Predicting uncertainty and risk in the natural sciences: bridging the gap between academics and industry

The increase in large-scale disasters in recent years, such as the 2007 floods in the UK, has caused disruptions of livelihood, enormous economic losses and increase in fatalities. Losses from natural hazards are only partially derived from the physical event itself but are also caused by society’s vulnerability to it. In the first three months of 2010, an unprecedented US$16 billion in losses occurred from natural hazards caused by events such as the Haiti and Chilean earthquakes, and the European storm Xynthia. This made it the worst ever first quarter for natural hazard losses and left the insurance industry exposed financially to the more loss-prone third and forth quarters. NERC science has a central role to play in the forecasting and mitigation of natural hazards. Research in this area forms the basis for technological solutions to early warning systems, designing mitigation strategies and providing critical information for decision makers to help save lives and avoid economic losses. Understanding uncertainty is essential if reliable forecasting and risk assessments are to be made. However, the quantification and assessment of uncertainty in natural hazards has in general been limited particularly in terms of model limitations and multiplicity. There are several reasons for this; most notably the fragmented nature of natural hazard research which is split both across science areas and between research, risk management and policy. Because of this, each sector has developed its own concepts and language which has acted as a barrier for effective communication and prevented the production of generic methods that have the potential to be used across sectors. It is clear therefore that by bringing the natural hazard community together significant breakthroughs in the visualisation and understanding of risk and uncertainty could be achieved. To accomplish this, this research programme has 4 prime objectives: 1.To improve communication and networking between researchers and risk managers within the financial services sector 2.To provide a platform for the dissemination of information on uncertainty and risk analysis between a range of researchers and practitioners 3.To generate a portfolio of best practice in uncertainty and risk analysis 4.To act as a focal point between the financial sector and natural hazard research in NERC This paper will discuss how the Natural Environmental Research Council, in partnership with other organisations such as TSB, EA and EPSRC etc, is working with academics and industry to bring about a step change in the way that uncertainty and risk assessments are achieved throughout the natural hazard community

Social Networks, Learning, and Flexibility: Sourcing Scientific Knowledge in New Biotechnology Firms

We examine how two highly successful new biotechnology firms (NBFs) source their most critical input -- scientific knowledge. We find that scientists at the two NBFs enter into large numbers of collaborative research efforts with scientists at other organizations, especially universities. Formal market contracts are rarely used to govern these exchanges of scientific knowledge. Our findings suggest that the use of boundary-spanning social networks by the two NBFs increases both their learning and their flexibility in ways that would not be possible within a self-contained hierarchical organization.

The Relationship of Selected Variables to Math Achievement in a Computer-Assisted Instructional Setting

The purpose of this study was to explore the variables of I.Q., sex, instructional organization, classroom instructional time, and time in computer-assisted instruction (CAI) in the third and fifth grades in order to determine which of these variables or combinations of variables were the best predictors of mathematics computation and concepts achievement. The study used a one-group pretest-posttest design

Ariel - Volume 2 Number 8

Editors Richard J. Bonanno Robin A. Edwards Associate Editors Steven Ager Stephen Flynn Shep Dickman Tom Williams Lay-out Editor Eugenia Miller Contributing Editors Michael J. Blecker Milton Packe James J. Nocon Lynne Porter Editors Emeritus Delvyn C. Case, Jr. Paul M. Fernhof

Ariel - Volume 2 Number 7

Editors Richard J. Bonanno Robin A. Edwards Associate Editors Steven Ager Stephen Flynn Shep Dickman Tom Williams Lay-out Editor Eugenia Miller Contributing Editors Michael J. Blecker W. Cherry Light James J. Nocon Lynne Porter Editors Emeritus Delvyn C. Case, Jr. Paul M. Fernhof

Ariel - Volume 2 Number 6

Editors Richard J. Bonanno Robin A. Edwards Associate Editors Steven Ager Stephen Flynn Shep Dickman Tom Williams Lay-out Editor Eugenia Miller Contributing Editors Michael J. Blecker W. Cherry Light James J. Nocon Lynne Porter Editors Emeritus Delvyn C. Case, Jr. Paul M. Fernhof

The Influence of Culture on Breast-Feeding Decisions by African American and White Women

Abstract: The purpose of this study was to examine how culture influenced breast-feeding decisions in African American and white women, using the Theory of Culture Care Diversity and Universality as a framework. One hundred eighty-six participants responded to the following: The word culture means beliefs and traditions passed down by your family and friends. How has culture affected how you plan to feed your baby? Qualitative content analysis was used to analyze the data. Four categories of responses were identified: influences of family, known benefits of breast-feeding, influences of friends, and personal choice. The findings suggest that race alone may not be as influential in infant feeding decisions as other factors. Although some women acknowledged the effect of their cultural background and experiences, most women reported that their culture did not affect their infant feeding decision. In this population, breastfeeding decisions were based on the influences of family, friends, self, and the perceived knowledge of breast-feeding benefits. Although breast-feeding statistics are commonly reported by race, cultural influences on infant feeding decisions may transcend race and include the influence of family and friends, learned information from impersonal sources, and information that is shared and observed from other people. Keywords: African American | Breast-feeding | White | Culture Article: Healthy People 2010 had 2 major goals: (a) increase the quality and years of healthy life and (b) eliminate health disparities. Increasing the proportion of mothers who initiate breast-feeding was one of the focus areas of Healthy People 2010 and it continues to be a focus in Healthy Peopl

The prevalence and origin of exoprotease-producing cells in the <em>Bacillus subtilis </em>biofilm

Biofilm formation by the Gram-positive bacterium Bacillus subtilis is tightly controlled at the level of transcription. The biofilm contains specialized cell types that arise from controlled differentiation of the resident isogenic bacteria. DegU is a response regulator that controls several social behaviours exhibited by B. subtilis including swarming motility, biofilm formation and extracellular protease (exoprotease) production. Here, for the first time, we examine the prevalence and origin of exoprotease-producing cells within the biofilm. This was accomplished using single-cell analysis techniques including flow cytometry and fluorescence microscopy. We established that the number of exoprotease-producing cells increases as the biofilm matures. This is reflected by both an increase at the level of transcription and an increase in exoprotease activity over time. We go on to demonstrate that exoprotease-producing cells arise from more than one cell type, namely matrix-producing and non-matrix-producing cells. In toto these findings allow us to add exoprotease-producing cells to the list of specialized cell types that are derived during B. subtilis biofilm formation and furthermore the data highlight the plasticity in the origin of differentiated cells

Functional specialization of duplicated AP3-like genes in Medicago truncatula

This is the accepted version of the following article: Roque, E., Serwatowska, J., Cruz Rochina, M., Wen, J., Mysore, K. S., Yenush, L., Beltrán, J. P. and Cañas, L. A. (2013), Functional specialization of duplicated AP3-like genes in Medicago truncatula. Plant J, 73: 663–675 , which has been published in final form at http://dx.doi.org/10.1111/tpj.12068The Bclass of MADS box genes has been studied in a wide range of plant species, but has remained largely uncharacterized in legumes. Here we investigate the evolutionary fate of the duplicated AP3-like genes of a legume species. To obtain insight into the extent to which B-class MADS box gene functions are conserved or have diversified in legumes, we isolated and characterized the two members of the AP3 lineage in Medicago truncatula: MtNMH7 and MtTM6 (euAP3 and paleoAP3 genes, respectively). A non-overlapping and complementary expression pattern of both genes was observed in petals and stamens. 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