Receiver operating curve (ROC) analysis of CT-proET1, MRproADM, the CT-proET1/MR-proADM ratio and the APACHE II score with respect to outcome prediction of critically ill patients

Receiver operating characteristic (ROC) plots are graphical plots illustrating the sensitivity (-axis) and the specificity ( -axis) for all cut-off points of a diagnostic or prognostic test. The overall performance and a summary measure of the diagnostic accuracy of a test can be expressed as the area under the ROC curve (AUC). Note that an AUCof 0.50 means that the diagnostic accuracy in question is equivalent to that which would be obtained by flipping a coin (i.e., random chance). () Data of all patients ( = 95) with SIRS and sepsis on admission to the ICU. Sensitivity was calculated with nonsurvivors ( = 21), specificity with survivors ( = 74) during their hospital stay. () Data of patients with sepsis (including septic shock) in need for blood pressure support with vasoactiva ( = 30) on admission to the ICU. Sensitivity was calculated with nonsurvivors ( = 9), specificity with survivors ( = 21) during their hospital stay.<p><b>Copyright information:</b></p><p>Taken from "Circulating Precursor Levels of Endothelin-1 and Adrenomedullin, Two Endothelium-Derived, Counteracting Substances, in Sepsis"</p><p></p><p>Endothelium 2007;14(6):345-351.</p><p>Published online 13 Dec 2007</p><p>PMCID:PMC2430170.</p><p></p

CT-proET-1 and MR-proADM values in all patients according to the severity of disease

Patients' data on admission to the ICU were grouped according to the severity of the disease following consensus criteria in groups with “SIRS, but no sepsis,” “sepsis,” and “septic shock.” Squares denote median values and whiskers indicate 25th and 75th percentiles.<p><b>Copyright information:</b></p><p>Taken from "Circulating Precursor Levels of Endothelin-1 and Adrenomedullin, Two Endothelium-Derived, Counteracting Substances, in Sepsis"</p><p></p><p>Endothelium 2007;14(6):345-351.</p><p>Published online 13 Dec 2007</p><p>PMCID:PMC2430170.</p><p></p

Qulity of lipids in foods

The title of the work is "Quality of lipids in food". The work is divided into two parts. The first is theoretical, the other is experimental. The theoretical part is divided into two chapters. The first section describes general chemical composition and properties of lipids. This point is further divided into four sections, which are specifically focused on different groups of lipids. The second theoretical point of attention is focused on the importance of fat in the diet, the synthesis of fatty acids, lipid digestion and issues related to absorbancy and lipid transport. This section also contains a passage which refers to further dietary recommendations, among which highlights the question of the proper quantity and quality of fat contained in food. There are not omitted principles of proper use and storage of fat. The last section of this section deals with dietary supplements and functional foods from which the positive effect on human health is expected. The experimental part is based on chemical analysis of twenty samples of dietary supplements containing n-3 fatty acids. These fatty acids play a vital role in the prevention and treatment of many diseases, especially myocardial infarction or ischemic heart disease. In the screening of these products, attention was focused on the content of..

Additional file 4: of Infection biomarkers in primary care patients with acute respiratory tract infections–comparison of Procalcitonin and C-reactive protein

Biomarker at baseline and day seven as predictors for days with restricted activities or persistence of discomfort after 14 days according to subgroups. LRTI non-pneumonic. (PPTX 86 kb

Cox regression analysis for mortality after 90 days for all patients (n = 441).

<p>CI =  confidence interval; CRP =  C-reactive protein; NIHSS =  National Institutes of Health Stroke Scale; AMI =  acute myocardial infarction.</p

Logistic regression analysis for functional outcome after 90 days for ischemic stroke patients (n = 342).

<p>OR =  odds ratio; CI =  confidence interval; CRP =  C-reactive protein; NIHSS =  National Institutes of Health Stroke Scale; AMI =  acute myocardial infarction.</p

Baseline characteristics of patients with ischemic stroke and transient ischemic attack.

<p>Discrete variables are expressed as frequency (percentage) and continuous Gaussian variables as means with SD and non-Gaussian variables as medians with interquartile ranges [IQR].</p><p>NIHSS =  National Institutes of Health Stroke Scale; AMI =  acute myocardial infarction; TACS =  total anterior circulation syndrome; PACS =  partial anterior circulation syndrome; LACS =  lacunar syndrome; POCS =  posterior circulation syndrome.</p

Study flow chart.

<p>Study flow chart.</p

Logistic regression analysis for functional outcome after one year for ischemic stroke patients (n = 342).

<p>OR =  odds ratio; CI =  confidence interval; CRP =  C-reactive protein; NIHSS =  National Institutes of Health Stroke Scale; AMI =  acute myocardial infarction.</p

Kaplan Meier Survival Curves.

<p>A. Survival in relation to median cortisol level of 475 nmol/L. p = 0.0014, Hazard Ratio 0.35, 95% CI 0.19–0.67. B. Survival in relation to median stimulated cortisol level of 742 nmol/L. p = 0.015, Hazard Ratio 0.4496, 95% CI 0.24–0.86. C. Survival in relation to median dehydroepiandrosterone level of 15.5 nmol/L. p = 0.0236, Hazard Ratio 2.09, 95% CI 1.104 to 3.955. D. Survival in relation to median dehydroepiandrosterone-sulfate level of 2.4 umol/L. p = 0.1490, Hazard Ratio 1.60, 95% CI 0.85–3.80. E. Survival in relation to median cortisol/DHEA level of 27 nmol/nmol. p = 0.0002, Hazard Ratio 0.32, 95% CI 0.17–0.61. F: Survival in relation to median cortisol/DHEAS level of 203 nmol/micromol. p = 0.0004, Hazard Ratio 0.31, 95% CI 0.17–0.59.</p