Spectral analysis of a large sample of BeppoSAX Seyfert spectra with Comptonization models: Preliminary results

We present preliminary results of the spectral analysis of a large sample of Seyfert galaxies observed by BeppoSAX. The only selection criterium was a sufficiently large S/N ratio (>10) in the PDS band (12-200 keV) to allow good detection up to the highest energy. The resulting sample is composed of 28 objects (17 Seyfert 1, 11 Seyfert 2) and 50 observations. Our main effort here is to adopt Comptonization models to fit the different spectra on a truly broad band basis (0.1-200 keV). We use two distinct disc-corona configurations, an anisotropic slab and an isotropic spherical one. We discuss the distributions of the physical parameters, like temperature and optical depth of the corona and the reflection component, among this sample. We also discussed the existence (or inexistence) of correlations between these parameters.Comment: 4 pages, 2 figures. Proc. of the meeting: "The Restless High-Energy Universe" (Amsterdam, The Netherlands), E.P.J. van den Heuvel, J.J.M. in 't Zand, and R.A.M.J. Wijers Ed

Novel genes and novel pathogenetic mechanisms in adult-onset primary dystonia

No abstract availabl

Genetic issues in the diagnosis of dystonias

Dystonias are heterogeneous hyperkinetic movement disorders characterized by involuntary muscle contractions which result in twisting and repetitive movements and abnormal postures. Several causative genes have been identified, but their genetic bases still remain elusive. Primary Torsion Dystonias (PTDs), in which dystonia is the only clinical sign, can be inherited in a monogenic fashion, and many genes and loci have been identified for autosomal dominant (DYT1/TOR1A; DYT6/THAP1; DYT4/TUBB4a; DYT7; DYT13; DYT21; DYT23/CIZ1; DYT24/ANO3; DYT25/GNAL) and recessive (DYT2; DYT17) forms. However most sporadic cases, especially those with late-onset, are likely multifactorial, with genetic and environmental factors interplaying to reach a threshold of disease. At present, genetic counseling of dystonia patients remains a difficult task. Recently non-motor clinical findings in dystonias, new highlights in the pathophysiology of the disease, and the availability of high-throughput genome-wide techniques are proving useful tools to better understand the complexity of PTD genetics. We briefly review the genetic basis of the most common forms of hereditary PTDs, and discuss relevant issues related to molecular diagnosis and genetic counseling

Relevant results from the NA48 experiment

We report relevant results from NA48 experiment at CERN SPS. NA48 was proposed in 1990 \cite{proposal} to study direct CP violation in $K^0\to\pi\pi$ to a level of accuracy sufficient to resolve the inconclusive status left by the previous measurements performed by NA31 \cite{NA31} and E731 \cite{E731}. In 2002 NA48 published the final result \cite{NA48epsoeps}. Small modification to the experimental setup have allowed NA48 to go forward with an extensive investigation of $K^0$ rare decays and hyperon decays. Some results are already available and reported here together with the final CP violation measurement.Comment: 3 pages, 1 eps figure, XXIII Physics in collisio

KIC 9821622: An interesting lithium-rich giant in the Kepler field

We report the discovery of a new exceptional young lithium-rich giant, KIC 9821622, in the \textit{Kepler} field that exhibits an unusually large enhancement of $\alpha$, Fe-peak, and \textit{r}-process elements. From high-resolution spectra obtained with GRACES at Gemini North, we derived fundamental parameters and detailed chemical abundances of 23 elements from equivalent widths and synthesis analysis. By combining atmospheric stellar parameters with available asteroseismic data, we obtained the stellar mass, radius, and age. The data analysis reveals that KIC 9821622 is a Li-rich (A(Li)$_{NLTE}$ = 1.80 $\pm$ 0.2) intermediate-mass giant star ($M$ = 1.64 $M_{\odot}$) located at the red giant branch near the luminosity bump. We find unexpectedly elevated abundances of Fe-peak and \textit{r}-process elements. In addition, as previously reported, we find that this is a young star (2.37 Gyr) with unusually high abundances of $\alpha$-elements ([$\alpha$/Fe] = 0.31). The evolutionary status of KIC 9821622 suggests that its Li-rich nature is the result of internal fresh Li that is synthesized through the Cameron-Fowler mechanism near the luminosity bump. However, its peculiar enhancement of $\alpha$, Fe-peak, and \textit{r}-process elements opens the possibility of external contamination by material enriched by a supernova explosion. Although it is less likely, planet accretion cannot be ruled out.Comment: Letter, 6 pages, 3 figures, Accepted for publication in A&A. - Some language editing include

Signatures of rocky planet engulfment in HAT-P-4. Implications for chemical tagging studies

Aims. To explore the possible chemical signature of planet formation in the binary system HAT-P-4, by studying abundance vs condensation temperature Tc trends. The star HAT-P-4 hosts a planet detected by transits while its stellar companion does not have any detected planet. We also study the Lithium content, which could shed light on the problem of Li depletion in exoplanet host stars. Conclusions. The exoplanet host star HAT-P-4 is found to be ~0.1 dex more metal rich than its companion, which is one of the highest differences in metallicity observed in similar systems. This could have important implications for chemical tagging studies, disentangling groups of stars with a common origin. We rule out a possible peculiar composition for each star as lambda Boo, delta Scuti or a Blue Straggler. The star HAT-P-4 is enhanced in refractory elements relative to volatile when compared to its stellar companion. Notably, the Lithium abundance in HAT-P-4 is greater than in its companion by ~0.3 dex, which is contrary to the model that explains the Lithium depletion by the presence of planets. We propose a scenario where, at the time of planet formation, the star HAT-P-4 locked the inner refractory material in planetesimals and rocky planets, and formed the outer gas giant planet at a greater distance. The refractories were then accreted onto the star, possibly due to the migration of the giant planet. This explains the higher metallicity, the higher Lithium content, and the negative Tc trend detected. A similar scenario was recently proposed for the solar twin star HIP 68468, which is in some aspects similar to HAT-P-4. We estimate a mass of at least Mrock ~ 10 Mearth locked in refractory material in order to reproduce the observed Tc trends and metallicity.Comment: 5 pages, 6 figures, A&A Letters accepte

Effect of insulin glargine on cardiovascular risk analysed by mean HRV

Type 2 diabetes mellitus is an insidious disease that is increasingly present in geriatric population [1]. The greatest difficulty is represented by glycaemic control in geriatric patients often not very compliant with diet therapy and drug therapy. A new insulin glargine 300 units/ml formulation seems im- prove patient compliance due to the lower volume of insulin to be injected and improved glycaemic control over 24 hours. The HRV signal, derived from digital electrocardiographic recording, is the simplest and most imme- diate analysis that consists in calculating some temporal parameters [2]. HRV is a simple statistics derived from beat-beat intervals of sinus origin expressed as units of time in milliseconds. Data in the literature indicate that a decrease in HRV, measured with time domain analysis, denotes a worse prognosis and/or an increased risk of mortality in patients with heart disease, especially in the elderly ones