Research on the path to improve the efficiency of government social governance based on data mining technology under the background of carbon neutrality

Using data mining to improve the efficiency of government governance in the context of carbon neutrality is an important way to achieve the modernization of the national governance system. This study starts with the logic of carbon neutral issues, analyzes the factors and indicators that affect the effectiveness of social governance, and constructs the evaluation index system of government social governance efficiency based on data mining application under the background of carbon neutral, including per capita GDP, per capita domestic power consumption of residents, per capita CO2 emissions, per capita green area, industrial waste gas treatment rate, industrial wastewater discharge compliance rate and other indicators, which includes 4 first-class indicators, 19 second-class indicators and 38 third class indicators. Then, the CV-CRITICAL (coefficient of variation critical) index weight determination algorithm is used to determine the index weight. The Pearson correlation coefficient method is used to evaluate the correlation between the two vectors, and then the rationality of the government social governance efficiency evaluation index system based on data mining applications is evaluated. The evaluation results show that the level of social governance effectiveness of the Chinese government is on the rise from 2016 to 2021. This study promotes the application of improving the efficiency of government social governance in the context of carbon neutrality, and provides tools for relevant assessment through data mining technology. This research can not only deepen the theoretical connotation of government governance effectiveness, but also help promote the application of big data in government governance practice

Competitive Repertoire and Coordination of Chinese Horizontal Integrating Firms: Moderating Effects of Market Fragmentation

Because of market fragmentation, nowadays Chinese horizontal integrating firms are in a “two-line battle” competition both against MNEs and local firms. This paper attempted to discuss how can a firm, in such “two-line battle” competition, adopt a suitable competitive repertoire matching with its organizational coordination, and how dose market fragmentation have influence on this matching, if there is any. This paper, by empirically testing Chinese firms from three industries, found out that coordination has a negative moderating effect between complexity of repertoire and performance. Moreover, market fragmentation has weakening impact to the interaction between complexity and coordination. The conclusion enriched the analysis framework of competitive action (or repertoire) decision, and brought better understanding of the impacts of institutional context on firm competitive behavior. Key words: Repertoire; Competitive complexity; Coordination; Market fragmentatio

The evolution of public sentiment toward government management of emergencies: Social media analytics

At present, social media have become the main media of network public opinion (PO) dissemination. By analyzing the trend of emotional development in public emergencies, we can explore the evolution law of PO and identify potential risks, which provide decision support for the guidance and control of government management. First, based on the concept of critical points in the complex system, this study established a public sentiment (PS) evolution model under public emergencies and proposed an algorithm to identify the critical points in PS based on microblog data analysis. In addition, the BC-BIRCH algorithm was used to construct a topic clustering model for public emergencies, which improved the effect of topic discovery by merging multiple topic clusters. The evolution of public emergencies was analyzed by calculating the emotional heat value of different topic events. Finally, experimental results showed that the emotion of netizens' fluctuates greatly in the initial stage of PO under different themes. The method used in this paper achieved good results in topic clustering, critical point prediction, and PO evolution analysis of public emergencies. The main contribution of this paper is to analyze the evolution of the internal mechanism of PS and to identify and predict key nodes such as the outbreak and extinction of netizens' sentiment based on data-driven methods so as to provide the basis and support to the government and related media as the main body of prevention and control to respond in advance and guide in time

Substrate specificity provides insights into the sugar donor recognition mechanism of O-GlcNAc transferase (OGT).

O-Linked β-N-acetylglucosaminyl transferase (OGT) plays an important role in the glycosylation of proteins, which is involved in various cellular events. In human, three isoforms of OGT (short OGT [sOGT]; mitochondrial OGT [mOGT]; and nucleocytoplasmic OGT [ncOGT]) share the same catalytic domain, implying that they might adopt a similar catalytic mechanism, including sugar donor recognition. In this work, the sugar-nucleotide tolerance of sOGT was investigated. Among a series of uridine 5'-diphosphate-N-acetylglucosamine (UDP-GlcNAc) analogs tested using the casein kinase II (CKII) peptide as the sugar acceptor, four compounds could be used by sOGT, including UDP-6-deoxy-GlcNAc, UDP-GlcNPr, UDP-6-deoxy-GalNAc and UDP-4-deoxy-GlcNAc. Determined values of Km showed that the substitution of the N-acyl group, deoxy modification of C6/C4-OH or epimerization of C4-OH of the GlcNAc in UDP-GlcNAc decreased its affinity to sOGT. A molecular docking study combined with site-directed mutagenesis indicated that the backbone carbonyl oxygen of Leu653 and the hydroxyl group of Thr560 in sOGT contributed to the recognition of the sugar moiety via hydrogen bonds. The close vicinity between Met501 and the N-acyl group of GlcNPr, as well as the hydrophobic environment near Met501, were responsible for the selective binding of UDP-GlcNPr. These findings illustrate the interaction of OGT and sugar nucleotide donor, providing insights into the OGT catalytic mechanism