Primary Hyperparathyroidism Presenting with Multiple Pathological Fractures and Normocalcaemia

The diagnosis of primary hyperparathyroidism (PHPT) is a rarity in developing countries. We report a 30-year old Nigerian farmer seen at the Usmanu Danfodiyo University Teaching Hospital, Sokoto with multiple pathological fractures. The diagnosis of PHPT was made based on these bone changes and the elevated parathyroid hormone level. The patient however had normocalcaemia. Computerised tomography localised a left inferior parathyroid adenoma. He had uneventful parathyroidectomy but developed hungry bone syndrome that was successfully treated with active vitamin D and oral calcium. The differences in presentation between patients from developed countries as well as the apparent rarity of PHPT in tropical countries are stressed

Prevalence of Abnormal Cervical Smears from Sporadic Screening in a Gynaecological Clinic

The aim of the study was to find the prevalence of abnormal smears in an unscreened population of sexually active women attending a gynaecological clinic. “Pap” smears were taken sporadically for cytological examination from sexually active women attending gynaecological clinics at the Federal Medical Centre Gombe. Inflammation was the commonest abnormality in 52.5% (76/145) with human papilloma virus infection accounting for 22.1% of cases, while cervical intraepithelial neoplasia was seen in 17.9% (26/145) with CIN II and III accounting for 5.5%. There were statistically significant associations between previous conception, previous child birth and increasing number of deliveries with CIN. The Nigerian Medical Practitioner Vol. 51 (6) 2007: pp. 114-11

primary hyperpara thyroidism presenting with multiple paqthological fractures and normocal caemia

The diagnosis of primary hyperparathyroidism (PHPT) is a rarity in developing countries. We report a 30-year old Nigerian farmer seen at the Usmanu Danfodiyo University Teaching Hospital, Sokoto with multiple pathological fractures. The diagnosis of PHPT was made based on these bone changes and the elevated parathyroid hormone level. The patient however had normocalcaemia. Computerised tomography localised a left inferior parathyroid adenoma. He had uneventful parathyroidectomy but developed hungry bone syndrome that was successfully treated with active vitamin D and oral calcium. The differences in presentation between patients from developed countries as well as the apparent rarity of PHPT in tropical countries are stressed

Placental site trophoblastic tumour mimicking placenta previa

We present a 42-year-old Nigerian woman who had three previous caesarean sections and is being managed conservatively for placenta previa. She underwent a caesarean hysterectomy on account of uncontrollable bleeding, and histopathology revealed a placental site trophoblastic tumour

The epigastric heteropagus conjoined twins

Conjoined twins are rare and are classified as symmetrical or asymmetrical, in which a member, the host (autosite), is near normal and bears the parasite, which is incomplete, smaller, and fully dependent for growth on it. This form of conjoined twins is referred to as heteropagus and when attached to the epigastrium of the autosite is called epigastric heteropagus. Only 44 cases of epigastric heteropagus twins have been previously reported in the world literature. We hereby report the successful separation of a pair of heteropagus twins. (C) 2011 Elsevier Inc. All rights reserved

Endoscopic Findings And The Frequency Of Helicobacter Pylori Among Dyspeptic Patients In Maiduguri, North-Eastern Nigeria

Aim: To determine the types of upper gastrointestinal lesions and the frequency of Helicobacter pylori infection among dyspeptic patients in Maiduguri. Methods: Three hundred and thirty (330) dyspeptic patients undergoing endoscopy at the University of Maiduguri Teaching Hospital were prospectively studied. Gastric antral biopsy specimens obtained through endoscopic biopsy forceps were stained with haematoxylin and eosin. Modified Giemsa staining was employed to demonstrate the presence Helicobacter pylori. Results: One hundred and seventy one (51.8%) of the patients were males and 159 (48.2%) were females. Their ages ranged from 14 to 80 years with a mean of 38.7, the age group with highest frequency being 40 to 49 years. A total of 259 (78.5%) of the patients were positive for H. pylori. Two hundred and seventy one (82.1%) had endoscopically identifiable lesions. The most common lesion was oesophagitis which was seen in 67.0% of the patients followed by gastritis (60.0%) and duodenitis (27.9%). Gastric ulcer was recorded in 6.4 % of the patients while 4.8% and 1.7% had duodenal ulcer and gastric cancer respectively. The frequency of H. pylori among patients with gastritis was 89.1% while it was 83.3%, 100% and 61.9 % among patients with duodenitis, duodenal ulcer and gastric ulcer respectively, and 33.3% among those with gastric cancer. Conclusion: There is high frequency of H. pylori infection among dyspeptic patients in Maiduguri. The predominant endoscopic findings were oesophagitis, gastritis and duodenitis. Keywords: Helicobacter pylori, dyspepsia, endoscopy, frequencyHighland Medical Research Journal Vol. 5 (1) 2007 pp. 78-8