Improving the Acoustic Performance of Linear Multi-Element Transducers

The electro-acoustic performance of transducers has a direct impact on the performance of ultrasound inspections. The signal/noise ratio and the resolution (both axial and lateral) are key factors for detecting and/or proportioning the indications being sought. The signal/noise ratio partly depends on the sensitivity and the signal/noise ratio of the transducer itself. The axial resolution depends on the length of the signal and therefore, for a given maximum frequency, on the damping of the transducer. Sensitivity and damping are often considered antagonistic, as damping traditionally reduces resonance and therefore sensitivity. Earlier studies have demonstrated the advantages gained through using piezocomposite technology to improve this compromise. These two parameters also depend on the acoustic adaptation to the coupling medium (water, plexiglass, rexolite, steel, etc.), and according to the design used, performance deteriorates more or less as one moves further from the nominal use. In addition to sensitivity and the signal/noise ratio, other parameters such as the angular acceptance and resistance to abrasion are sometimes to be integrated in the expected performances. This article presents the recent developments undertaken and tested in the context of improving the acoustic performance of multi-element probes: - Identification of the components that influence performance; - Simulations; - Selection of the configurations that meet the needs of various applications; - The experimental results obtained; - Comparison with the simulations. These studies have led to the development of a design expertise for responding to requests for custom-made, industrial, multi-element probes with improved performance, for production runs from a single item to dozens, even hundreds. The detailed results will be presented, as well as the possibilities for future development

Flexible Wedge Phased Array Transducers for Inspecting Variable-Geometry or Complex Components

The transmission of ultrasound from the transducer into the inspected component is a determining factor in the performance of ultrasound inspections. Various coupling solutions exist to ensure this transmission. The most frequently used are:• Immersion of the component in water tank: This coupling presents the best acoustic performance (low attenuation, coupling homogeneity, no intermediate interface). However, the inspected parts need to be fully immersed and thus complex control systems are required.• Coupling by direct contact with a liquid couplant, or via a rigid wedge or a delay line with liquid couplant at the interfaces: This coupling requires simpler control systems for the inspection, but the homogeneity of the couplant film and attenuation in the wedges deteriorate the signal. The geometry of the inspected part can make the coupling more difficult to setup, particularly if the surface is complex or varies from one point to another. The problem becomes critical when the dimensions of the transducer are large in comparison with the local curvature of the interface. The use of transducers that are flexible, or that are fitted with a flexible wedge, improves the quality of the coupling for components with complex or variable geometry, and in some cases, makes it possible to do certain inspections that currently have no solution. This article presents the recent developments and results obtained in the context of transducers with flexible wedges, in particular: • Design options; • Flexible membranes and mechanical interfaces development for PA transducers; • Mechanical supports development for manual or automated use; • Acoustic performance, and wear resistance tests; These studies have demonstrated the contribution of flexible wedge transducers to various applications, with acoustic performances similar to that of immersion and easy implementation comparable to standard contact inspections, while remaining compatible with an industrial use. The detailed results will be presented, as well as the possibilities for the future developments of transducers with flexible wedges

Genome-Wide Search Reveals the Existence of a Limited Number of Thyroid Hormone Receptor Alpha Target Genes in Cerebellar Neurons

Thyroid hormone (T3) has a major influence on cerebellum post-natal development. The major phenotypic landmark of exposure to low levels of T3 during development (hypothyroidism) in the cerebellum is the retarded inward migration of the most numerous cell type, granular neurons. In order to identify the direct genetic regulation exerted by T3 on cerebellar neurons and their precursors, we used microarray RNA hybridization to perform a time course analysis of T3 induced gene expression in primary cultures of cerebellar neuronal cell. These experiments suggest that we identified a small set of genes which are directly regulated, both in vivo and in vitro, during cerebellum post-natal development. These modest changes suggest that T3 does not acts directly on granular neurons and mainly indirectly influences the cellular interactions taking place during development

Flexible Wedge Phased Array Transducers for Inspecting Variable-Geometry or Complex Components

The transmission of ultrasound from the transducer into the inspected component is a determining factor in the performance of ultrasound inspections. Various coupling solutions exist to ensure this transmission. The most frequently used are:• Immersion of the component in water tank: This coupling presents the best acoustic performance (low attenuation, coupling homogeneity, no intermediate interface). However, the inspected parts need to be fully immersed and thus complex control systems are required.• Coupling by direct contact with a liquid couplant, or via a rigid wedge or a delay line with liquid couplant at the interfaces: This coupling requires simpler control systems for the inspection, but the homogeneity of the couplant film and attenuation in the wedges deteriorate the signal. The geometry of the inspected part can make the coupling more difficult to setup, particularly if the surface is complex or varies from one point to another. The problem becomes critical when the dimensions of the transducer are large in comparison with the local curvature of the interface. The use of transducers that are flexible, or that are fitted with a flexible wedge, improves the quality of the coupling for components with complex or variable geometry, and in some cases, makes it possible to do certain inspections that currently have no solution. This article presents the recent developments and results obtained in the context of transducers with flexible wedges, in particular: • Design options; • Flexible membranes and mechanical interfaces development for PA transducers; • Mechanical supports development for manual or automated use; • Acoustic performance, and wear resistance tests; These studies have demonstrated the contribution of flexible wedge transducers to various applications, with acoustic performances similar to that of immersion and easy implementation comparable to standard contact inspections, while remaining compatible with an industrial use. The detailed results will be presented, as well as the possibilities for the future developments of transducers with flexible wedges.</p

Improving the Acoustic Performance of Linear Multi-Element Transducers

The electro-acoustic performance of transducers has a direct impact on the performance of ultrasound inspections. The signal/noise ratio and the resolution (both axial and lateral) are key factors for detecting and/or proportioning the indications being sought. The signal/noise ratio partly depends on the sensitivity and the signal/noise ratio of the transducer itself. The axial resolution depends on the length of the signal and therefore, for a given maximum frequency, on the damping of the transducer. Sensitivity and damping are often considered antagonistic, as damping traditionally reduces resonance and therefore sensitivity. Earlier studies have demonstrated the advantages gained through using piezocomposite technology to improve this compromise. These two parameters also depend on the acoustic adaptation to the coupling medium (water, plexiglass, rexolite, steel, etc.), and according to the design used, performance deteriorates more or less as one moves further from the nominal use. In addition to sensitivity and the signal/noise ratio, other parameters such as the angular acceptance and resistance to abrasion are sometimes to be integrated in the expected performances. This article presents the recent developments undertaken and tested in the context of improving the acoustic performance of multi-element probes: - Identification of the components that influence performance; - Simulations; - Selection of the configurations that meet the needs of various applications; - The experimental results obtained; - Comparison with the simulations. These studies have led to the development of a design expertise for responding to requests for custom-made, industrial, multi-element probes with improved performance, for production runs from a single item to dozens, even hundreds. The detailed results will be presented, as well as the possibilities for future development.</p

Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TR alpha gene

Mice devoid of all TRs are viable, whereas Pax8(-/-)mice, which lack the follicular cells producing T-4 and T-3 in the thyroid gland, die during the first weeks of postnatal life. A precise comparison between the two types of mutants reveals that their phenotypes are similar, but the defects in spleen, bone, and small intestine are more pronounced in Pax(-/-) mice. This is interpreted as the result of a negative effect of the unliganded TR on thyroid hormone target genes expression in the Pax(-/-)mutants. Pax8(-/-) compound mutants can survive to adulthood, and the expression of target genes is partially restored. This demonstrates the importance of TR alpha aporeceptor activity in several aspects of postnatal development