HIGH RESOLUTION SPECTROSCOPIC STUDIES OF 1-(1-NAPHTHYL) ETHYLAMINE IN S0S_{0} AND S1S_{1}: EXPLORING THE DEPENDENCE OF CIRCULAR DICHROISM ON CONFORMATIONAL STRUCTURE

Author Institution: Optical Technology Division, National Institute of TechnologyClassical and/or quantum mechanical models developed for isolated molecules are commonly used to extract structural information from optical activity measurements dispite the lack of experimental data for validation of these models. Rotationally-resolved gas phase spectra of the prototypical chiral molecule, 1-(1-Naphthyl) ethylamine (NEA), and its amine deuterated forms have been obtained in the microwave and ultraviolet regions to provide such data. The results of the microwave study indicate that only one conformational form exists under jet-cooled conditions. The substituted atom positions and dipole moment orientation are used to identify the structural configuration of the attached chiral group from amoung nine possible ab initio forms ($B3LYP/6-31G^{\ast}$). The $S_{1}$ inertial parameters and transition moment orientation from the UV data of the band origin at 314 nm have been used to test excited state predictions from ab initio models. CD spectra have also been calculated for the four lowest energy conformations and compared with the observed CD spectrum of (S)-NEA in cyclohexane. These results provide rigorous benchmark data and further elucidate the importance of conformational structure for determinations of absolute stereochemistry from CD spectra. The current progress on gas phase CD measurements will also be discussed

Linearly polarized second harmonic generation microscopy reveals chirality

In optics, chirality is typically associated with circularly polarized light. Here we present a novel way to detect the handedness of chiral materials with linearly polarized light. We performed Second Harmonic Generation (SHG) microscopy on G-shaped planar chiral nanostructures made of gold. The SHG response originates in distinctive hotspots, whose arrangement is dependent of the handedness. These results uncover new directions for studying chirality in artificial materials. (C) 2010 Optical Society of Americ