An Analysis of Korea-Vietnam Bilateral Trade Relation

Republic of Korean – Vietnam relation has been rapidly deepened in all fields, especially trade and investment since the establishment of diplomatic ties in 1992. This paper analyzes the patterns and trends in the trade relations between the two countries in the past twenty years. Various trade indices such as Trade intensity, Trade complementarities, Intra industry and Revealed comparative advantages were used to describe the structure and composition in the Korea-Vietnam bilateral trade. The study results show that trade pattern between Korea and Vietnam is predominantly inter-industry trade and complementary. The main findings also suggest that there is significant potential for further growth of trade between two countrie

3D surface reconstruction using dense optical flow combined to feature matching: Application to endoscopy

International audienceIn structure from motion (SfM) algorithms, the surface reconstruction performance strongly depends on the quality of the determination of homologous points between images. Classical feature matching-based methods as integrated in the state-of the-art SfM-algorithms are often inoperative for scenes including weak structures and textures (e.g., as those in medical endoscopic videos). This contribution introduces an effective solution based on the combination of dense optical flow and feature matching. The accuracy and robustness of the proposed method were validated using results obtained for a phantom with known dimensions and with patient data, respectively. Apart from the high performance obtained for cystoscopy and gastroscopy, the proposed solution has a high potential in other medical and non-medical scenes.Dans les algorithmes de structures à partir du mouvement (SfM), la performance de la reconstruction des surfaces dépend fortement de la qualité de la détermination des points homologues entre images. Les méthodes SfM de référence sont souvent inopérantes pour les scènes avec peu de structures et textures faiblement contrastées car elles reposent uniquement sur l'appariement de caractéristiques. Cette contribution présente une solution associant un flot optique dense à la mise en correspondance de caractéristiques. La précision et la robustesse de la reconstruction ont été validées via des résultats obtenus pour un fantôme avec des dimensions connues et avec des données patient en cystoscopie et en gastroscopie, respectivement. Plus généralement, cette approche a un fort potentiel pour toute scène peu constrastée, médicales ou non

Optimal linear quadratic Gaussian control based frequency regulation with communication delays in power system

In this paper, load frequency regulator based on linear quadratic Gaussian (LQG) is designed for the MAPS with communication delays. The communication delay is considered to denote the small time delay in a local control area of a wide-area power system. The system is modeled in the state space with inclusion of the delay state matrix parameters. Since some state variables are difficult to measure in a real modern multi-area power system, Kalman filter is used to estimate the unmeasured variables. In addition, the controller with the optimal feedback gain reduces the frequency spikes to zero and keeps the system stable. Lyapunov function based on the LMI technique is used to re-assure the asymptotically stability and the convergence of the estimator error. The designed LQG is simulated in a two area connected power network with considerable time delay. The result from the simulations indicates that the controller performed with expectation in terms of damping the frequency fluctuations and area control errors. It also solved the limitation of other controllers which need to measure all the system state variables

Village Baseline Study – Site Analysis Report for My Loi, Ky Anh district, Ha Tinh province – Viet Nam

Data collection for the Village Baseline Study (VBS) of My Loi village in the CCAFS benchmark site of central Viet Nam took place on 17- 19 October 2014. Focus group discussions were conducted separately for 45 men and 45 women villagers.. The VBS had three main topics: map of (1) community resources, (2) organizational landscapes, and (3) information networks. A seminar was held in December 2014 to seek participants’ feedback. My Loi village has experienced multiple extreme weather events (temperature and water stresses, storms and typhoons) throughout the years. The main constraints for agricultural development and livelihoods are limited water resources and poor conditions of irrigation systems, which are challenges to improving the agricultural production situation. Moreover, sand and rock mining have caused water pollution, erosion on riverbanks and loss of farmland area. Another constraint is marketing, as villagers are not aware of any organization involved in finding outlets for agricultural products. The potentials for developing innovative climate-smart solutions in the village are several: farmers have experiences and are interested in trying new varieties and adjusting farming calendars to improve the situation. Livestock expansion and agroforests/reforestation hold opportunities for improving household incomes. Furthermore, at least half of the organisations identified in the region are working to address food security issues

Pre-treatment potential of electro-coagulation process using aluminum and titanium electrodes for instant coffee processing wastewater

This study aimed at investigating the potential of electrocoagulation (EC) process using Al-Al and Al-Ti electrodes for the pre-treatment of instant coffee processing wastewater. Effects of various operating conditions, including cell voltage, time of treatment, inter-electrode distance, pH of solution, solution conductivity and agitation speed on the removals of chemical oxygen demand (COD) and color were considered. The maximum removal of COD and color was achieved at 87% and 99%, respectively, corresponding to COD and color in the effluents of 359-384 mg/L and 58-101 Pt-Co. Biodegradability of treated wastewater was significantly improved since BOD5/COD increased from initial value of 0.42 to 0.65 after treatment. Nether mixing nor adding of electrolyte was recommended. Moreover, the COD removal kinetics during EC process appeared to follow the first-order kinetic model. The operating costs were also determined as a reference for cost assessment of the treatment

Prevalence of HBV infection among different HIV-risk groups in Hai Phong, Vietnam

金沢大学医薬保健研究域医学系Hepatitis B virus (HBV) infection in Hai Phong, northern Vietnam, was characterized by analyzing the prevalence and genotype distribution of HBV as well as co-infection with human immunodeficiency virus type 1 (HIV-1) among five different risk groups for HIV infection. Plasma samples were collected from intravenous drug users (n=760, anti-HIV-1 antibody positive rate: 35.9%), female sex workers (FSWs; n=91, 23.1%), seafarers (n=94, 0%), pregnant women (n=200, 0.5%), and blood donors (n=210, 2.9%) in 2007 [Ishizaki et al. (2009): AIDS Res Hum Retroviruses 25:175-182]. Samples were screened for the hepatitis B surface antigen (HBsAg) and anti-HBs antibody and analyzed genetically. The cumulative HBV incidence rate (HBsAg+anti-HBs) was 53.2% (10.7+42.5%) in intravenous drug users, 51.6% (11.0+40.6%) in FSWs, 54.3% (9.6+44.7%) in seafarers, 50.5% (12.5+38.0%) in pregnant women, and 51.0% (18.1+32.9%) in blood donors; there was no significant difference among these groups. Of 163 HBsAg-positive samples, 113 could be analyzed genetically. Phylogenetic analysis, based on the preS1 region, revealed genotype B4 was most prevalent (90/113; 79.6%), followed by C1 (17.7%), I1 (1.8%), and B2 (0.9%). There was no significant difference in HBV genotype distribution among different HIV infection-risk groups. The prevalence of HBsAg was 10.3% (31/301) in HIV-1-infected individuals and 12.5% (132/1,054) in non-HIV-1-infected individuals, which was not significant. In addition, no significant difference in HBV genotype distribution was observed between HBV/HIV-1 co-infected and HBV mono-infected groups. These results suggest that, although HBV and HIV-1 share modes of transmission, major transmission routes of HBV have been different from those of HIV-1 in Hai Phong, Vietnam. J. Med. Virol. 83:399-404, 2011. © 2011 Wiley-Liss, Inc

Effect of a 2+1 schedule of ten-valent versus 13-valent pneumococcal conjugate vaccine on pneumococcal carriage: Results from a randomised controlled trial in Vietnam.

BACKGROUND: Pneumococcal conjugate vaccines (PCVs) generate herd protection by reducing nasopharyngeal (NP) carriage. Two PCVs, PCV10 and PCV13, have been in use for over a decade, yet there are few data comparing their impact on carriage. Here we report their effect on carriage in a 2+1 schedule, compared with each other and with unvaccinated controls. METHODS: Data from four groups within a parallel, open-label randomised controlled trial in Ho Chi Minh City contribute to this article. Three groups were randomised to receive a 2+1 schedule of PCV10 (n = 250), a 2+1 schedule of PCV13 (n = 251), or two doses of PCV10 at 18 and 24 months (controls, n = 197). An additional group (n = 199) was recruited at 18 months to serve as controls from 18 to 24 months. NP swabs collected at 2, 6, 9, 12, 18, and 24 months were analysed (blinded) for pneumococcal carriage. This study aimed to determine if PCV10 and PCV13 have a differential effect on pneumococcal carriage, a secondary outcome of the trial. We also describe the serotype distribution among unvaccinated participants. TRIAL REGISTRATION: ClinicalTrials.gov NCT01953510. FINDINGS: Compared with unvaccinated controls, a 2+1 schedule of PCV10 reduced PCV10-type carriage by 45-62% from pre-booster through to 24 months of age, and a 2+1 schedule of PCV13 reduced PCV13-type carriage by 36-49% at 12 and 18 months of age. Compared directly with each other, there were few differences between the vaccines in their impact on carriage. Vaccine serotypes accounted for the majority of carriage in unvaccinated participants. INTERPRETATION: Both PCV10 and PCV13 reduce the carriage of pneumococcal vaccine serotypes. The introduction of either vaccine would have the potential to generate significant herd protection in this population. FUNDING: National Health and Medical Research Council of Australia, Bill & Melinda Gates Foundation

Efficacy against pneumococcal carriage and the immunogenicity of reduced-dose (0 + 1 and 1 + 1) PCV10 and PCV13 schedules in Ho Chi Minh City, Viet Nam: a parallel, single-blind, randomised controlled trial

Background Interest in reduced-dose pneumococcal conjugate vaccine (PCV) schedules is growing, but data on their ability to provide direct and indirect protection are scarce. We evaluated 1 + 1 (at 2 months and 12 months) and 0 + 1 (at 12 months) schedules of PCV10 or PCV13 in a predominately unvaccinated population. Methods In this parallel, single-blind, randomised controlled trial, healthy infants aged 2 months were recruited from birth records in three districts in Ho Chi Minh City, Vietnam, and assigned (4:4:4:4:9) to one of five groups: PCV10 at 12 months of age (0 + 1 PCV10), PCV13 at 12 months of age (0 + 1 PCV13), PCV10 at 2 months and 12 months of age (1 + 1 PCV10), PCV13 at 2 months and 12 months of age (1 + 1 PCV13), and unvaccinated control. Outcome assessors were masked to group allocation, and the infants' caregivers and those administering vaccines were not. Nasopharyngeal swabs collected at 6 months, 12 months, 18 months, and 24 months were analysed for pneumococcal carriage. Blood samples collected from a subset of participants (200 per group) at various timepoints were analysed by ELISA and opsonophagocytic assay. The primary outcome was the efficacy of each schedule against vaccine-type carriage at 24 months, analysed by intention to treat for all those with a nasopharyngeal swab available. This trial is registered at ClinicalTrials.gov, NCT03098628. Findings 2501 infants were enrolled between March 8, 2017, and July 24, 2018 and randomly assigned to study groups (400 to 0 + 1 PCV10, 400 to 0 + 1 PCV13, 402 to 1 + 1 PCV10, 401 to 1 + 1 PCV13, and 898 to control). Analysis of the primary endpoint included 341 participants for 0 + 1 PCV10, 356 0 + 1 PCV13, 358 1 + 1 PCV10, 350 1 + 1 PCV13, and 758 control. At 24 months, a 1 + 1 PCV10 schedule reduced PCV10-type carriage by 58% (95% CI 25 to 77), a 1 + 1 PCV13 schedule reduced PCV13-type carriage by 65% (42 to 79), a 0 + 1 PCV10 schedule reduced PCV10-type carriage by 53% (17 to 73), and a 0 + 1 PCV13 schedule non-significantly reduced PCV13-type carriage by 25% (–7 to 48) compared with the unvaccinated control group. Reactogenicity and serious adverse events were similar across groups. Interpretation A 1 + 1 PCV schedule greatly reduces vaccine-type carriage and is likely to generate substantial herd protection and provide some degree of individual protection during the first year of life. Such a schedule is suitable for mature PCV programmes or for introduction in conjunction with a comprehensive catch-up campaign, and potentially could be most effective given as a mixed regimen (PCV10 then PCV13). A 0 + 1 PCV schedule has some effect on carriage along with a reasonable immune response and could be considered for use in humanitarian crises or remote settings. Funding Bill & Melinda Gates Foundation. Translation For the Vietnamese translation of the abstract see Supplementary Materials section

An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis

Background: Cryptococcal meningitis has high mortality. Flucytosine is a key treatment but is expensive and rarely available. The anti-cancer agent tamoxifen has synergistic anti-cryptococcal activity with amphotericin in vitro. It is off-patent, cheap, and widely available. We performed a trial to determine its therapeutic potential. Methods:Open label randomized controlled trial. Participants received standard care - amphotericin combined with fluconazole for the first two weeks - or standard care plus tamoxifen 300mg/day. The primary end point was Early Fungicidal Activity (EFA) - the rate of yeast clearance from cerebrospinal fluid (CSF). Trial registration https://clinicaltrials.gov/ct2/show/NCT03112031 . Results: 50 patients were enrolled, (median age 34 years, 35 male). Tamoxifen had no effect on EFA (- 0.48log10 colony-forming units/mL/CSF control arm versus -0.49 tamoxifen arm, difference - 0.005log10CFU/ml/day, 95%CI: -0.16, 0.15, P=0.95). Tamoxifen caused QTc prolongation. Conclusion: High dose tamoxifen does not increase the clearance rate of Cryptococcus from CSF. Novel, affordable therapies are needed. Funding:The trial was funded through the Wellcome Trust Asia Programme Vietnam Core Grant 106680 and a Wellcome Trust Intermediate Fellowship to JND grant number WT097147MA