CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research

Stacking Ensemble Methodology Using Deep Learning and ARIMA Models for Short-Term Load Forecasting

Short-Term Load Forecasting is critical for reliable power system operation, and the search for enhanced methodologies has been a constant field of investigation, particularly in an increasingly competitive environment where the market operator and its participants need to better inform their decisions. Hence, it is important to continue advancing in terms of forecasting accuracy and consistency. This paper presents a new deep learning-based ensemble methodology for 24 h ahead load forecasting, where an automatic framework is proposed to select the best Box-Jenkins models (ARIMA Forecasters), from a wide-range of combinations. The method is distinct in its parameters but more importantly in considering different batches of historical (training) data, thus benefiting from prediction models focused on recent and longer load trends. Afterwards, these accurate predictions, mainly the linear components of the load time-series, are fed to the ensemble Deep Forward Neural Network. This flexible type of network architecture not only functions as a combiner but also receives additional historical and auxiliary data to further its generalization capabilities. Numerical testing using New England market data validated the proposed ensemble approach with diverse base forecasters, achieving promising results in comparison with other state-of-the-art methods

Controller Design and Experimental Validation of A Solar Powered E-bike Charging Station

Electric Vehicles (EV) have gained interest over the past decade. Because of this, to support EV technology installation of charging stations are required. Charging EVs from renewable energy provides a sustainable means of transport. E-bikes can help mitigate some mobility problems, particularly in large cities and metropolitan areas. This paper shows the development and implementation of a solar e-bike charging station with photovoltaic production, with energy storage system. The implemented system has a centralized control and allow an efficient management of the various resources and contemplates the possibility of four simultaneous e- bikes where user identification is performed by RFID. Finally, it is provided a user interface through an HMI panel and a web page where it will be possible to access the DataLog to consult the user activity and all charging parameters. Keywords: Renewable energy, Solar charging station, Programmable logic controller &nbsp