The self-organizing fractal theory as a universal discovery method: the phenomenon of life

A universal discovery method potentially applicable to all disciplines studying organizational phenomena has been developed. This method takes advantage of a new form of global symmetry, namely, scale-invariance of self-organizational dynamics of energy/matter at all levels of organizational hierarchy, from elementary particles through cells and organisms to the Universe as a whole. The method is based on an alternative conceptualization of physical reality postulating that the energy/matter comprising the Universe is far from equilibrium, that it exists as a flow, and that it develops via self-organization in accordance with the empirical laws of nonequilibrium thermodynamics. It is postulated that the energy/matter flowing through and comprising the Universe evolves as a multiscale, self-similar structure-process, i.e., as a self-organizing fractal. This means that certain organizational structures and processes are scale-invariant and are reproduced at all levels of the organizational hierarchy. Being a form of symmetry, scale-invariance naturally lends itself to a new discovery method that allows for the deduction of missing information by comparing scale-invariant organizational patterns across different levels of the organizational hierarchy

Stabilization of metastable hydrogen trioxide (HOOOH) and the hydrotrioxyl radical (HOOOradical dot) by complexation with sulfuric acid. A theoretical study

The formation of bimolecular complexes of HOOOH and the HOOOﰀ radical with sulfuric acid (H2SO4– HOOOH, H2SO4–HOOOﰀ) has been investigated by using DFT (B3LYP/6-311++G(3df,3pd)) and CCSD(T)- F12 methods. For the first time the structures and the binding energies (BEs) for the various isomeric hydrogen-bonded complexes have been reported. The results reveal an unusually stable H2SO4–HOOOH eight-membered ring structure with two relatively strong hydrogen bonds, and with a calculated BE (CCSD(T)-F12) of 12.7 kcal molﰁ1. This is equivalent to the BE in the H2SO4–HOOH complex investigated at the same theoretical level. The complexation of HOOOﰀ with H2SO4 stabilizes this metastable polyoxide intermediate by about 10.0 kcal molﰁ1

Genetic Variability in CYP2E1 and Catalase Gene Among Currently and Formerly Alcohol-Dependent Male Subjects

International audienceRapport 2018 de l'Autorité des marchés financiers sur le gouvernement d'entreprise et la rémunération des dirigeants, 26 nov. 201