457 research outputs found

    People v. Holmes: And Sometimes it\u27s Not a Seizure

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    Applying Principles of Health Marketing to Private Practice Dietetics

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    The prevalence of chronic diseases in America is rising rapidly, requiring increased medical spending to manage these conditions. Treating chronic illnesses comprised seventy-eight percent of total health spending in 2003. In 2005, 133 million Americans were living with at least one chronic disease and this number is expected to increase to 157 million by 2020 (Wu & Green, 2000). The number of people with diabetes in the United States is projected to double in number from twenty-four million to forty-eight million in the next twenty-five years (Bodenheimer, Chen, & Bennett, 2009). There is a direct correlation between chronic disease and healthcare spending, with the average Medicare patient with one chronic condition seeing four physicians a year and patients with five or more chronic conditions seeing fourteen different physicians each year (Vogeli, et al., 2007). Medicare beneficiaries with five or more chronic diagnoses accounted for seventy-six percent of expenditures (Thorpe & Howard, 2006). As healthcare costs rise in the United States, more attention should be given to preventive medicine and lifestyle changes as treatment for chronic diseases and comorbidities. Programs such as the Centers for Disease Control and Prevention (CDC) Nutrition, Physical Activity, and Obesity Program; Planet Health; and Coordinated Approach to Child Health, which focus on healthy eating and increased physical activity, have the potential to prevent a significant number of children from becoming obese and therefore slowing the increase in diabetes (Cawley, 2007). Lifestyle is crucial for chronic disease prevention and proven to be effective, as evidenced by the Diabetes Prevention Study. This study provided diet and exercise plans, dietitian visits and physical training sessions and showed that lifestyle changes can prevent diabetes (Tuomilehto, et al., 2001). This is evidence that Registered Dietitians (RDs) play an important role in supporting healthy lifestyles and preventing and managing chronic disease. Private practice dietetics offers a unique role, as the RD is able to be more creative with services offered and approaches taken to prevent and manage chronic diseases. This paper discusses the application of principles of health marketing to private practice dietetics with the goal of increasing the reach of nutrition services into the community and the viability of a private practice.Master of Public Healt

    Syndecan-2 is a novel target of insulin-like growth factor binding protein-3 and is over-expressed in fibrosis

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    Extracellular matrix deposition and tissue scarring characterize the process of fibrosis. Transforming growth factor beta (TGFβ) and Insulin-like growth factor binding protein-3 (IGFBP-3) have been implicated in the pathogenesis of fibrosis in various tissues by inducing mesenchymal cell proliferation and extracellular matrix deposition. We identified Syndecan-2 (SDC2) as a gene induced by TGFβ in an IGFBP-3-dependent manner. TGFβ induction of SDC2 mRNA and protein required IGFBP-3. IGFBP-3 independently induced production of SDC2 in primary fibroblasts. Using an ex-vivo model of human skin in organ culture expressing IGFBP-3, we demonstrate that IGFBP-3 induces SDC2 ex vivo in human tissue. We also identified Mitogen-activated protein kinase-interacting kinase (Mknk2) as a gene induced by IGFBP-3. IGFBP-3 triggered Mknk2 phosphorylation resulting in its activation. Mknk2 independently induced SDC2 in human skin. Since IGFBP-3 is over-expressed in fibrotic tissues, we examined SDC2 levels in skin and lung tissues of patients with systemic sclerosis (SSc) and lung tissues of patients with idiopathic pulmonary fibrosis (IPF). SDC2 levels were increased in fibrotic dermal and lung tissues of patients with SSc and in lung tissues of patients with IPF. This is the first report describing elevated levels of SDC2 in fibrosis. Increased SDC2 expression is due, at least in part, to the activity of two pro-fibrotic factors, TGFβ and IGFBP-3. © 2012 Ruiz et al

    A physiologically-motivated compartment-based model of the effect of inhaled hypertonic saline on mucociliary clearance and liquid transport in cystic fibrosis

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    Background: Cystic Fibrosis (CF) lung disease is characterized by liquid hyperabsorption, airway surface dehydration, and impaired mucociliary clearance (MCC). Herein, we present a compartment-based mathematical model of the airway that extends the resolution of functional imaging data. Methods: Using functional imaging data to inform our model, we developed a system of mechanism-motivated ordinary differential equations to describe the mucociliary clearance and absorption of aerosolized radiolabeled particle and small molecules probes from human subjects with and without CF. We also utilized a novel imaging metric in vitro to gauge the fraction of airway epithelial cells that have functional ciliary activity. Results: This model, and its incorporated kinetic rate parameters, captures the MCC and liquid dynamics of the hyperabsorptive state in CF airways and the mitigation of that state by hypertonic saline treatment. Conclusions: We postulate, based on the model structure and its ability to capture clinical patient data, that patients with CF have regions of airway with diminished MCC function that can be recruited with hypertonic saline treatment. In so doing, this model structure not only makes a case for durable osmotic agents used in lung-region specific treatments, but also may provide a possible clinical endpoint, the fraction of functional ciliated airway

    Characteristics of body building standard style dancers on the example of pair of world champions

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    Aim of the studyThe aim of the study was to determine the specificity of somatic build ballroom dancers sporting standard style.MaterialsThe research material was sporting ballroom dancing couple having the highest international dance class "S". World Champions of 2013, the standard style. The length of the internship dance couples was 19 years. Subjects were trained from 6 to 7 days a week, after 3-4 hours a day. They were both 28 years.Methods Physical development assessment was based on anthropometric measurements of body weight and height, the length of the neck, upper and lower limbs, torso, thigh and lower leg, foot length, width, shoulders, pelvis, feet, chest, deep chest, circuits, waist, hips, thighs and ankles. Typological classification was also used to assess the specificity of physique subjects.ConclusionsA pair of dance sport sporty style with a high level of standard sports (with the 2013 World Champions.) characterized by a specific construction of somatic manifested a certain size characteristics and indicators of body (shown in this work).Presented by their size parameters of somatic and morphological indicators should be considered as a result of the impact of dance training and the requirements of the standard style of discipline and separately for dancers and dance together for a couple as the specifics of their selection

    Charakterystyka budowy ciała tancerzy stylu standardowego tańca sportowego na przykładzie pary mistrzów świata = Characteristics of body building standard style dancers on the example of pair of world champions

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    Pilewska Wiesława, Sech Patrycja, Pilewski Robert. Charakterystyka budowy ciała tancerzy stylu standardowego tańca sportowego na przykładzie pary mistrzów świata = Characteristics of body building standard style dancers on the example of pair of world champions. Journal of Education, Health and Sport. 2015;5(11):565-576. eISSN 2391-8306. DOIhttp://dx.doi.org/10.5281/zenodo.35698http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%2811%29%3A565-576http://pbn.nauka.gov.pl/works/684768Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011–2014http://journal.rsw.edu.pl/index.php/JHS/issue/archive Original Text published © The Author (s) 2015. Pilewska Wiesława, Sech Patrycja, Pilewski Robert. Charakterystyka budowy ciała tancerzy stylu standardowego tańca sportowego na przykładzie pary mistrzów świata. Quality in Sport. 2015;1(1):55-65. eISSN 2450-3118. The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015).755 Journal of Education, Health and Sport (null) 2391-8306 7© The Author (s) 2015;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland.Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 15.11.2015. Revised 20.11.2015. Accepted: 30.11.2015.  Wiesława Pilewska, Patrycja Sech, Robert PilewskiInstytut Kultury Fizycznej, Uniwersytet Kazimierza Wielkiego w Bydgoszczy Charakterystyka budowy ciała tancerzy stylu standardowegotańca sportowego na przykładzie pary mistrzów świataCharacteristics of body building standard style dancers on the example of pair of world champions   StreszczenieCel pracyCelem pracy było określenie specyfiki budowy somatycznej tancerzy sportowego tańca towarzyskiego stylu standardowego.Materiał Materiał badawczy stanowiła para sportowego tańca towarzyskiego posiadająca najwyższą, międzynarodową klasę taneczną „S”. Mistrzowie Świata z 2013 roku w stylu standardowym. Długość stażu tanecznego pary wynosiła 19 lat. Badane osoby trenowały od 6 do 7 dni w tygodniu, po 3-4 godziny dziennie. Oboje mieli po 28 lat.MetodaOceny rozwoju fizycznego dokonano na podstawie pomiarów antropometrycznych masy i wysokości ciała, długości szyi,  kończyn górnych i dolnych, tułowia, uda  i podudzia, długości stopy, szerokości barków, miednicy, stopy, klatki piersiowej, głębokości klatki piersiowej, obwodów talii, bioder, uda oraz podudzia. Na ich podstawie obliczono wskaźniki budowy ciała. Wykorzystano również klasyfikacje typologiczną dla oceny specyfiki budowy ciała badanych osób.WnioskiPara sportowego tańca sportowego stylu standardowego o wysokim poziomie sportowym (Mistrzowie Świata z 2013r.) charakteryzowała się specyficzną budową somatyczną przejawiającą się określoną wielkością cech i wskaźników budowy ciała. Prezentowane wielkości parametrów cech somatycznych i wskaźników morfologicznych należy traktować jako wynik wymagań stylu standardowego sportowego tańca, osobno dla tancerzy i tancerek a także wspólnie dla pary tanecznej jako specyfika ich doboru oraz wpływ treningu tanecznego na kształtowanie się ich somatotypu. Słowa kluczowe: taniec towarzyski, styl standardowy, budowa somatyczna, mistrzowie świata.       AbstractAim of the studyThe aim of the study was to determine the specificity of somatic build ballroom dancers sporting standard style.MaterialsThe research material was sporting ballroom dancing couple having the highest international dance class "S". World Champions of 2013, the standard style. The length of the internship dance couples was 19 years. Subjects were trained from 6 to 7 days a week, after 3-4 hours a day. They were both 28 years.Methods Physical development assessment was based on anthropometric measurements of body weight and height, the length of the neck, upper and lower limbs, torso, thigh and lower leg, foot length, width, shoulders, pelvis, feet, chest, deep chest, circuits, waist, hips, thighs and ankles. Typological classification was also used to assess the specificity of physique subjects.ConclusionsA pair of dance sport sporty style with a high level of standard sports (with the 2013 World Champions.) characterized by a specific construction of somatic manifested a certain size characteristics and indicators of body (shown in this work).Presented by their size parameters of somatic and morphological indicators should be considered as a result of the impact of dance training and the requirements of the standard style of discipline and separately for dancers and dance together for a couple as the specifics of their selection. Key words: ballroom dancing, standard style, construction somatic, World Champions
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