Incarcerated Femoral Hernia

Careful analysis of 12 complicated cases of incarcerated femoral hernia gives clues toward the correct diagnosis of this problem. Knowledge of the symptoms can prevent dangerous delays in undertaking urgently-needed surgical repair. The unique anatomy involved requires careful clinical examination but surgery should not await x-ray studies

Echinococcosis of the Liver: Report of a Case

Echinococcosis of the liver is so rare in our practice that the case presented is the only one documented in the records of Henry Ford Hospital. The massive enlargement of the liver required surgical intervention. Marsupialization was the treatment of choice. In spite of post-operative complications, the patient made a satisfactory recovery

Posttraumatic Hernia of the Bladder

Fractures of the pelvis occur commonly in patients who are involved in high speed vehicle accidents or who fall from a substantial height. Fortunately, with improved surgical management, these patients usually recover not only from the pelvic fractures but from associated visceral injuries as well. Some survivors of pelvic fractures subsequently develop unusual hernias. We report the case of a man who developed hernia of the urinary bladder following pelvic fracture. Two previous operations had failed to eliminate his hernia. We describe the technique of repair used successfully in this case and review similar reported cases. Surgeons who care for traumatized patients must be alert to the possible presence of a pelvic fracture whenever pelvic laparotomy is performed for visceral injury. Reduction of the fracture and internal fixation are necessary to prevent posttraumatic hernia

Differentially expressed genes in a flock of Chinese local-breed chickens infected with a subgroup J avian leukosis virus using suppression subtractive hybridization

Avian leukosis virus subgroup J (ALV-J) is a new type of virus that mainly induces myeloid leukosis (ML) in chickens. To further elucidate the pathogenesis of ALV-J infection and tumor development, expression profiles from the bone marrow tissue of 15 infected and 18 non-infected birds from a local-breed poultry-farm under naturally infected conditions, were analyzed by suppression-subtractive hybridization. The birds were diagnosed as ML+ (or ML-) by specific ALV-J detection methods, involving serological tests for antigens and antibodies, and RT-PCR to detect viral RNA. A total of 59 partial gene sequences were revealed by differential screening of 496 forward and 384 reverse subtracted cDNA clones. Of these, 22 identified genes, including 8 up-regulated and 14 down-regulated, were related to immune functions, these genes being, MHC B-G antigen, translationally-controlled tumor protein (TPT1/TPTC), transferrin and ferritin, hemoglobin and Carbonic anhydrase. Four of the down-regulated genes were selected for further analysis, in view of their predicted roles in infection and immunity by real-time qRT-PCR, using RNA collected from the same birds as those used for SSH. The four genes were expressed at significantly lower levels (p < 0.001) in ALV-J infected birds than in non-infected ones