Impact of the COVID-19 pandemic on contact tracing of patients with pulmonary tuberculosis

Background: The COVID-19 pandemic could have negative effects on tuberculosis (TB) control. The objective was to assess the impact of the pandemic in contact tracing, TB and latent tuberculosis infection (LTBI) in contacts of patients with pulmonary TB in Catalonia (Spain). Methods: Contact tracing was carried out in cases of pulmonary TB detected during 14 months in the pre-pandemic period (1 January 2019 to 28 February 2020) and 14 months in the pandemic period (1 March 2020 to 30 April 2021). Contacts received the tuberculin skin test and/or interferon gamma release assay and it was determined whether they had TB or LTBI. Variables associated with TB or LTBI in contacts (study period and sociodemographic variables) were analyzed using adjusted odds ratio (aOR) and the 95% confidence intervals (95% CI). Results: The pre-pandemic and pandemic periods showed, respectively: 503 and 255 pulmonary TB reported cases (reduction of 50.7%); and 4676 and 1687 contacts studied (reduction of 36.1%). In these periods, the proportion of TB cases among the contacts was 1.9% (84/4307) and 2.2% (30/1381) (P = 0.608); and the proportion of LTBI was 25.3% (1090/4307) and 29.2% (403/1381) (P < 0.001). The pandemic period was associated to higher LTBI proportion (aOR = 1.3; 95% CI 1.1–1.5), taking into account the effect on LTBI of the other variables studied as sex, age, household contact and migrant status. Conclusions: COVID-19 is affecting TB control due to less exhaustive TB and LTBI case detection. An increase in LTBI was observed during the pandemic period. Efforts should be made to improve detection of TB and LTBI among contacts of TB cases.This study was supported by the Ministry of Science and Innovation, Institute of Health Carlos III (Project PI18/01751) and Fondo Europeo de Desarrollo Regional (FEDER-Una manera de hacer Europa)

Design of a UMTS/GPRS Assisted Mesh Network (UAMN)

Wireless Mesh or multi-hop networks (WMNs) are well known thanks to its simplicity on deployment and the lack of infrastructure. These two advantages come with some drawbacks. WMNs have limitations with the support of Quality of Service (QoS), they do not assure coverage or even connectivity, and security, management and monitoring are not considered key requirements. In order to benefit of mesh networks and use them as an operator graded network, it is necessary to either improve mesh networks to fulfill all these requirements or use an alternative network that offers full availability, connectivity and security to assist the mesh network. Considering the two options, the second is the one selected making use of GPRS/UMTS as an assistant network. The document describes a set of requirements and the design of the functionalities needed to build an operator graded network using the cellular GPRS/UMTS. The aspects covered in the design are: security, quality of service, mobility, self configuration and optimization. The last point, optimization, is not directly involved with mesh networking, but it is an improvement easy to achieve when using a gateway node to access the Internet through a GPRS/UMTS connection. The design of the solution not only considers functionality, but also feasibility employing of the shelve elements. The mesh nodes and gateways are built on top of Linux operating system with the aim to reuse previous results and open source software. The final objective of the project is to build a usable system to be used as a proof of concept.Peer Reviewe

Design of a UMTS/GPRS Assisted Mesh Network (UAMN)

Wireless Mesh or multi-hop networks (WMNs) are well known thanks to its simplicity on deployment and the lack of infrastructure. These two advantages come with some drawbacks. WMNs have limitations with the support of Quality of Service (QoS), they do not assure coverage or even connectivity, and security, management and monitoring are not considered key requirements. In order to benefit of mesh networks and use them as an operator graded network, it is necessary to either improve mesh networks to fulfill all these requirements or use an alternative network that offers full availability, connectivity and security to assist the mesh network. Considering the two options, the second is the one selected making use of GPRS/UMTS as an assistant network. The document describes a set of requirements and the design of the functionalities needed to build an operator graded network using the cellular GPRS/UMTS. The aspects covered in the design are: security, quality of service, mobility, self configuration and optimization. The last point, optimization, is not directly involved with mesh networking, but it is an improvement easy to achieve when using a gateway node to access the Internet through a GPRS/UMTS connection. The design of the solution not only considers functionality, but also feasibility employing of the shelve elements. The mesh nodes and gateways are built on top of Linux operating system with the aim to reuse previous results and open source software. The final objective of the project is to build a usable system to be used as a proof of concept.Peer Reviewe