Educational profession-oriented propaedeutic Russian language course as a basis of coming of international students of pre-university training stage into the educational medium of the higher medical institution

Цель статьи - рассмотреть некоторые способы и методы (фреймовый подход) формирования лингвокультурологической медицинской компетенции иностранных учащихся предвузовского этапа на занятиях по русскому языку общелитературного стиля в соответствии со спецификой их будущего обучения в русскоязычной среде медицинского вуза. Актуальность исследования заключается в том, что учебный пропедевтический курс русского языка, ориентированный на изучение иностранными учащимися языка медицинской науки, является важнейшим и необходимым условием для их обучения в медицинском университете. Преподавание основывается на использовании общедидактических и методических принципов начального обучения русскому языку будущих студентов- медиков, которые способствуют дальнейшему усвоению и совершенствованию учебно- профессиональных знаний в условиях русской языковой среды медицинского вуза. В процессе исследования были использованы следующие методы: теоретический и практический анализ научной литературы по методике преподавания иностранного языка и русского как иностранного, аудиовизуальное наблюдение, беседы с иностранными студентами, пробное обучение. Результаты. В процессе изучения русского языка иностранные учащиеся приобретают новые знания, расширяется их эрудиция, кругозор. Иностранные учащиеся предвузовского этапа входят в мир языка медицинской науки, знакомясь с элементами её лингвистической, коммуникативной и культурологической базы. Выводы: пропедевтический курс русского языка закладывает основы знаний о специфике изучения медицины на русском языке, которые помогут иностранным учащимся предвузовского этапа подготовки спустя год войти в образовательную среду медицинского университета.The aim of the research is to consider some ways and methods (frame approach) of forming lingual- cultural medical competence of international students of pre-University training stage at the Russian Language classes in accordance with the specifics of their future learning in Russian-speaking medium of higher medical institution. Relevance of the study lies in the fact that educational propaedeutic course of the Russian Language, focused on training foreign students the language of medical science, is the most important and necessary condition for their studying in the medical university. Training is based on the usage of general didactic and methodical principles of elementary level of teaching Russian the future medical students, which promoting further learning and mastering the educational-professional knowledge in the conditions of Russian speaking environment of higher medical institution. The author has used the following methods: theoretical and practical analysis of scientific literature on methods of teaching foreign language and Russian as a foreign language, audio-visual monitoring, interviews with foreign students, experimental teaching. Results. When learning Russian the international students get knowledge, enlarge their erudition, the outlook. International students of pre-University training stage come into the world of the Language of medical science, becoming acquainted with the elements of its linguistic, communicative and cultural base. Conclusion. The propaedeutic course of Russian lays foundations of knowledge of specifics of learning medicine in Russian, which will help international students of pre-university training stage to be admitted to the educational environment of medical University after the first year of studying

Исследование реологических свойств растворов ксантановой смолы и крахмала для оценки межмолекулярного взаимодействия данных реагентов в биополимерных буровых растворах

Работа направленна на разработку систем биополимерных растворов для бурения горизонтальных участков скважин с повышенной эффективностью очистки ствола.The work is aimed to develope systems of biopolymer drilling fluids for horizontal drilling with increased efficiency of wellbore cleaning

Lack of influence of the COX inhibitors metamizol and diclofenac on platelet GPIIb/IIIa and P-selectin expression in vitro

BACKGROUND: The effect of non-steroidal anti-inflammatory drugs (NSAIDs) for reduced platelet aggregation and thromboxane A(2 )synthesis has been well documented. However, the influence on platelet function is not fully explained. Aim of this study was to examine the influence of the COX-1 inhibiting NSAIDs, diclofenac and metamizol on platelet activation and leukocyte-platelet complexes, in vitro. Surface expression of GPIIb/IIIa and P-selectin on platelets, and the percentage of platelet-leukocyte complexes were investigated. METHODS: Whole blood was incubated with three different concentrations of diclofenac and metamizol for 5 and 30 minutes, followed by activation with TRAP-6 and ADP. Rates of GPIIb/IIIa and P-selectin expression, and the percentage of platelet-leukocyte complexes were analyzed by a flow-cytometric assay. RESULTS: There were no significant differences in the expression of GPIIb/IIIa and P-selectin, and in the formation of platelet-leukocyte complexes after activation with ADP and TRAP-6, regarding both the time of incubation and the concentrations of diclofenac and metamizol. CONCLUSIONS: Accordingly, the inhibitory effect of diclofenac and metamizol on platelet aggregation is not related to a reduced surface expression of P-selectin and GPIIb/IIIa on platelets

Prognostic factors in 264 adults with invasive Scedosporium spp. and Lomentospora prolificans infection reported in the literature and FungiScope

Invasive Scedosporium spp. and Lomentospora prolificans infections are an emerging threat in immunocompromised and occasionally in healthy hosts. Scedosporium spp. is intrinsically resistant to most, L. prolificans to all the antifungal drugs currently approved, raising concerns about appropriate treatment decisions. High mortality rates of up to 90% underline the need for comprehensive diagnostic workup and even more for new, effective antifungal drugs to improve patient outcome. For a comprehensive analysis, we identified cases of severe Scedosporium spp. and L. prolificans infections from the literature diagnosed in 2000 or later and the FungiScopeVR registry. For 208 Scedosporium spp. infections solid organ transplantation (n¼58, 27.9%) and for 56 L. prolificans infection underlying malignancy (n¼28, 50.0%) were the most prevalent risk factors. L. prolificans infections frequently presented as fungemia (n¼26, 46.4% versus n¼12, 5.8% for Scedosporium spp.). Malignancy, fungemia, CNS and lung involvement predicted worse outcome for scedosporiosis and lomentosporiosis. Patients treated with voriconazole had a better overall outcome in both groups compared to treatment with amphotericin B formulations. This review discusses the epidemiology, prognostic factors, pathogen susceptibility to approved and investigational antifungals, and treatment strategies of severe infections caused by Scedosporium spp. and L. prolificans