1902 Polk\u27s Medical Register and Directory of the United States and Canada (Texas portion only)

List of Physicians and Surgeons arranged by states and provinces, giving post office address with population and location, the School practiced, date and college of graduation, all the existing and extinct medical colleges in the United States and Canada, with locations, officers, number of professors, lecturers, demonstrators, etc., the various medical societies, state prisons, hospitals, sanitariums, dispensaries, asylums and other medical institutions, boards of health, boards of medical examiners, a synopsis of the laws of registration and other laws relating to the profession, medical journals with names of editors, frequency of publication and subscription rates, medical libraries, mineral springs, official list of officers of the medical departments of the U.S. Army, Navy and Marine Hospital Service, roster of examining surgeons of the U.S. Pension Department, a descriptive sketch of each state, territory and province, embodying such matters as location, boundary, extent in miles and acres, latitude and longitude, statistics relating to climate, temperature, rate of mortality, number of deaths from consumption, etc. full particulars of all national associations and societies relating to medicine and surgery, and an INDEX TO THE PHYSICIANS OF THE UNITED STATES. Arranged alphabetically, with the number of the page on which the name appears.https://digitalcommons.library.tmc.edu/ebooks/1008/thumbnail.jp

New insights into the genetic etiology of Alzheimer's disease and related dementias

Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele

R L Polk Tiffin City and Seneca County Directory 1911-1912

R.L. Polk's Tiffin City and Seneca County Directory for the years 1911 to 1912 contains lists of names, occupations, and addresses of residents, as well as a list of businesses, city and county government officials, schools, churches, cemeteries, banks, parks, secret and benevolent societies. It was published by R.L. Polk and Company, 85 North High Street, Columbus, Ohio

R. L. Polk & Co.'s Sherman City Directory, 1910-1911

The directory for Sherman, Texas includes address listings for businesses and individuals as well as advertisements from local businesses. According to the title page, the directory contains "a complete alphabetical list of business firms and private citizens of Sherman. A miscellaneous directory of city and county officials, churches, public and private schools, banks, asylums, hospitals and homes, commercial, bodies, secret societies, street and avenue guide, etc., etc., etc. Also a Complete Classified Business Directory and Numerical Street Directory." Indexes to content are on page 10; index to advertisers is on page 12