Mental Health and Safety in Schools: Children’s perceptions and experiences

The current study employed an exploratory analysis of children’s perceptions of safety, mental health and experiences with bullying in school. Secondary data from surveys administered to a Southwestern Ontario school board was used to gather frequency data in addition to exploring the associations between mental health, feelings of safety and experiences with bullying. Furthermore, a photovoice component was administered in a select school, intended to gain a deeper understanding of what leads children to feel safe and unsafe, while in school. Results highlight the number of children experiencing mental health concerns as well as the importance of support systems for children to feel safe and secure at school. The results are discussed in connection to previous findings that indicate the critical importance of exploring children’s experiences in school to aid in the promotion of safe, healthy school settings. Implications for schools and children’s mental health promotion and prevention efforts are discussed

Phonological variation and change in the regional French of Alsace: Supralocalisation, age, gender and the urban–rural dichotomy

This is the author accepted manuscript. The final version is available from Cambridge University Press via the DOI in this recordThis article examines patterns of variation and change in the phonology of the regional French of Alsace, within an overarching framework of regional dialect levelling (Kerswill, 2003) in the French of France. Data are drawn from an original corpus gathered in Strasbourg and a small village in a rural area of the Bas-Rhin. We analyse two well-known regional features in spontaneous speech: (h), the variable realisation of initial [h], and (ʒ), the non-assimilatory devoicing of /ʒ/. We focus on the effect on the variation observed of the major extra-linguistic variables of age, gender and social class as well as urban or rural community. While the results for class and location follow expected patterns, whereby working-class and rural speakers show higher rates of traditional non-standard variants, the principal observation is the decline and, in the case of (ʒ), apparent loss of such features. We thus provide new evidence in support of supralocalisation, not only in the urban context but also in the rural location. The results for gender are however less clearcut: there is an interaction with age, class and location, and disruption of the usual pattern of female-led adoption of supralocal norms.Arts and Humanities Research Council (AHRC

Progress in the molecular biology of inherited bleeding disorders

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73391/1/j.1365-2516.2008.01718.x.pd

Biological mechanisms underlying inter‐individual variation in factor VIII clearance in haemophilia

Previous studies have highlighted marked inter‐individual variations in factor VIII (FVIII) clearance between patients with haemophilia (PWH). The half‐life of infused FVIII has been reported to vary from as little as 5.3 hours in some adult PWH, up to as long as 28.8 hours in other individuals. These differences in clearance kinetics have been consistently observed using a number of different plasma‐derived and recombinant FVIII products. Furthermore, recent studies have demonstrated that half‐life for extended half‐life (EHL‐) FVIII products also demonstrates significant inter‐patient variation. Since time spent with FVIII trough levels <1% has been shown to be associated with increased bleeding risk in PWH on prophylaxis therapy, this variability in FVIII clearance clearly has major clinical significance. Recent studies have provided significant novel insights into the cellular basis underlying FVIII clearance pathways. In addition, accumulating data have shown that endogenous plasma VWF levels, ABO blood group and age, all play important roles in regulating FVIII half‐life in PWH. Indeed, multiple regression analysis suggests that together these factors account for approximately 34% of the total inter‐individual variation in FVIII clearance observed between subjects with severe haemophilia A. In this review, we consider these and other putative modulators of FVIII half‐life, and discuss the biological mechanisms through which these factors impact upon FVIII clearance in vivo.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/156160/2/hae14078.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/156160/1/hae14078_am.pd

International workshop on immune tolerance induction: consensus recommendations 1

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73382/1/j.1365-2516.2007.01497.x.pd

Recognizing the need for personalization of haemophilia patient‐reported outcomes in the prophylaxis era

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/134854/1/hae13066.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134854/2/hae13066_am.pd

Temperature mapping and thermal lensing in large-mode, high-power laser diodes

The authors use high-resolution charge-coupled device based thermoreflectance to derive two dimensional facet temperature maps of a λ = 1.55 μmλ=1.55μm InGaAsP/InPInGaAsP∕InP watt-class laser that has a large (>5×5 μm2)(>5×5μm2) fundamental optical mode. Recognizing that temperature rise in the laser will lead to refractive index increase, they use the measured temperature profiles as an input to a finite-element mode solver, predicting bias-dependent spatial mode behavior that agrees well with experimental observations. These results demonstrate the general usefulness of high-resolution thermal imaging for studying spatial mode dynamics in photonic devices.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87806/2/201110_1.pd

Naive Bayes novelty detection for a moving robot with whiskers

Novelty detection would be a useful ability for any autonomous robot that seeks to categorize a new environment or notice unexpected changes in its present one. A biomimetic robot (SCRATCHbot) inspired by the rat whisker system was here used to examine the performance of a novelty detection algorithm based on a 'naive' implementation of Bayes rule. Naive Bayes algorithms are known to be both efficient and effective, and also have links with proposed neural mechanisms for decision making. To examine novelty detection, the robot first used its whiskers to sense an empty floor, after which it was tested with a textured strip placed in its path. Given only its experience of the familiar situation, the robot was able to distinguish the novel event and localize it in time. Performance increased with the number of whiskers, indicating benefits from integrating over multiple streams of information. Considering the generality of the algorithm, we suggest that such novelty detection could have widespread applicability as a trigger to react to important features in the robot's environment. © 2010 IEEE

The DRIFT Dark Matter Experiments

The current status of the DRIFT (Directional Recoil Identification From Tracks) experiment at Boulby Mine is presented, including the latest limits on the WIMP spin-dependent cross-section from 1.5 kg days of running with a mixture of CS2 and CF4. Planned upgrades to DRIFT IId are detailed, along with ongoing work towards DRIFT III, which aims to be the world's first 10 m3-scale directional Dark Matter detector.Comment: Proceedings of the 3rd International conference on Directional Detection of Dark Matter (CYGNUS 2011), Aussois, France, 8-10 June 201