729 research outputs found

    Advice from the Webmaster: Be Paranoid

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    In the 17+ years I’ve been webmaster at Linfield College, I have learned the internet can hurt you anonymously, quickly and painfully. There isn’t enough space in this magazine to cover the topic in detail. But if I had to give an elevator pitch about what you should worry about and what you should do based on my experiences and what Linfield’s Information Technology support desk deals with, it would be this

    Seeing through Sound

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    Linfield College webmaster Jonathan Pierce explains the opportunity he had to learn what Linfield\u27s website looks like to someone who can\u27t see

    Leaders\u27 Strategies to Support and Accommodate Employees with High-Functioning Autism

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    Leaders often lack strategies to create supportive and accommodating workplaces that capitalize on the unique skillset of autistic employees. Research has shown that employers benefit from creating supports; however, there is a lack of research on how or why organization leaders provide support and accommodations. The purpose of this descriptive case study was to identify leaders\u27 strategies for supporting autistic employees. The research question centered on managements\u27 support and accommodations for employees while capitalizing on their strengths. The conceptual framework included labor process to address management extracting benefits from labor, and resource-based theory to examine gaining a competitive advantage by using rare resources. Purposive sampling was used to select 11 leaders, managers, or frontline supervisors for in-person semistructured interviews from a northern Illinois organization that recruits and hires employees with autism. Other data sources for triangulation included communications, manuals, observations, photos, artifacts, and field notes following Yin\u27s 5-step analytic model. Eight themes emerged: (a) advocating for self and others; (b) mission, vision, values, and social responsibility; (c) autism challenges; (d) nonphysical support; (e) physical accommodations; (f) policies, procedures, and funding; (g) support personnel; and (h) unique skillset. The results encompass a mission-driven approach to support and accommodation. This study contributes to social change by demonstrating how managers can use disabled employees and assist them in becoming productive members in the workplace and society, while gaining a feeling of self-worth, dignity, and independence. This reduces the burden on taxpayers for care

    On a discrete version of Tanaka's theorem for maximal functions

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    In this paper we prove a discrete version of Tanaka's Theorem \cite{Ta} for the Hardy-Littlewood maximal operator in dimension n=1n=1, both in the non-centered and centered cases. For the discrete non-centered maximal operator M~\widetilde{M} we prove that, given a function f:Z→Rf: \mathbb{Z} \to \mathbb{R} of bounded variation, Var(M~f)≤Var(f),\textrm{Var}(\widetilde{M} f) \leq \textrm{Var}(f), where Var(f)\textrm{Var}(f) represents the total variation of ff. For the discrete centered maximal operator MM we prove that, given a function f:Z→Rf: \mathbb{Z} \to \mathbb{R} such that f∈ℓ1(Z)f \in \ell^1(\mathbb{Z}), Var(Mf)≤C∥f∥ℓ1(Z).\textrm{Var}(Mf) \leq C \|f\|_{\ell^1(\mathbb{Z})}. This provides a positive solution to a question of Haj{\l}asz and Onninen \cite{HO} in the discrete one-dimensional case.Comment: V4 - Proof of Lemma 3 update

    WRIT 201.08: College Writing II

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    WRIT 101.12: College Writing I

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    A qualitative mapping and evaluation of an aerospace supply chain strategy

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    Thesis (M. Eng. in Logistics)--Massachusetts Institute of Technology, Engineering Systems Division, 2011.Cataloged from PDF version of thesis.Includes bibliographical references (p. 55-56).An effective supply chain is critical to the success of the products and services sold by companies. Companies must have an explicit understanding of what the supply chain strategy is in order to evaluate it. While most organizations have well-documented business strategies, they lack the same for their supply chain strategy. The methodology proposed by Perez-Franco, Singh, and Sheffi (201 1a; 201 1b) is a way to evaluate a supply chain strategy by using interviews, surveys, and discussions. The goal for this project was to test the applicability of the Perez-Franco et al. methodology to the aerospace industry through an applied case. We conducted a qualitative mapping of the supply chain strategy for a specific satellite program in Lockheed Martin Space Systems (LMSS). This thesis research is the first time the methodology has been applied and tested with a company in the aerospace industry. As a whole, LMSS has increased focus on their supply chain, and works to directly align their supply chain with their business objectives. For our case, we selected a specific project within the Space Systems division that lacks an explicitly stated supply chain strategy and has a potential gap with objectives. Through our research, we found that the Perez-Franco et al. methodology is applicable to the aerospace industry. As a result of this case application, we propose and present potential deviations and additions to build upon the methodology that yields interesting insights. The results with LMSS revealed areas of disagreement identified through evaluating themes of support, consistency, and sufficiency. Additionally, the methodology allowed us to conduct a diagnostic of the supply chain strategy against business goals. The primary conclusion in the diagnostic was a perceived conflict between quality and affordability initiatives. This is the key recommendation that the company should investigate further to locate the root cause(s) of the disagreement. Outcomes from this case show that the methodology can be applied to a wide number of industries.by Jonathan Hung and Nicholas Pierce.M.Eng.in Logistic

    Exquisite Sequence Selectivity with Small Conditional RNAs

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    Dynamic RNA nanotechnology based on programmable hybridization cascades with small conditional RNAs (scRNAs) offers a promising conceptual framework for engineering programmable conditional regulation in vivo. While single-base substitution (SBS) somatic mutations and single-nucleotide polymorphisms (SNPs) are important markers and drivers of disease, it is unclear whether synthetic RNA signal transducers are sufficiently programmable to accept a cognate RNA input while rejecting single-nucleotide sequence variants. Here, we explore the limits of scRNA programmability, demonstrating isothermal, enzyme-free genotyping of RNA SBS cancer markers and SNPs using scRNAs that execute a conditional hybridization cascade in the presence of a cognate RNA target. Kinetic discrimination can be engineered on a time scale of choice from minutes to days. To discriminate even the most challenging single-nucleotide sequence variants, including those that lead to nearly isoenergetic RNA wobble pairs, competitive inhibition with an unstructured scavenger strand or with other scRNAs provides a simple and effective principle for achieving exquisite sequence selectivity
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