6,516 research outputs found
Trigger synchronisation circuits in CMS
We present the principles of the CMS method for synchronizing the trigger data at LHC. The method makes use of the LHC bunch gap and allows for re-synchronisation of the data every LHC orbit. It relies on the distribution by the TTC system of a signal synchronous with the first bunch in the orbit, and is implemented by dedicated synchronisation circuits in each trigger link. We report on the test of a prototype FPGA implementation
Adaptive Accelerated Molecular Dynamics (Ad-AMD) Revealing the Molecular Plasticity of P450cam
An extended accelerated molecular dynamics (AMD) methodology called adaptive AMD is presented. Adaptive AMD (Ad-AMD) is an efficient and robust conformational space sampling algorithm that is particularly-well suited to proteins with highly structured potential energy surfaces exhibiting complex, large-scale collective conformational transitions. Ad-AMD simulations of substrate-free P450cam reveal that this system exists in equilibrium between a fully and partially open conformational state. The mechanism for substrate binding depends on the size of the ligand. Larger ligands enter the P450cam binding pocket, and the resulting substrate-bound system is trapped in an open conformation via a population shift mechanism. Small ligands, which fully enter the binding pocket, cause an induced-fit mechanism, resulting in the formation of an energetically stable closed conformational state. These results are corroborated by recent experimental studies and potentially provide detailed insight into the functional dynamics and conformational behavior of the entire cytochrome-P450 superfamily
On the validity of mean-field amplitude equations for counterpropagating wavetrains
We rigorously establish the validity of the equations describing the
evolution of one-dimensional long wavelength modulations of counterpropagating
wavetrains for a hyperbolic model equation, namely the sine-Gordon equation. We
consider both periodic amplitude functions and localized wavepackets. For the
localized case, the wavetrains are completely decoupled at leading order, while
in the periodic case the amplitude equations take the form of mean-field
(nonlocal) Schr\"odinger equations rather than locally coupled partial
differential equations. The origin of this weakened coupling is traced to a
hidden translation symmetry in the linear problem, which is related to the
existence of a characteristic frame traveling at the group velocity of each
wavetrain. It is proved that solutions to the amplitude equations dominate the
dynamics of the governing equations on asymptotically long time scales. While
the details of the discussion are restricted to the class of model equations
having a leading cubic nonlinearity, the results strongly indicate that
mean-field evolution equations are generic for bimodal disturbances in
dispersive systems with \O(1) group velocity.Comment: 16 pages, uuencoded, tar-compressed Postscript fil
Reynolds number influences in aeronautics
Reynolds number, a measure of the ratio of inertia to viscous forces, is a fundamental similarity parameter for fluid flows and therefore, would be expected to have a major influence in aerodynamics and aeronautics. Reynolds number influences are generally large, but monatomic, for attached laminar (continuum) flow; however, laminar flows are easily separated, inducing even stronger, non-monatomic, Reynolds number sensitivities. Probably the strongest Reynolds number influences occur in connection with transitional flow behavior. Transition can take place over a tremendous Reynolds number range, from the order of 20 x 10(exp 3) for 2-D free shear layers up to the order of 100 x 10(exp 6) for hypersonic boundary layers. This variability in transition behavior is especially important for complex configurations where various vehicle and flow field elements can undergo transition at various Reynolds numbers, causing often surprising changes in aerodynamics characteristics over wide ranges in Reynolds number. This is further compounded by the vast parameterization associated with transition, in that any parameter which influences mean viscous flow development (e.g., pressure gradient, flow curvature, wall temperature, Mach number, sweep, roughness, flow chemistry, shock interactions, etc.), and incident disturbance fields (acoustics, vorticity, particulates, temperature spottiness, even electro static discharges) can alter transition locations to first order. The usual method of dealing with the transition problem is to trip the flow in the generally lower Reynolds number wind tunnel to simulate the flight turbulent behavior. However, this is not wholly satisfactory as it results in incorrectly scaled viscous region thicknesses and cannot be utilized at all for applications such as turbine blades and helicopter rotors, nacelles, leading edge and nose regions, and High Altitude Long Endurance and hypersonic airbreathers where the transitional flow is an innately critical portion of the problem
Anticipating Stream Ecosystem Responses to Climate Change: Toward Predictions That Incorporate Effects via Land–Water Linkages
Climate change (CC) is projected to increase the frequency and severity of natural disturbances (wildfires, insect outbreaks, and debris flows) and shift distributions of terrestrial ecosystems on a global basis. Although such terrestrial changes may affect stream ecosystems, they have not been incorporated into predictions of stream responses to CC. Here, we introduce a conceptual framework to evaluate to what extent responses of streams to CC will be driven by not only changes in thermal and hydrologic regimes, but also alterations of terrestrial processes. We focused on forested water-sheds of western North America because this region is projected to experience CC-induced alteration of terrestrial processes. This provided a backdrop for investigating interactive effects of climate and terrestrial responses on streams. Because stream responses to terrestrial processes have been well-studied in contexts largely independent of CC research, we synthesized this knowledge to demonstrate how CC-induced alterations of terrestrial ecosystems may affect streams. Our synthesis indicated that altered terrestrial processes will change terrestrial–aquatic linkages and autotrophic production, potentially yielding greater sensitivity of streams to CC than would be expected based on shifts in temperature and precipitation regime alone. Despite uncertainties that currently constrain predictions regarding stream responses to these additional pathways of change, this synthesis highlighted broader effects of CC that require additional research. Based on widespread evidence that CC is linked to changing terrestrial processes, we conclude that accurate predictions of CC effects on streams may be coupled to the accuracy of predictions for long-term changes in terrestrial ecosystems
Quantum Films Adsorbed on Graphite: Third and Fourth Helium Layers
Using a path-integral Monte Carlo method for simulating superfluid quantum
films, we investigate helium layers adsorbed on a substrate consisting of
graphite plus two solid helium layers. Our results for the promotion densities
and the dependence of the superfluid density on coverage are in agreement with
experiment. We can also explain certain features of the measured heat capacity
as a function of temperature and coverage.Comment: 13 pages in the Phys. Rev. two-column format, 16 Figure
Disorder-induced magnetic memory: Experiments and theories
Beautiful theories of magnetic hysteresis based on random microscopic
disorder have been developed over the past ten years. Our goal was to directly
compare these theories with precise experiments. We first developed and then
applied coherent x-ray speckle metrology to a series of thin multilayer
perpendicular magnetic materials. To directly observe the effects of disorder,
we deliberately introduced increasing degrees of disorder into our films. We
used coherent x-rays to generate highly speckled magnetic scattering patterns.
The apparently random arrangement of the speckles is due to the exact
configuration of the magnetic domains in the sample. In effect, each speckle
pattern acts as a unique fingerprint for the magnetic domain configuration.
Small changes in the domain structure change the speckles, and comparison of
the different speckle patterns provides a quantitative determination of how
much the domain structure has changed. How is the magnetic domain configuration
at one point on the major hysteresis loop related to the configurations at the
same point on the loop during subsequent cycles? The microscopic return-point
memory(RPM) is partial and imperfect in the disordered samples, and completely
absent when the disorder was not present. We found the complementary-point
memory(CPM) is also partial and imperfect in the disordered samples and
completely absent when the disorder was not present. We found that the RPM is
always a little larger than the CPM. We also studied the correlations between
the domains within a single ascending or descending loop. We developed new
theoretical models that do fit our experiments.Comment: 26 pages, 25 figures, Accepted by Physical Review B 01/25/0
Top Quarks and Electroweak Symmetry Breaking in Little Higgs Models
`Little Higgs' models, in which the Higgs particle arises as a
pseudo-Goldstone boson, have a natural mechanism of electroweak symmetry
breaking associated with the large value of the top quark Yukawa coupling. The
mechanism typically involves a new heavy SU(2)_{L} singlet top quark, T. We
discuss the relationship of the Higgs boson and the two top quarks. We suggest
experimental tests of the Little Higgs mechanism of electroweak symmetry
breaking using the production and decay of the T at the Large Hadron Collider.Comment: 28 pages, 6 figures; new ST fits (Fig. 3,4
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