19 research outputs found

    Use of anticoagulants and antiplatelet agents in stable outpatients with coronary artery disease and atrial fibrillation. International CLARIFY registry

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    Effectiveness of the Combined Recombinant Human Growth Hormone and Gonadotropin-Releasing Hormone Analog Therapy in Pubertal Patients with Short Stature due to SHOX Deficiency

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    Context: Isolated heterozygous SHOX defects are the most frequent monogenic cause of short stature, and combined therapy with recombinant human GH (rhGH) and GnRH analog (GnRHa) in pubertal patients has been suggested, but there are no data on final height

    Boas pråticas de ordenha na propriedade familiar para obtenção de leite e queijo artesanal de qualidade : cartilhas elaboradas conforme metologia e-Rural.

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    A ordenha Ă© uma das tarefas mais importantes em uma propriedade leiteira, pois Ă© o momento em que o produtor obtĂ©m o principal produto de sua atividade: o leite. Uma boa ordenha Ă© essencial para se obter leite de maneira rĂĄpida, higiĂȘnica e sem causar lesĂ”es nos tetos ou espalhar doenças entre as vacas. O objetivo desta cartilha Ă© mostrar como melhorar a qualidade do leite para produção do queijo artesanal, assim como seu rendimento, utilizando as boas prĂĄticas no sistema de ordenha manual ou mecĂąnica tipo latĂŁo ao pĂ© mais conhecido como balde ao pĂ©.bitstream/item/170535/1/Cartilha-Boas-Praticas-de-ordenha.pd

    The crosscutting impact of the AOSD Brazilian research community

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    Background: Aspect-Oriented Software Development (AOSD) is a paradigm that promotes advanced separation of concerns and modularity throughout the software development lifecycle, with a distinctive emphasis on modular structures that cut across traditional abstraction boundaries. In the last 15 years, research on AOSD has boosted around the world. The AOSD-BR research community (AOSD-BR stands for AOSD in Brazil) emerged in the last decade, and has provided different contributions in a variety of topics. However, despite some evidence in terms of the number and quality of its outcomes, there is no organized characterization of the AOSD-BR community that positions it against the international AOSD Research community and the Software Engineering Research community in Brazil. Aims: In this paper, our main goal is to characterize the AOSD-BR community with respect to the research developed in the last decade, confronting it with the AOSD international community and the Brazilian Software Engineering community. Method: Data collection, validation and analysis were performed in collaboration with several researchers of the AOSD-BR community. The characterization was presented from three different perspectives: (i) a historical timeline of events and main milestones achieved by the community; (ii) an overview of the research developed by the community, in terms of key challenges, open issues and related work; and (iii) an analysis on the impact of the AOSD-BR community outcomes in terms of well-known indicators, such as number of papers and number of citations. Results: Our analysis showed that the AOSD-BR community has impacted both the international AOSD Research community and the Software Engineering Research community in Brazil. (c) 2012 Elsevier Inc. All rights reserved.864905933National Institute of Science and Technology for Software Engineering (INES) [573964/2008-4, APQ-1037-1.03/08]National Institute of Science and Technology for Software Engineering (INES) [573964/2008-4, APQ-1037-1.03/08

    Genomic Epidemiology of 2015-2016 Zika Virus Outbreak in Cape Verde

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    During 2015-2016, Cape Verde, an island nation off the coast of West Africa, experienced a Zika virus (ZIKV) outbreak involving 7,580 suspected Zika cases and 18 microcephaly cases. Analysis of the complete genomes of 3 ZIKV isolates from the outbreak indicated the strain was of the Asian (not African) lineage. The Cape Verde ZIKV sequences formed a distinct monophylogenetic group and possessed 1-2 (T659A, I756V) unique amino acid changes in the envelope protein. Phylogeographic and serologic evidence support earlier introduction of this lineage into Cape Verde, possibly from northeast Brazil, between June 2014 and August 2015, suggesting cryptic circulation of the virus before the initial wave of cases were detected in October 2015. These findings underscore the utility of genomic-scale epidemiology for outbreak investigations.status: publishe

    Epilepsy in tuberous sclerosis complex: Findings from the TOSCA Study

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    To present the baseline data of the international TuberOus SClerosis registry to increase disease Awareness (TOSCA) with emphasis on the characteristics of epilepsies associated with tuberous sclerosis complex (TSC)
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