76 research outputs found

    Korelacija između sadržaja titana u čeliku i elektromagnetskih svojstava neorijentiranih elektrolimova

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    In this study the correlation between the titanium content of steel and the core loss of non-oriented electrical steel sheets was determined. The core loss and titanium content of steel have a weak, but positive, correlation. The core loss was found to increase with an increasing titanium content. The study included a statistical analysis of an industrial data set and a metallographic analysis of the titanium inclusions. The analyzed titanium inclusions in the electrical steel sheets containing 0,006 mas.% Ti and 0,008 mas.% Ti were complex oxycarbonitrides, complex TiC and complex Ti(C,N).U radu se opisuje korelacija između sadržaja titana u čeliku i elektromagnetskih svojstava neorijentiranih elektrolimova. Postoji relativno niski stupanj pozitivne korelacije između magnetskih gubitaka i sadržajem titana. Magnetski gubici rastu sa sadržajem titana u čeliku. Izvedena je statistička analiza podataka za limove industrijske proizvodnje i metalografska analiza titanovih uključaka. Analizirani uključci u elektrolimovima sa 0,006 mas.% Ti i 0,008 mas.% Ti bili su kompleksni oksikarbonitridi, kompleksni TiC i kompleksni Ti(C,N)

    Korelacija između sadržaja titana u čeliku i elektromagnetskih svojstava neorijentiranih elektrolimova

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    In this study the correlation between the titanium content of steel and the core loss of non-oriented electrical steel sheets was determined. The core loss and titanium content of steel have a weak, but positive, correlation. The core loss was found to increase with an increasing titanium content. The study included a statistical analysis of an industrial data set and a metallographic analysis of the titanium inclusions. The analyzed titanium inclusions in the electrical steel sheets containing 0,006 mas.% Ti and 0,008 mas.% Ti were complex oxycarbonitrides, complex TiC and complex Ti(C,N).U radu se opisuje korelacija između sadržaja titana u čeliku i elektromagnetskih svojstava neorijentiranih elektrolimova. Postoji relativno niski stupanj pozitivne korelacije između magnetskih gubitaka i sadržajem titana. Magnetski gubici rastu sa sadržajem titana u čeliku. Izvedena je statistička analiza podataka za limove industrijske proizvodnje i metalografska analiza titanovih uključaka. Analizirani uključci u elektrolimovima sa 0,006 mas.% Ti i 0,008 mas.% Ti bili su kompleksni oksikarbonitridi, kompleksni TiC i kompleksni Ti(C,N)

    The Influence of Copper on the Microtexture of Fe-Si-Al Alloys for Non-Oriented Electrical Sheets

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    The effect of copper content in the range of 0,01 - 0,6 wt.% on the microtexture of some Fe-Si-Al non-oriented electrical sheets containing several impurity elements was investigated. The sheets were laboratory-manufactured and industrial samples of non-oriented electrical steels, decarburized and recrystallized, before the final annealing. Using the EBSD (electron backscatter diffraction) the microtexture was determined. It was found that the microtexture of the alloys containing more copper had fewer crystal grains with easy direction of magnetization in the sheet rolling plane. It was concluded that copper has a negative influence on the magnetic properties of soft-magnetic steel sheets

    Genetic interactions between a phospholipase A2 and the Rim101 pathway components in S. cerevisiae reveal a role for this pathway in response to changes in membrane composition and shape

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    Modulating composition and shape of biological membranes is an emerging mode of regulation of cellular processes. We investigated the global effects that such perturbations have on a model eukaryotic cell. Phospholipases A2 (PLA2s), enzymes that cleave one fatty acid molecule from membrane phospholipids, exert their biological activities through affecting both membrane composition and shape. We have conducted a genome-wide analysis of cellular effects of a PLA2 in the yeast Saccharomyces cerevisiae as a model system. We demonstrate functional genetic and biochemical interactions between PLA2 activity and the Rim101 signaling pathway in S. cerevisiae. Our results suggest that the composition and/or the shape of the endosomal membrane affect the Rim101 pathway. We describe a genetically and functionally related network, consisting of components of the Rim101 pathway and the prefoldin, retromer and SWR1 complexes, and predict its functional relation to PLA2 activity in a model eukaryotic cell. This study provides a list of the players involved in the global response to changes in membrane composition and shape in a model eukaryotic cell, and further studies are needed to understand the precise molecular mechanisms connecting them

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    Abstract. Gender differences in CAD have been clearly documented, and sex hormones have been recognized to influence the risk of CAD. The cytochrome P450c17α α gene (CYP17) and the CYP19 gene influence concentrations of sex hormones. In this cross-sectional association study we tested the hypothesis whether the T/C polymorphism of the CYP17 gene and the tetranucleotide repeat (TTTA) polymorphism of the CYP19 gene are genetic markers for CAD in Caucasians. The TT genotype of the CYP17 gene polymorphism was not associated with premature CAD in men and women combined (OR 0.9; 95% CI = 0.6-1.4; P = 0.7), in men only (OR 1; 95% CI = 0.6-1.8; P = 0.7), and in women only (OR 0.8; 95% CI = 0.5-1.4; P = 0.4). The tetranucleotide repeat (TTTA) CYP19 gene polymorphism was not associated with premature CAD. Moreover, the genotypes containing the longer alleles (A6 or A7) were not associated with a lower incidence of CAD, and the genotypes containing the shorter alleles (A1 or A2) were not over-represented in the CAD patients. We may conclude that in Caucasian subjects neither the T/C CYP17 gene polymorphism nor the tetranucleotide repeat (TTTA) polymorphism of the CYP19 gene contributes to the genetic susceptibility to CAD, therefore they may not be used as genetic markers for CAD risk assessment. Gender differences in coronary artery disease (CAD) have been clearly documented, and sex hormones have been recognized to influence the risk of developing cardiovascular disease The cytochrome P450c17α gene (CYP17) encodes the cytochrome P450c17α enzyme, which is involved in the formation of precursors of testosterone and oestradiol. The T/C polymorphism of the CYP17 gene creates a recognition site for the MspA1 restriction enzyme and has been used to designate two alleles, A1 (T) and A2 (C). Subjects with the C allele have an additional Sp 1 site, which results in an increased expression of the gene The CYP19 gene encodes the enzyme aromatase (P450aro) that is crucially involved in the production of oestrogens from androgens. In men and postmenopausal women the enzyme aromatase is the main source of circulating oestrogens produced mainly peripherally from androgenic steroids, whereas in premenopausal women the ovary is the main source of circulating oestradiol Associations of the CYP17 and CYP19 polymorphisms are being extensively studied to clarify their role in hormone-related cancers (breast, endometrial, prostate and ovarian cancer), osteoporosis, and hip frac
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