18 research outputs found
Notes of Contributors, Notes on Editorial Advisors
Notes of Contributors, Notes on Editorial Advisor
Respiratory effects of different recruitment maneuvers in acute respiratory distress syndrome
Constraints on the structure and seasonal variations of Triton's atmosphere from the 5 October 2017 stellar occultation and previous observations
Context. A stellar occultation by Neptune's main satellite, Triton, was observed on 5 October 2017 from Europe, North Africa, and the USA. We derived 90 light curves from this event, 42 of which yielded a central flash detection.
Aims. We aimed at constraining Triton's atmospheric structure and the seasonal variations of its atmospheric pressure since the Voyager 2 epoch (1989). We also derived the shape of the lower atmosphere from central flash analysis.
Methods. We used Abel inversions and direct ray-tracing code to provide the density, pressure, and temperature profiles in the altitude range similar to 8 km to similar to 190 km, corresponding to pressure levels from 9 mu bar down to a few nanobars.
Results. (i) A pressure of 1.18 +/- 0.03 mu bar is found at a reference radius of 1400 km (47 km altitude). (ii) A new analysis of the Voyager 2 radio science occultation shows that this is consistent with an extrapolation of pressure down to the surface pressure obtained in 1989. (iii) A survey of occultations obtained between 1989 and 2017 suggests that an enhancement in surface pressure as reported during the 1990s might be real, but debatable, due to very few high S/N light curves and data accessible for reanalysis. The volatile transport model analysed supports a moderate increase in surface pressure, with a maximum value around 2005-2015 no higher than 23 mu bar. The pressures observed in 1995-1997 and 2017 appear mutually inconsistent with the volatile transport model presented here. (iv) The central flash structure does not show evidence of an atmospheric distortion. We find an upper limit of 0.0011 for the apparent oblateness of the atmosphere near the 8 km altitude.J.M.O. acknowledges financial support from the Portuguese Foundation for Science and Technology (FCT) and the European Social Fund (ESF) through the PhD grant SFRH/BD/131700/2017. The work leading to these results has received funding from the European Research Council under the European Community's H2020 2014-2021 ERC grant Agreement nffi 669416 "Lucky Star". We thank S. Para who supported some travels to observe the 5 October 2017 occultation. T.B. was supported for this research by an appointment to the National Aeronautics and Space Administration (NASA) Post-Doctoral Program at the Ames Research Center administered by Universities Space Research Association (USRA) through a contract with NASA. We acknowledge useful exchanges with Mark Gurwell on the ALMA CO observations. This work has made use of data from the European Space Agency (ESA) mission Gaia (https://www.cosmos.esa.int/gaia), processed by the Gaia Data Processing and Analysis Consortium (DPAC, https://www.cosmos.esa.int/web/gaia/dpac/consortium).Funding for the DPAC has been provided by national institutions, in particular the institutions participating in the Gaia Multilateral Agreement. J.L.O., P.S.-S., N.M. and R.D. acknowledge financial support from the State Agency for Research of the Spanish MCIU through the "Center of Excellence Severo Ochoa" award to the Instituto de Astrofisica de Andalucia (SEV-2017-0709), they also acknowledge the financial support by the Spanish grant AYA-2017-84637-R and the Proyecto de Excelencia de la Junta de Andalucia J.A. 2012-FQM1776. The research leading to these results has received funding from the European Union's Horizon 2020 Research and Innovation Programme, under Grant Agreement no. 687378, as part of the project "Small Bodies Near and Far" (SBNAF). P.S.-S. acknowledges financial support by the Spanish grant AYA-RTI2018-098657-J-I00 "LEO-SBNAF". The work was partially based on observations made at the Laboratorio Nacional de Astrofisica (LNA), Itajuba-MG, Brazil. The following authors acknowledge the respective CNPq grants: F.B.-R. 309578/2017-5; R.V.-M. 304544/2017-5, 401903/2016-8; J.I.B.C. 308150/2016-3 and 305917/2019-6; M.A. 427700/20183, 310683/2017-3, 473002/2013-2. This study was financed in part by the Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior -Brasil (CAPES) -Finance Code 001 and the National Institute of Science and Technology of the e-Universe project (INCT do e-Universo, CNPq grant 465376/2014-2). G.B.R. acknowledges CAPES-FAPERJ/PAPDRJ grant E26/203.173/2016 and CAPES-PRINT/UNESP grant 88887.571156/2020-00, M.A. FAPERJ grant E26/111.488/2013 and A.R.G.Jr. FAPESP grant 2018/11239-8. B.E.M. thanks CNPq 150612/2020-6 and CAPES/Cofecub-394/2016-05 grants. Part of the photometric data used in this study were collected in the frame of the photometric observations with the robotic and remotely controlled telescope at the University of Athens Observatory (UOAO; Gazeas 2016). The 2.3 m Aristarchos telescope is operated on Helmos Observatory by the Institute for Astronomy, Astrophysics, Space Applications and Remote Sensing of the National Observatory of Athens. Observations with the 2.3 m Aristarchos telescope were carried out under OPTICON programme. This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 730890. This material reflects only the authors views and the Commission is not liable for any use that may be made of the information contained therein. The 1.
2m Kryoneri telescope is operated by the Institute for Astronomy, Astrophysics, Space Applications and Remote Sensing of the National Observatory of Athens. The Astronomical Observatory of the Autonomous Region of the Aosta Valley (OAVdA) is managed by the Fondazione Clement Fillietroz-ONLUS, which is supported by the Regional Government of the Aosta Valley, the Town Municipality of Nus and the "Unite des Communes valdotaines Mont-Emilius". The 0.81 m Main Telescope at the OAVdA was upgraded thanks to a Shoemaker NEO Grant 2013 from The Planetary Society. D.C. and J.M.C. acknowledge funds from a 2017 'Research and Education' grant from Fondazione CRT-Cassa di Risparmio di Torino. P.M. acknowledges support from the Portuguese Fundacao para a Ciencia e a Tecnologia ref. PTDC/FISAST/29942/2017 through national funds and by FEDER through COMPETE 2020 (ref. POCI010145 FEDER007672). F.J. acknowledges Jean Luc Plouvier for his help. S.J.F. and C.A. would like to thank the UCL student support observers: Helen Dai, Elise Darragh-Ford, Ross Dobson, Max Hipperson, Edward Kerr-Dineen, Isaac Langley, Emese Meder, Roman Gerasimov, Javier Sanjuan, and Manasvee Saraf. We are grateful to the CAHA, OSN and La Hita Observatory staffs. This research is partially based on observations collected at Centro Astronomico HispanoAleman (CAHA) at Calar Alto, operated jointly by Junta de Andalucia and Consejo Superior de Investigaciones Cientificas (IAA-CSIC). This research was also partially based on observation carried out at the Observatorio de Sierra Nevada (OSN) operated by Instituto de Astrofisica de Andalucia (CSIC). This article is also based on observations made with the Liverpool Telescope operated on the island of La Palma by Liverpool John Moores University in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofisica de Canarias with financial support from the UK Science and Technology Facilities Council. Partially based on observations made with the Tx40 and Excalibur telescopes at the Observatorio Astrofisico de Javalambre in Teruel, a Spanish Infraestructura Cientifico-Tecnica Singular (ICTS) owned, managed and operated by the Centro de Estudios de Fisica del Cosmos de Aragon (CEFCA). Tx40 and Excalibur are funded with the Fondos de Inversiones de Teruel (FITE). A.R.R. would like to thank Gustavo Roman for the mechanical adaptation of the camera to the telescope to allow for the observation to be recorded. R.H., J.F.R., S.P.H. and A.S.L. have been supported by the Spanish projects AYA2015-65041P and PID2019-109467GB-100 (MINECO/FEDER, UE) and Grupos Gobierno Vasco IT1366-19. Our great thanks to Omar Hila and their collaborators in Atlas Golf Marrakech Observatory for providing access to the T60cm telescope. TRAPPIST is a project funded by the Belgian Fonds (National) de la Recherche Scientifique (F.R.S.-FNRS) under grant PDR T.0120.21. TRAPPIST-North is a project funded by the University of Liege, and performed in collaboration with Cadi Ayyad University of Marrakesh. E.J. is a FNRS Senior Research Associate
Approches thérapeutiques des agénésies
MONTPELLIER-BU MĂ©decine UPM (341722108) / SudocMONTPELLIER-BU Odontologie (341722110) / SudocPARIS-BIUM (751062103) / SudocMONTPELLIER-BU MĂ©decine (341722104) / SudocSudocFranceF
Lâentreprise comme communautĂ©Â ?
Les excĂšs du capitalisme industriel et financier et les difficultĂ©s Ă©conomiques ont dynamisĂ© la rĂ©flexion acadĂ©mique sur le concept de responsabilitĂ© sociale des entreprises (RSE), comme ils conduisaient depuis plus dâun siĂšcle Ă un approfondissement de la doctrine sociale de lâĂglise. Dans lâhistoire Ă©conomique contemporaine, la RSE prend le relais du paternalisme au sein dâun environnement Ă©conomique marquĂ© dĂ©sormais par la technique et son corollaire, lâinnovation, avec un environnement social construit autour dâune plus grande autonomie des personnes que par le passĂ©. Questionnant les formes les plus financiĂšres du capitalisme, la RSE propose des rĂ©ponses sans pour autant construire, pas plus que ne le faisait le paternalisme, la base incontestable dâune communautĂ© solidaire dans le quotidien de la vie des personnes qui concourent Ă lâactivitĂ© de lâentreprise. Il reste que les piliers Ă©conomiques, sociaux et environnementaux de la RSE constituent des soutiens Ă la rĂ©flexion et Ă lâaction pour des entrepreneurs et leurs Ă©quipes qui donnent Ă leur activitĂ© managĂ©riale le sens dâune vĂ©ritable crĂ©ation humaine. Lâexemple concret dâune sociĂ©tĂ© de cosmĂ©tiques illustre dans lâarticle les synergies existant entre les luttes contre lâobsolescence Ă©conomique et contre lâobsolescence morale.The excesses of industrial and financial capitalism and its economic difficulties have fuelled academic discussions on the concept of the social responsibility of enterprises (SRE), just as they have led to a deepening of the social doctrine of the Church for more than a century. In modern economic history, the SRE has come to succeed paternalism, the unquestionable basis of a supportive community in the day-to-day of the life of people who contribute to the enterpriseâs activity. The economic, social and environmental pillars of the SRE, however, foster the reflection and the action of entrepreneurs and their teams, giving the managerial activity the sense of a real human creation. The concrete case of a cosmetics company will serve to illustrate the synergy existing between the struggles against economic obsolescence and against moral obsolescence
Lisibilité
Depuis prĂšs de 30 ans, les sciences humaines et sociales se sont employĂ©es, en Allemagne comme en France, Ă Ă©largir le concept de « lisibilitĂ© » au-delĂ de la rĂ©fĂ©rence au texte Ă©crit. Ce numĂ©ro de Trivium rassemble quelques-unes des voix majeures dans ce dĂ©bat. Ce faisant, il rend compte de la formation d'un mode de lecture qui, entre microhistoire, sĂ©miologie, psychanalyse, histoire culturelle, physionomie et mantique, cherche sa mĂ©thodologie et renoue avec un lire archaĂŻque auquel aucune alphabĂ©tisation ne prĂ©pare. Comme si la lecture de la trace (et plus largement : d'indices, de symptĂŽmes, de prĂ©sages, etc.) redevenait, Ă la modernitĂ©, une technique culturelle, Ă©lĂ©mentaire et inaugurale d'interprĂ©tation, qui nous met Ă nouveau face Ă la question de la lisibilitĂ© du monde. Ce numĂ©ro a Ă©tĂ© rĂ©alisĂ© avec le soutien de l'Agence Nationale de la Recherche (ANR), de la Deutsche Forschungsgemeinschaft (DFG) ainsi que de la DGLFLF. Seit ĂŒber 30 Jahren gibt es in den deutschen wie französischen Kultur- und Geisteswissenschaften das Bestreben, den Begriff der »Lesbarkeit« von seiner engen Bindung an den geschriebenen Text zu emanzipieren. Die vorliegende Ausgabe von Trivium lĂ€sst einige der maĂgeblichen Stimmen in dieser Debatte zu Wort kommen. Auf der gemeinsamen SchnittflĂ€che von Mikrohistorie, Semiologie, Psychoanalyse, Kulturgeschichte, Physiognomie und Mantik zeichnet sich ein neues und zugleich altes VerstĂ€ndnis des Lesens ab. Wenn sich in der Moderne die Frage nach dem Lesen von Spuren â und damit im weiteren Sinne von Indizien, Symptomen, Vorzeichen etc. â neu stellt, so wird damit an eine archaische Praxis des Lesens neu angeknĂŒpft, welche uns vor das unabschlieĂbare Problem der Lesbarkeit der Welt stellt. Diese Ausgabe wurde publiziert mit UnterstĂŒtzung der Deutschen Forschungsgemeinschaft (DFG), der Agence Nationale de la Recherche (ANR) sowie des franzözischen Ministeriums fĂŒr Kultur (DGLFLF)
Endothelial autophagic flux hampers atherosclerotic lesion development
International audienceBlood flowing in arteries generates shear forces at the surface of the vascular endothelium that control its anti-atherogenic properties. However, due to the architecture of the vascular tree, these shear forces are heterogeneous and atherosclerotic plaques develop preferentially in areas where shear is low or disturbed. Here we review our recent study showing that elevated shear forces stimulate endothelial autophagic flux and that inactivating the endothelial macroautophagy/autophagy pathway promotes a proinflammatory, prosenescent and proapoptotic cell phenotype despite the presence of atheroprotective shear forces. Specific deficiency in endothelial autophagy in a murine model of atherosclerosis stimulates the development of atherosclerotic lesions exclusively in areas of the vasculature that are normally resistant to atherosclerosis. Our findings demonstrate that adequate endothelial autophagic flux limits atherosclerotic plaque formation by preventing endothelial apoptosis, senescence and inflammation