Approaches to Assessing the Demand for Vocational Education

The article discusses the prospects for the development of regional systems of secondary vocational education (on the basis of basic general education) through the prism of assessing the demand for secondary vocational education and covering this level of education in the context of demography and competition from schools Keywords: secondary vocational education, demand for education, educational coverage, private educational organizations, regional education system

The Need for Regional Labor Markets for Mid-Level Specialists and the Priorities of Graduates of Secondary Vocational Education in Employment Issues

The article considers the problems of imbalance of supply and demand in regional labor markets, as well as the role of career guidance in choosing a profession. The article discloses the main management decisions for regulating reception targets, taking into account labor market requirements. The authors give examples of calculating the imbalance of supply and demand in personnel in regional labor markets using the example of the region’s need for mid-level medical workers. The article considers the aspects of employment of graduates of professional educational organizations, including labor migration and international experience. As a result of the study, the authors identified and formulated the general laws of labor migration of graduates of professional educational organizations and solutions to reduce the outflow of labor resources from the region. Separately, the authors examined the employment of graduates of the SVE (secondary vocational education) system in Moscow and St. Petersburg. The article was completed within the framework of the topic of the State Task of the RANEPA N 11.5 “Study of models for the transformation of regional systems of secondary vocational education and their need for resource support” for 2021

ОБРАЗОВАТЕЛЬНЫЕ АЛЬЯНСЫ ЕВРОПЕЙСКОГО СОЮЗА И ЕВРАЗИЙСКОГО ЭКОНОМИЧЕСКОГО СОЮЗА: СОСТОЯНИЕ И ПЕРСПЕКТИВЫ РАСШИРЕНИЯ

The article is devoted to interstate educational space EU, EEU: describe the mechanisms for their establishment and highlighted their main characteristics. Russia has become a party at different times of all of that interstate educational spaces. . Given the fact that the humanitarian cooperation in the field of education has economic consequences, measured in concrete terms, the article analyzed the capacity of pro-labor market of highly qualified personnel (labor mobility) and the educational market (academic mobility) countries participating in intergovernmental alliances. The authors concluded that the trend of the growth of regionalization of education, as evidenced, in particular, the growing regional academic and labor mobility. Moreover, if the foundations for the EU-governmental regional centers of education were Germany and France, for the EEU – Russia. For Russia, for the first time facing the challenge of working on the reduction-settlement, participation in international educational alliances can bring additional dividends if the solution to this problem will go the way of increasing labor migration and training of the participating countries of the EEU. In this case, Existing-exists the need for correction of the state policy in the field of attracting highly qualified you are, foreign experts and training issues for foreign countries.Статья посвящена межгосударственным образовательным пространствам ЕвропейскогоСоюза и Евразийского Экономического Союза: описаны механизмы их создания и выделены их основные характеристики. Россия стала в разное время участницей всех перечисленных образовательных пространств. С учетом того, что гуманитарное сотрудничество в области образования имеет экономические последствия, измеряемые в конкретных показателях, в статье проанализированы емкости рынка труда высококвалифицированных кадров (трудовая мобильность) и образовательного рынка (академическая мобильность) стран-участниц межгосударственных альянсов. Авторами сделан вывод о нарастании тенденции регионализации образования, о чем свидетельствуют, прежде всего, возрастающие потоки региональной академической и трудовой мобильности. Причем, если для Европейского Союза основными региональными центрами образования стали Германия и Франция, то для Евразийского Экономического Союза – Россия. Для России, впервые стоящей перед проблемой сокращения трудоспособного населения, участие в межгосударственных образовательных альянсах может принести дополнительные дивиденды, если решение этой проблемы пойдет по пути увеличения трудовой и учебной миграции из стран-участниц Евразийского Экономического Союза. В этом случае существует необходимость коррекции государственной политики в области привлечения высококвалифицированных зарубежных специалистов и вопросы подготовки кадров для зарубежных государств

ПРЕДВАРИТЕЛЬНЫЕ РЕЗУЛЬТАТЫ ИСПОЛЬЗОВАНИЯ ФТОРАФУРА В КОМБИНАЦИИ С ИРИНОТЕКАНОМ И ОКСАЛИПЛАТИНОМ У ПАЦИЕНТОВ С РАСПРОСТРАНЕННЫМ КОЛОРЕКТАЛЬНЫМ РАКОМ

Objective: to develop an effective, well-tolerated, convenient for outpatient care (without installing a subclavian catheter) three-component treatment regimen that includes ftorafur – an original oral fluoropyrimidine drug.Materials and methods. The study included 25 patients with disseminated colorectal cancer that have never received specific pharmacotherapy. We evaluated the efficacy and safety of a new first-line three-component treatment regimen with oxaliplatin + irinotecan + ftorafur. Patients in group 1 (n = 6) received this regimen for 3 weeks, whereas patients in group 2 (n = 19) received it for 2 weeks.Results. Only preliminary results of the study are currently available. Median time to progression and overall survival are not yet estimated. Three (50 %) patients from group 1 achieved partial regression of metastases; 3 patients from this group had long-term (≥6 months) disease stabilization. Therapeutic effect (partial remission + long-term stabilization) was observed in all patients. Time without progression varied between 6 and 20 months. In group 2, therapeutic effect was estimated in 18 patients that received at least 2 courses of chemotherapy. Eight out of these 18 patients had partial response (2 of them underwent radical surgery); 8 patients had disease stabilization. Thus, 88.8 % of patients from group 2 responded to treatment. In the whole study population (both groups), response to treatment was achieved in 91 % of patients.Conclusion. Our preliminary results suggest that the combination of oxaliplatin, irinotecan and ftorafur is safe and has an acceptable toxicity profile; therefore, it can be used in weakened patients.Цель исследования – разработка удобного для амбулаторной практики (без необходимости установки подключичного порта), хорошо переносимого и эффективного трехкомпонентного режима, включающего пероральный оригинальный препарат фторпиримидинового ряда фторафур.Материалы и методы. В исследование были включены 25 пациентов с распространенным колоректальным раком, не получавших ранее специфического лекарственного лечения, у которых в 1-й линии лечения оценены эффективность и безопасность нового трехкомпонентного режима иринотекан + оксалиплатин + фторафур. В 1-й группе пациентов (n = 6) был применен 3-недельный режим химиотерапии, во 2-й группе (n = 19) – 2-недельный.Результаты. В настоящее время получены предварительные результаты. Медианы времени до прогрессирования и общей выживаемости не достигнуты. В 1-й группе частичная регрессия метастазов достигнута у 3 (50 %) пациентов, длительная (≥6 мес) стабилизация болезни отмечена еще у 3 пациентов. Лечебный эффект (частичная ремиссия + длительная стабилизация) отмечен у всех пациентов. Время без прогрессирования составляло от 6 до 20 мес. Во 2-й группе эффект оценен у 18 пациентов, получивших как минимум 2 курса химиотерапии. У 8 из 18 пациентов отмечен частичный ответ (из них 2 пациента были радикально прооперированы), у 8 наблюдалась стабилизация болезни. Таким образом, во 2-й группе ответ на лечение достигнут у 88,8 % пациентов. Суммарный ответ на лечение в обеих группах составил 91 %.Выводы. Предварительные данные могут свидетельствовать о том, что комбинация оксалиплатина, иринотекана и фторафура является эффективной, имеет приемлемый профиль токсичности и может быть использована у ослабленных пациентов

Functional constipation during and after pregnancy

Functional constipation is a common problem in pregnancy and postpartum period and is now considered not just a medical problem but also a factor influencing the quality of life. The frequency of defecation differs in people. Recent years specialists prefer personalized evaluation of the frequency of defecation for exact diagnostics of the condition, but not the classic definition. Functional constipation in pregnancy is caused by functional and anatomy changes of gastrointestinal tract and also by hormonal changes in pregnancy. Early diagnosis and correction of this pathology is one of the main objectives when managing normal pregnancy. This review covers current information on the theme, contains recommendations about the lifestyle during pregnancy and postpartum period and treatment options. Some foreign and Russian authors note the effectiveness of sodium picosulfate which accelerates the passage of the feces in a short time. It can be used during II and III trimesters of pregnancy as well as in the postpartum period and breastfeeding. Thus, complex correction of factors causing functional constipation decreases the risk of colon diseases as well as of all gastrointestinal tract in pregnant women and in the puerperium

Development of the system of continuous education in Netherlands: state and prospects

An article focuses on the experiences of Netherlands VET in Europe

INTERSTATE EDUCATIONAL SPACE OF EU AND CIS

The article is devoted to interstate educational space EU, CIS: describe the mechanisms for their establishment and highlighted their main characteristics. Russia has become a party at different times of all of that interstate educational spaces. Given the fact that the humanitarian cooperation in the field of education has economic consequences, measured in concrete terms, the article analyzed the capacity of pro-labor market of highly qualified personnel (labor mobility) and the educational market (academic mobility) countries participating in intergovernmental alliances. The authors concluded that the trend of the growth of regionalization of education, as evidenced, in particular, the growing regional academic and labor mobility. Moreover, if the foundations for the EU-governmental regional centers of education were Germany and France, for the CIS - Russia.For Russia, for the first time facing the challenge of working on the reduction-settlement, participation in international educational alliances can bring additional dividends if the solution to this problem will go the way of increasing labor migration and training of the participating countries of the CIS. In this case, Existing-exists the need for correction of the state policy in the field of attracting highly qualified you are, foreign experts and training issues for foreign countries

Education alliance European Union and Eurasian Economic Union: status and prospects of expansion

The article is devoted to interstate educational space EU, EEU: describe the mechanisms for their establishment and highlighted their main characteristics. Russia has become a party at different times of all of that interstate educational spaces. . Given the fact that the humanitarian cooperation in the field of education has economic consequences, measured in concrete terms, the article analyzed the capacity of pro-labor market of highly qualified personnel (labor mobility) and the educational market (academic mobility) countries participating in intergovernmental alliances. The authors concluded that the trend of the growth of regionalization of education, as evidenced, in particular, the growing regional academic and labor mobility. Moreover, if the foundations for the EU-governmental regional centers of education were Germany and France, for the EEU – Russia. For Russia, for the first time facing the challenge of working on the reduction-settlement, participation in international educational alliances can bring additional dividends if the solution to this problem will go the way of increasing labor migration and training of the participating countries of the EEU. In this case, Existing-exists the need for correction of the state policy in the field of attracting highly qualified you are, foreign experts and training issues for foreign countries

The role of dydrogesterone in habitual miscarriage

Habitual miscarriage is a fairly common complication of early pregnancy. In the opinion of most authors, the term habitual miscarriage is used to describe a loss of two or more pregnancies during the first 22 weeks of pregnancy. Issues of terminology and management continue to be relevant and debatable in medical professional communities and need further discussion. In addition to the medical sides of the issue, habitual miscarriage has a significant psychological impact on women and their partners. Regardless of the gestational age, the loss of pregnancy for most couples is similar in importance to the loss of a newborn and is associated with the loss of hope and plans that future parents connected with a baby who has not yet been born. After repeated losses, bereavement and emotional upheaval are further exacerbated irrespective of the term of abortion. Repeated pregnancy loss is a significant negative event in the life of a couple both from a medical and psychological point of view, that’s why the provision of adequate medical care is one of the objectives of a specialist managing pregnancy. This also involves the choice of effective disease management. Previously it was shown that luteal phase deficiency might be the cause of this phenomenon, and that hormonal deficiency had to be replenished. Many modern publications confirm that progesterone and its derivatives have an important immunomodulatory role in the habitual miscarriage. The article describes the role of progesterone in maintaining pregnancy and the results of studies devoted to the role of dydrogesterone. It also presents data of international studies on the treatment of women with habitual miscarriage