaci贸n de un cuestionario a
los propietarios o administradores de dichas empresas.
Los resultados muestran como la decisi贸n de dividendos
est谩 marcada por la cultura caracter铆stica de este tipo
de empresas, proclive a la reinversi贸n de beneficios,
siempre que no exista una demanda familiar con base
en sus necesidades que conlleve a la exigencia de
distribuci贸n de dividendos; por lo que se concluye que
la toma de decisiones es influida por la visi贸n y
comportamientos de los miembros de la familia propietaria de estas empresas.This article has as an objective to determine the
meddling of the family over the dividend decisions
applied by the chains of hypermarkets and family
supermarkets that are located in Zulia State, Venezuela.
The design of this investigation is of non-experimental
field, the study design is descriptive, by applying a
questionnaire to the owners or to the administrators of
these companies. Results show that dividend decisions
are characterized by the culture that these type of
companies have, prone to the reinvestment of the
incomes, as long as there is not a family demand based
in their necessities leading to dividend distribution; so
we can conclude that decision making is influenced by
the vision and behavior of the members of these family
owned companies