22 research outputs found

    Project Fog Drops - Investigation of warm fog properties and fog modification concepts Quarterly progress report

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    Ground and aerial applications of hygroscopic particles in fog dispersal experiment

    Investigation of warm fog properties and fog modification concepts

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    Coalescence of warm fog droplets with ionic surfactants, effects of monomolecular layers on droplet nuclei, and fog dynamics - mathematical mode

    Investigation of warm fog properties and fog modification concepts

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    Warm fog seeding to determine potential of various sized and unsized hygroscopic chemicals for fog dissipatio

    Characterizing Prostate Cancer Risk Through Multi-Ancestry Genome-Wide Discovery of 187 Novel Risk Variants

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    The transferability and clinical value of genetic risk scores (GRSs) across populations remain limited due to an imbalance in genetic studies across ancestrally diverse populations. Here we conducted a multi-ancestry genome-wide association study of 156,319 prostate cancer cases and 788,443 controls of European, African, Asian and Hispanic men, reflecting a 57% increase in the number of non-European cases over previous prostate cancer genome-wide association studies. We identified 187 novel risk variants for prostate cancer, increasing the total number of risk variants to 451. An externally replicated multi-ancestry GRS was associated with risk that ranged from 1.8 (per standard deviation) in African ancestry men to 2.2 in European ancestry men. The GRS was associated with a greater risk of aggressive versus non-aggressive disease in men of African ancestry (P = 0.03). Our study presents novel prostate cancer susceptibility loci and a GRS with effective risk stratification across ancestry groups
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