Una curiosa sfilata di soldatacci mangiati dalla fame e pidocchiosi. Le illustrazioni di Alberto Martini per La secchia rapita.

The article focuses on Alberto Martini's illustrations for Alessandro Tassoni's Secchia rapita, painted from 1895 to 1935, as an example of parody in visual art. It analyzes the numerous influences in Martini's work. Martini took his inspiration from contemporary art, like for instance Beardsley, Rubino, Sattler; and from Old Masters, like Callot, Della Bella, Hogart, Fussli. But he also used models and themes from some Renaissance Italian Masters, like Antonello da Messina, Carpaccio, Leonardo, Cellini. This looks crucial in order to understand how the artist, by following Tassoni's idea to use the epic style for a parody of Tasso's poem, did the same in painting, changing the solemn Renaissance models into a mock-heroic style of art

Poster Abstract: MagoNode++ - A Wake-Up-Radio-Enabled Wireless Sensor Mote for Energy-Neutral Applications

The combination of low-power design, energy harvesting and ultra-low-power wake-up radios is paving the way for perpetual operation of Wireless Sensor Networks (WSNs). In this work we present the MagoNode++, a novel WSN platform supporting energy harvesting and radio-triggered wake ups for energy- neutral applications. The MagoNode++ features an energy- harvesting subsystem composed by a light or thermoelectric harvester, a battery manager and a power manager module. It further integrates a state-of-the-art RF Wake-Up Receiver (WUR) that enables low-latency asynchronous communication, virtually eliminating idle listening at the main transceiver. Experimental results show that the MagoNode++ consumes only 2.8uA with the WUR in idle listening and the rest of the platform in sleep state, making it suitable for energy-constrained WSN scenarios and for energy-neutral applications

Aromatase inhibitors, efficacy and metabolic risk in the treatment of postmenopausal women with early breast cancer

The third-generation aromatase inhibitors (AIs), letrozole, anastrozole and exemestane, are becoming the first choice endocrine drugs for post-menopausal women with breast cancer, since they present greater efficacy when compared with tamoxifen in both adjuvant and metastatic setting. In particular, several large and well designed trials have suggested an important role for AIs in the adjuvant treatment of postmenopausal women with estrogen-receptor positive breast cancer either in the upfront, sequential or extended adjuvant mode. Overall, AIs are associated with a small but significant improvement in disease free survival. The expanding use of AIs in the treatment of early breast cancer means that individual patients will be exposed to the agents for longer durations, making it increasingly important to establish their long-term safety. This review focused on the effects of AIs on bone metabolism, serum lipids and cardiovascular risk. AIs have adverse effects on bone turnover with a reduction of bone mineral density and an increase in the rate of fragility fractures. With respect to tamoxifen AIs present lower thrombotic risk and a less favorable impact on lipid profile, whereas the true effects on cardiovascular risk still remain to be clarified. An adequate monitoring of bone mineral density (BMD) and lipid profile could be recommended for post-menopausal women candidate to AIs

EYES - Energy Efficient Sensor Networks

The EYES project (IST-2001-34734) is a three years European research project on self-organizing and collaborative energy-efficient sensor networks. It will address the convergence of distributed information processing, wireless communications, and mobile computing. The goal of the project is to develop the architecture and the technology which enables the creation of a new generation of sensors that can effectively network together so as to provide a flexible platform for the support of a large variety of mobile sensor network applications. This document gives an overview of the EYES project

Is there still a place for docetaxel rechallenge in prostate cancer?

Three-weekly docetaxel plus prednisone is the standard first-line cytotoxic treatment for patients with metastatic castrate-resistant prostate cancer (mCRPC). Today, several new treatment options are available for patients with tumor progression after first-line docetaxel: Abiraterone, enzalutamide, cabazitaxel, sipuleucel-T immunotherapy, and the radionuclide radium-223. However, despite the evolving scenario in CRPC treatment, the optimal sequencing of the innovative therapies remains unclear. The reintroduction of docetaxel at the occurrence of disease progression after a drug holiday (docetaxel rechallenge) was often proposed, and this chemotherapeutic agent showed to maintain antitumor activity in mCRPC patients. Docetaxel rechallenge may still constitute a valid treatment option mainly for patients with favorable response to first-line docetaxel, at least > 3 mo progression-free interval, age less than 75 years, good performance status, and acceptable docetaxel toxicity. The risk of cumulative toxicity must be evaluated, since sensory neuropathy, nail disorders and fatigue might occur on docetaxel rechallenge

A channel aware adaptive modem for underwater acoustic communications

Acoustic underwater channels are very challenging, because of limited bandwidth, long propagation delays, extended multipath, severe attenuation, rapid time variation and large Doppler shifts. A plethora of underwater communication techniques have been developed for dealing with such a complexity, mostly tailoring specific applications scenarios which can not be considered as one-size-fits-all solutions. Indeed, the design of environment-specific solutions is especially critical for modulations with high spectral efficiency, which are very sensitive to channel characteristics. In this paper, we design and implement a software-defined modem able to dynamically estimate the acoustic channel conditions, tune the parameters of a OFDM modulator as a function of the environment, or switch to a more robust JANUS/FSK modulator in case of harsh propagation conditions. The temporal variability of the channel behavior is summarized in terms of maximum delay spread and Doppler spread. We present a very efficient solution for deriving these parameters and discuss the limit conditions under which the OFDM modulator can work. In such scenarios, we also calibrate the prefix length and the number of sub-carriers for limiting the inter-symbol interference and signal distortions due to the Doppler effect. We validate our estimation and adaptation techniques by using both a custom-made simulator for time-varying underwater channels and the well-known Watermark simulator, as well as real in field experiments. Our results show that, for many practical cases, a dynamic adjustment of the prefix length and number of sub-carriers may enable the utilization of OFDM modulations in underwater communications, while in harsher environments JANUS can be used as a fall-back modulation