4 research outputs found

    A(40)Ar/(39) Ar study of oceanic and continental deformation processes during an oblique collision: Taconian orogeny in the Quebec reentrant of the Canadian Appalachians

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    International audienceTwo phases of penetrative deformation are documented in the Taconian hinterland of the Appalachian orogen in the Gaspé Peninsula. D1 is associated with the obduction of the Mont-Albert ophiolite onto the Paleozoic Laurentian margin, whereas D2 corresponds to later transport of allochthons across the margin. In the metamorphic sole, S1 is a SE-dipping mylonitic fabric with a downdip lineation. In underlying metabasalts, D1 is characterized by NW-overturned and recumbent folds, and a subhorizontal S1 schistosity with an ENE-trending orogen-parallel lineation. D2 is characterized by a S2 steeply dipping penetrative axial-planar crenulation cleavage and NE-trending F2 folds. The intraoceanic thrusting of ophiolite is dated at 465 Ma (early D1) whereas emplacement of ophiolite and subsequent deformation of the margin was recorded by isotopic signatures between 459 and 456 Ma (late D1). D2 is dated at 448 Ma throughout the hinterland. Taconian transpressive deformation is related to an oblique collision within the Quebec reentrant of the Canadian Appalachians during the Ordovician

    Knowledge Syntheses Search Strategy Repositories: Canadian Case Studies

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    Knowledge synthesis research is central to evidence-based medicine. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses literature search extension (PRISMA-S) outlines full reporting of the search strategy component including uploading documentation of all search strategies into a data repository to increase accessibility, transparency, and reproducibility. In response to the PRISMA-S recommendations, Canadian universities and health care institutions have been increasingly offering local services for librarians to support depositing and sharing search strategies in a digital data repository on the Borealis platform. Borealis, the Canadian Dataverse Repository, is a bilingual, multidisciplinary, secure, Canadian research data repository which supports open discovery, management, sharing, and preservation of Canadian research data. We argue that knowledge synthesis searches are data, and therefore, deserve a place in data repositories. Three case studies of knowledge synthesis repositories from three institutions will be presented: McGill University, Université de Montréal teaching hospitals, and the Health Sciences Information Consortium (HSIC) which includes the University of Toronto and affiliated hospitals. This talk will discuss the reasons for choosing a data repository, decisions made, challenges encountered, and lessons learned

    Characterizing Dysphonia After Pediatric Open Airway Reconstruction: Systematic Review and Meta-Analysis

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    <jats:sec><jats:title>Background</jats:title><jats:p> Pediatric laryngotracheal stenosis often requires open airway reconstruction. While these surgeries establish an airway for adequate ventilation, many patients develop subsequent dysphonia. Numerous studies have reported outcomes related to voice. </jats:p></jats:sec><jats:sec><jats:title>Objective</jats:title><jats:p> This study aims to evaluate dysphonia in pediatric patients following open airway reconstruction, focusing on acoustic parameters, perceptual voice quality, and voice-related quality of life. </jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p> A comprehensive search using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines across 6 databases identified articles involving pediatric patients who underwent open airway reconstruction and reported postoperative vocal acoustic parameters, perceptual voice quality, voice-related quality of life, or vocal mechanics. Articles were assessed for bias risk, and common outcomes were synthesized qualitatively and quantitatively using meta-analyses. </jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p> Among 4089 articles, 21 were included, involving 497 pediatric patients. Laryngotracheoplasty was the most common procedure followed by cricotracheal resection. The Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V) scale was frequently used to assess voice quality, with a mean score of 55.6 [95% confidence intervals (CIs): 47.9-63.3]. Voice-related quality of life was measured using the pediatric Voice Handicap Index (pVHI) and Pediatric Voice-Related Quality of Life Survey, with mean scores of 35.6 (95% CI: 21.4-49.7) and 83.7 (95% CI: 74.1-93.2), respectively. The fundamental frequency was 210.5 (95% CI: 174.6-246.3). Other common findings included supraglottic phonation, anterior commissure blunting, posterior glottic diastasis, and abnormal vocal cord mobility. </jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p> Pediatric patients experiencing dysphonia after open airway reconstruction exhibited moderately decreased voice quality and reduced voice-related quality of life. However, there was inconsistency in study protocols and outcome measures used. Preserving voice quality during airway reconstruction is crucial to avoid negative impacts on quality of life. </jats:p></jats:sec&gt
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