44 research outputs found
Defect-induced magnetism in graphite through neutron irradiation
We have investigated the variation in the magnetization of highly ordered
pyrolytic graphite (HOPG) after neutron irradiation, which introduces defects
in the bulk sample and consequently gives rise to a large magnetic signal. We
observe strong paramagnetism in HOPG, increasing with the neutron fluence. We
correlate the induced paramagnetism with structural defects by comparison with
density-functional theory calculations. In addition to the in-plane vacancies,
the trans-planar defects also contribute to the magnetization. The lack of any
magnetic order between the local moments is possibly due to the absence of
hydrogen/nitrogen chemisorption, or the magnetic order cannot be established at
all in the bulk form.Comment: 10 pages, 8 figure
3-ALKENYL INDOLES AS TRYPTOPHAN 2,3-DIOXYGENASE INHIBITORS FOR THE ENHANCEMENT OF CANCER IMMUNOTHERAPY
3-ALKENYL INDOLES AS TRYPTOPHAN 2,3-DIOXYGENASE INHIBITORS FOR THE ENHANCEMENT OF CANCER IMMUNOTHERAPY
STAR-Fusion: Fast and Accurate Fusion Transcript Detection from RNA-Seq
Motivation Fusion genes created by genomic rearrangements can be potent drivers of tumorigenesis. However, accurate identification of functionally fusion genes from genomic sequencing requires whole genome sequencing, since exonic sequencing alone is often insufficient. Transcriptome sequencing provides a direct, highly effective alternative for capturing molecular evidence of expressed fusions in the precision medicine pipeline, but current methods tend to be inefficient or insufficiently accurate, lacking in sensitivity or predicting large numbers of false positives. Here, we describe STAR-Fusion, a method that is both fast and accurate in identifying fusion transcripts from RNA-Seq data.
Results We benchmarked STAR-Fusion’s fusion detection accuracy using both simulated and genuine Illumina paired-end RNA-Seq data, and show that it has superior performance compared to popular alternative fusion detection methods.
Availability and implementation STAR-Fusion is implemented in Perl, freely available as open source software at http://star-fusion.github.io, and supported on Linux
Le projet expérimental multidisciplinaire (PEMD) en 3ème Bachelier à Gembloux
Cette courte présentation, dans l'atelier 3 du colloque ILIB15, décrit l'intégration d'un cours (« littérature scientifique et méthodologie documentaire »), dont le titulaire est un bibliothécaire, dans une unité d’apprentissage intégrée basée sur la résolution d'un problème concret de recherche dans un contexte scientifique non familier. Ce cours a été proposé pour la première fois durant l'année académique 2014-2015 à une partie des étudiants du bloc trois du Master Bioingénieur, orientation Sciences et technologies de l’environnement de l'Université de Liège. Cette activité se déroule en plusieurs phases sur les deux quadrimestres
Le programme expérimental multidisciplinaire à Gembloux, retour d'expérience
Presentation of a collective course at Gembloux Agro-Bio Tech : the multidisciplinary experimental progra
Estimation de l’âge au décès d’individus du Néolithique de la grotte-abri du Tiène-des-Maulins (Rochefort, province de Namur) par l’analyse de la microstructure osseuse.
info:eu-repo/semantics/nonPublishe