26 research outputs found
Sjögren's syndrome: State of the art on clinical practice guidelines
Sjögren's syndrome (SS) is a complex autoimmune rheumatic disease that specifically targets salivary and lachrymal glands. As such, patients typically had ocular and oral dryness and salivary gland swelling. Moreover, skin, nasal and vaginal dryness are frequently present. In addition to dryness, musculoskeletal pain and fatigue are the hallmarks of this disease and constitute the classic symptom triad presented by the vast majority of patients. Up to 30% to 50 % of patients with SS may present systemic disease; moreover, there is an increased risk for the development of non-Hodgkin's lymphoma that occurs in a minority of patients. The present work was developed in the framework of the European Reference Network (ERN) dedicated to Rare and Complex Connective Tissue and Musculoskeletal Diseases (ReCONNET). In line with its goals of aiming to improve early diagnosis, treatment and care of rare connective and musculoskeletal diseases, ERN-ReCONNET set to review the current state of clinical practice guidelines (CPGs) in the rare and complex connective tissue diseases of interest of the network. Therefore, the present work was aimed at providing a state of the art of CPGs for SS
ECMO for COVID-19 patients in Europe and Israel
Since March 15th, 2020, 177 centres from Europe and Israel have joined the study, routinely reporting on the ECMO support they provide to COVID-19 patients. The mean annual number of cases treated with ECMO in the participating centres before the pandemic (2019) was 55. The number of COVID-19 patients has increased rapidly each week reaching 1531 treated patients as of September 14th. The greatest number of cases has been reported from France (n = 385), UK (n = 193), Germany (n = 176), Spain (n = 166), and Italy (n = 136) .The mean age of treated patients was 52.6 years (range 16–80), 79% were male. The ECMO configuration used was VV in 91% of cases, VA in 5% and other in 4%. The mean PaO2 before ECMO implantation was 65 mmHg. The mean duration of ECMO support thus far has been 18 days and the mean ICU length of stay of these patients was 33 days. As of the 14th September, overall 841 patients have been weaned from ECMO
support, 601 died during ECMO support, 71 died after withdrawal of ECMO, 79 are still receiving ECMO support and for 10 patients status n.a. . Our preliminary data suggest that patients placed
on ECMO with severe refractory respiratory or cardiac failure secondary to COVID-19 have a reasonable (55%) chance of survival. Further extensive data analysis is expected to provide invaluable information on the demographics, severity of illness, indications and different ECMO management strategies in these patients
Einfaltige Antwort Auff die arg und listige Fragstück der Jesuiter an die Luthrischen Predigkanten, dardurch daß Jesuitisch schleichendt Gifft, unterm Schein grosser Witz außgegossen, dem Armen einfaltigen Mann entdeckt wirdt : Underscheiden in zwei Theil
The history of the persecutions of the protestants by the French Kings in the Principality of Orange, from the year 1660 to the year 1687
written by Monsieur Pineton ..
Jacobi Pinetons Von Chambrun Ihro Königlichen Hochheit Hoff-Predigers bey der Gemeine zu Oranien/ und Professoris in der Theologi Thränen/ In sich verfassende Die Verfolgungen/ so ergangen sind über das Gantze Fürstenthum Oranien Seither dem Jahr Sechszehen hundert sechtzig So wohl in Geist- als Weltlichen Sachen/ Wie auch Sehr merckwürdige und warhafftige Historien
The history of the persecutions of the Protestants by the French king in the principality of Orange from the year 1660 to the year 1687 with a particular account of the author's fall through the violence of the persecution / written by Monsieur Pineton.
A retrospective multicenter analysis on redo-laparoscopic anti-reflux surgery: conservative or conversion fundoplication?
A retrospective multicenter analysis on redo-laparoscopic anti-reflux surgery: conservative or conversion fundoplication?
International audienc