Membrane-Based Inverse Transition Cycling: An Improved Means for Purifying Plant-Derived Recombinant Protein-Elastin-Like Polypeptide Fusions

Elastin-like peptide (ELP) was fused to two different avian flu H5N1 antigens and expressed in transgenic tobacco plants. The presence of the ELP tag enhanced the accumulation of the heterologous proteins in the tobacco leaves. An effective membrane-based Inverse Transition Cycling was developed to recover the ELPylated antigens and antibodies from plant material. The functionality of both the ELPylated neuraminidase and an ELPylated nanobody was demonstrated

Further Discussion On Educational Issues And Case Teaching Method For Economic Students Via Case Studies

Vietnam has begun to apply case stude method teaching for economic and business students in clleges and universities because it has provided them with real situation and problem solving skills. By using experiences, synthesis and quantitative methods ombined with dialectical materialism methods, this study prove examples of case studies in Bahrain and in Vietnam, in the context og educationin globalization, it is better to propose innovative educational methods for strengthening educational policies and for educating studets also, for instance, in economic field. In developing countries such as Vietnam, in Asia and in the world, case teaching method has been usedf widely for economic major students in clooges and unievrsities. Therefore, This study will menitone case method benefits such as real worl problems, solvin gproblem skill enhancement and representative and ttractiveness for learning

Impact of electronic word of mouth to the purchase intention - the case of Instagram

This research aims to discover and confirm the factors of e-WOM that influence users' shopping intentions on Instagram. The data was collected from 700 customers who belong to Gen Y and Gen Z from 18 to 39 years old who live and work in Vietnam. The research model and the scales were built from the empirical research of e-WOM from Lim (2016); Park et al. (2007); Prendergast et al. (2010). Quantitative methods were performed by Cronbach's Alpha reliability testing, EFA discovery factor analysis, regression, and ANOVA test. The research results showed that the fourth factor of e-WOM positively impacts users' purchase intent on Instagram with decreasing levels as Information Provider's Expertise, the quantity of e-WOM, and the Source credibility of e-WOM, and the quality of e-WOM, respectively. Also, users' purchase intention on Instagram under the impact of e-WOM varies by gender, but there is no difference by age and income

On the Effectiveness of Adversarial Samples against Ensemble Learning-based Windows PE Malware Detectors

Recently, there has been a growing focus and interest in applying machine learning (ML) to the field of cybersecurity, particularly in malware detection and prevention. Several research works on malware analysis have been proposed, offering promising results for both academic and practical applications. In these works, the use of Generative Adversarial Networks (GANs) or Reinforcement Learning (RL) can aid malware creators in crafting metamorphic malware that evades antivirus software. In this study, we propose a mutation system to counteract ensemble learning-based detectors by combining GANs and an RL model, overcoming the limitations of the MalGAN model. Our proposed FeaGAN model is built based on MalGAN by incorporating an RL model called the Deep Q-network anti-malware Engines Attacking Framework (DQEAF). The RL model addresses three key challenges in performing adversarial attacks on Windows Portable Executable malware, including format preservation, executability preservation, and maliciousness preservation. In the FeaGAN model, ensemble learning is utilized to enhance the malware detector's evasion ability, with the generated adversarial patterns. The experimental results demonstrate that 100\% of the selected mutant samples preserve the format of executable files, while certain successes in both executability preservation and maliciousness preservation are achieved, reaching a stable success rate

The relationship between brand equity and intention to buy: the case of convenience stores

The research aims to identify the components of brand equity that affect consumer purchasing intentions and measure the effect of brand equity components on the intention of consumer purchases at the convenience stores in Ho Chi Minh City. The authors conduct the group discussions, expert discussion, and then analyze data from 200 valid questionnaires with four components of brand equity, namely perceived quality, brand loyalty, brand association, brand awareness. The results of Exploratory Factor Analysis (EFA) show that all four elements have a positive effect on the customer' intention to purchase in the convenience store of Ho Chi Minh City. In particular, the brand association factor has the strongest influence, followed by perceived quality, brand awareness, and brand loyalty. This research contributes that the results confirm the theory of Aaker (1991), Brown and Stayman (1992), Cobb-Walgren et al. (1995), MacKenzie (1986) in the new context of convenience stores in Ho Chi Minh City, Vietnam. Besides, the study gives some recommendations to help convenience stores improve the elements of brand equity and it, to enhance attraction for consumers

Applied bioinformatics tools for analysis of Microrna-214 expression and prediction of its potential targets genes in Nasopharyngeal carcinoma

miRNA (microRNA) are short RNA molecules in length from 20 to 24 nucleotides that have been shown to play an important role in regulating gene expression in many different types of human cancer. Meanwhile, miRNA-214 is one of the known miRNAs involved in the formation of nasopharyngeal carcinoma (NPC) through overexpression that promotes proliferation and development of cancer cells. However, in Vietnam, the study of miR-214 related to NPC has not been conducted yet. With the aims to develop the further studies of miR-214 on NPC in Vietnamese patients, in this initial study, we conducted the analysis of miR-214 expression in previous publications, as well as the prediction of miR-214 potential target genes, which involved in many cellular pathways. Here we applied bioinformatics tools to predict miRNAs and their targets, and discuss the role of miR-214 in the context of human cancers. As the results, miR-214 acted as the oncogenic roles in NPC, relevanted to many pathways, such as cell proliferation, apoptosis, metastasis and invasion through the its target genes LTF, Bim, Bax, LINC0086, etc. In conclusion, the use of computional approaches facilitate the further experimental validation of miRNAs in general, particularly miR-214, in Vietnamese NPC patients

Academic Anxiety of Vietnamese Secondary School Students as a Reason for Applying Online Learning

Academic anxiety is one of the major problems in student psychology across the world. It applies equally to students of all ages, from elementary school to college and university students. Research shows that learning online is an effective way to defuse feelings of academic anxiety. Elimination of anxiety is clearly visible regardless of age, gender, or prior online learning experience. The study aims to identify academic anxiety as one of the most important reasons for moving to online learning or blended learning in secondary school. The study investigated academic anxiety among secondary school students in Vietnam. After surveying 677 students in classroom learning, the results showed that 13.7% of secondary students suffered from frequent anxiety, and 3.0% of them suffered from very frequent anxiety. Lower anxiety was observed among students actively participated in-class activities, and students with excellent academic performance. These factors can be optimally enhanced through blended and online learning. There were no differences in academic anxiety among male and female students, urban and rural students. There was a moderate correlation between a student's anxiety level and pressure of the school, parental expectations, students' motivation for high performance, and especially, among students who have the melancholic temperament. And the influence of these negative factors can also be optimally reduced with the help of online learning. Regression model could provide useful suggestions for parents, teachers and students in reducing academic anxiety for students, including the use of full or blended online learning

ASSESSMENT OF GEOMORPHIC PROCESSES AND ACTIVE TECTONICS IN CON VOI MOUNTAIN RANGE AREA (NORTHERN VIETNAM) USING THE HYPSOMETRIC CURVE ANALYSIS METHOD

the Day Nui Con Voi (DNCV) area of Vietnam. For this purpose, a spatial database was collected and constructed, including DEM (Digital Elevation Model) and a geological map. The hypsometric curve (HC) analysis method and its statistical moments were adopted to use for the assessment. These methods have been widely used for the assessment of geomorphic processes and active tectonics in many areas in the world showing promising results. A total of 44 sub-basins of the Red River and the Chay river were analyzed. The result shows that 3 curve-types such as "straight- shape", "S- shape", and concave were found; with the concave curve being the dominant and widely distributed in the northeast side and in the south of the southwestern side of the study area. The hypsometric integral (HI) values are rather small with the largest value is 0.37 and the smallest one is 0.128. Other statistical moments of the hypsometric curve, i.e. skew (SK), kurtosis (KUR), and the density function (density skew - DSK and density kurtosis-DKUR) show great values, which increased in the south direction of the area study. Accordingly, recent active tectonics (uplift-lower) in the study area is generally weak; however, they are also not completely homogeneous and can be distinguished by different levels. The southwestern side is being lifted higher than the northeastern side. The northern part is being lifted larger than the southern part. In the region, the uplift activities were increased gradually in the Pliocene-Quaternary and could have stopped at certain time in the past. The current geomorphic processes are mainly headward erosion in the upstream.References Allen, C.R., Gillepie, A.R., Han, Y., Sieh, K.E., Zhu, C., 1984. 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Ice formation in the Arctic during summer: false-bottoms

The only source of ice formation in the Arctic during summer is a layer of ice called false-bottoms between an under-ice melt pond and the underlying ocean. Of interest is to give a mathematical model in order to determine the simultaneous growth and ablation of false-bottoms, which is governed by both of heat fluxes and salt fluxes. In one dimension, this problem may be considered mathematically as a two-phase Stefan problem with two free boundaries. Our main result is to prove the existence and uniqueness of the solution from the initial condition.Comment: 22 page