Zementaugmentation bei Wirbelmetastasen (Vertebro- und Kyphoplastie)

Zusammenfassung: Pathologische Wirbelfrakturen bei Metastasen oder im Rahmen eines multiplen Myeloms können mittels einer Zementaugmentation (Vertebro- oder Kyphoplastie) effizient stabilisiert werden. Die Indikationsstellung beschränkt sich auf Läsionen im Wirbelkörper, sobald die posterioren Elemente involviert sind genügt eine Zementierung nicht mehr, ebenso wenn eine Spinalkanaleinengung/Neurokompression vorhanden ist. Technisch wird gleich verfahren wie bei der osteoporotischen Fraktur - das Extravasationsrisiko ist aber erheblich größer und die klinischen Ergebnisse sind nicht so uniform positiv wie bei Osteoporosefrakturen. Die Zementaugmentation per se ist keine Tumorbehandlung sondern eine Stabilisierung des Wirbels. Osteolysen ohne mechanische Kompromittierung brauchen keine Augmentation. Die Patientenbetreuung sollte interdisziplinär vernetzt erfolge

Marketing plan for the touristic product: The Samadai Dolphin House

The Samadai Dolphin House is a reef in the region of Marsa Alam in Egypt declared as a nature preserve. As its name suggests, the main activities at the site are snorkeling and diving with wild dolphins. In January 2013, an Egyptian non-governmental organization named the Hurghada Environmental Protection and Conservation Association (HEPCA) took over the management of this touristic site and has the obligation to sell 200 tickets per month. Documents received by HEPCA and surveys conducted with some diving centers show that most of the visitors who come to see the Samadai Dolphin House are of Italian and German nationalities. They tend to prefer the snorkeling excursions and enjoy the quality of information provided by the guides. HEPCA is working closely with the numerous diving centers that offer this excursion as they are the service providers and at the same time the competitors (by proposing other similar excursions). By implementing a better communication and promotional strategy, the purpose of this thesis is to increase sales for the Samadai Dolphin House in order to generate revenues for the protection and the conservation of this site

Physicians' knowledge and continuing medical education regarding fitness to drive: a questionnaire-based survey in Southeast Switzerland

Valid information for physicians in Switzerland concerning knowledge and continuing education in traffic medicine is not available. Also, their attitude to the legally prescribed periodic driving fitness examinations is unclear. In order to gain more information about these topics, 635 resident physicians in Southeast Switzerland were sent a questionnaire (response rate 52%). In a self-estimation, 79% of the queried physicians claimed to know the minimal medical requirements for drivers which are important in their specialty. Statistically significant differences existed between the specialties, whereby general practitioners most frequently claimed to know the minimal medical requirements (90%). It appears that the minimal medical requirements for drivers are well known to the queried physicians. Fifty-two percent of the physicians favored an expansion of continuing education in traffic medicine. Such an expansion was desired to a lesser extent by physicians without knowledge of the minimal requirements (p < 0.001). A clear majority of the medical professionals adjudged the legally prescribed periodic driving fitness examinations as being an expedient means to identify unfit drivers. A national standardized form for reporting potentially unfit drivers to the licensing authorities was supported by 68% of the responding physicians. Such a form could simplify and standardize the reports to the licensing authoritie

Discretionary medical reporting of potentially unfit drivers: a questionnaire-based survey in Southeast Switzerland

In Switzerland, every physician has the right to report a patient that is potentially unfit to drive to the licensing authority without violating medical confidentiality. Verified information regarding physicians' attitudes concerning this discretionary reporting and the frequency of such reports are not available. In order to answer these questions, 635 resident physicians were sent a questionnaire. The response rate was 52%. On average, the responding physicians—for all specialties—reported 0.31 patients (SD 0.64, 95% CI 0.24-0.38) in the year before the survey and 1.00 patient (SD 1.74, 95% CI 0.81-1.20) in the past 5years. Seventy-nine percent of the responding physicians indicated knowing the current legal requirements for driving in Switzerland. In applied logistic regression analysis, only two factors correlate significantly with reporting: male sex (odds ratio 5.4) and the specialty "general medicine” (odds ratio 3.4). Ninety-seven percent of the physicians were against abolishing medical discretionary reporting and 29% were in favor of introducing mandatory reporting. The great majority of the questioned physicians supported the discretionary reporting of drivers that are potentially unfit to drive as currently practiced in Switzerland. The importance and the necessity of a regular traffic medicine-related continuing education for medical professionals are shown by the low number of reports per physicia

Time-resolved charge detection with cross-correlation techniques

We present time-resolved charge sensing measurements on a GaAs double quantum dot with two proximal quantum point contact (QPC) detectors. The QPC currents are analyzed with cross-correlation techniques, which enables us to measure dot charging and discharging rates for significantly smaller signal-to-noise ratios than required for charge detection with a single QPC. This allows to reduce the current level in the detector and therefore the invasiveness of the detection process and may help to increase the available measurement bandwidth in noise-limited setups.Comment: 6 pages, 4 figure

Arktisches Wissen

Als sich der Wettlauf um Nordwestpassage und Nordpol im frühen 20. Jahrhundert verschärfte, suchte die dänische Administration Grönlands nach Verbündeten. Als Zulieferer kolonialen Wissens rekrutierte sie Schweizer Naturforscher, die sich ihrerseits als nationale Polarhelden vermarkteten. An welche Auflagen waren die Forschungsreisenden aus der Schweiz in der Arktis gebunden? Wie kontrollierte die dänische Handelsgesellschaft den Kontakt der Außenseiter zur lokalen Bevölkerung, den Inuit? Wer finanzierte die Expeditionen? Lea Pfäffli erzählt eine transimperiale Geschichte arktischen Wissens und leuchtet dabei Kolonialreich und Nation neu aus. https://creativecommons.org/licenses/by/4.0

Towards a multicentric quality framework for legal information portals: An application to the DACH region

Legal Information Portals (LIPs) are central information offerings that give various user groups digital access to the law, including legislation, legal acts, or even court decisions. LIPs could provide access to complex legal content in a user-friendly yet accurate way, while exploiting the benefits of open data to enable easy access to legal content for other applications. However, the development of LIPs traditionally adheres to formal legal criteria, leaving users out in the cold. As a result, even the most modern LIPs fall short of providing a user-centric offering. To address this issue, we present a multicentric quality framework to help providers develop and evaluate LIPs by assessing their data quality, data portability, and usability. We apply the framework to the LIPs of Germany, Austria, and Switzerland (the DACH region: D: Deutschland [Germany], A: Austria, CH: Confoederatio Helvetica [Switzerland]) to illustrate its use and identify quality differences between their current systems. Our quality framework for LIPs helps decision-makers better understand and exploit the possibilities for the dissemination of legal information as part of their open justice initiatives. We contribute to the literature by complementing previous conceptual works with a concrete, comprehensive measurement schema that also serves as a basis for assessing user requirements and data portability configurations in other domains with high content complexity