Les complications de l'hystérectomie vaginale

CAEN-BU Médecine pharmacie (141182102) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Complications et résultats à long terme des cures de prolapsus par voie vaginale avec prothèses

CAEN-BU Médecine pharmacie (141182102) / SudocSudocFranceF

Cure chirurgicale de cystocèle par pose d'une prothèse synthétique par double voie transobturatrice (étude de 123 cas)

CAEN-BU Médecine pharmacie (141182102) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Chirurgie vaginale du prolapsus génital (techniques, résultats anatomiques et fonctionnels à 2 ans d'une série continue de 108 patientes opérées par la triple opération périnéale avec prothèses)

CAEN-BU Médecine pharmacie (141182102) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Faisabilité de la promontofixation par voie coelioscopique (à propos de 56 cas)

CAEN-BU Médecine pharmacie (141182102) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

La voie transobturatrice, une nouvelle technique de cure chirurgicale de l'incontinence urinaire d'effort de la femme (étude de 70 cas)

CAEN-BU Médecine pharmacie (141182102) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Epidemiology of Endometriosis in France: A Large, Nation-Wide Study Based on Hospital Discharge Data

We aimed to assess the prevalence of hospitalization for endometriosis in the general population in France and in each French region and to describe temporal trends, rehospitalization rates, and prevalence of the different types of endometriosis. The analyses were carried out on French hospital discharge data and covered the period 2008–2012 and a population of 14,239,197 women of childbearing age. In this population, the prevalence of hospitalization for endometriosis was 0.9%, ranging from 0.4% to 1.6% between regions. Endometriosis affected 1.5% of hospitalized women of childbearing age, ranging from 1.0% to 2.4% between regions. The number of patients hospitalized for endometriosis significantly increased over the study period (p<0.01). Of these, 4.2% were rehospitalized at least once at one year: ranging from 2.7% to 6.3% between regions. The cumulative rehospitalization rate at 3 years was 6.9%. The types of endometriosis according to the procedures performed were as follows: ovarian (40–50%), peritoneal (20–30%), intestinal (10–20%), and ureteral or bladder (<10%), with significant differences between regions. This is the first detailed epidemiological study of endometriosis in France. Further studies are needed to assess the reasons for the increasing prevalence of endometriosis and for the significant differences in regional prevalence of this disease

Expression of estrogen receptors in the pelvic floor of pre- and post-menopausal women presenting pelvic organ prolapse

The precise role of estrogen in the pathogenesis of pelvic organ prolapse (POP) is still unclear, while the results concerning the effect of selective estrogen receptor modulators on pelvic organ prolapse are contradictory. Our aim was to test whether alteration in the expression of estrogen receptors in the pelvic floor of preand post-menopausal women is related to genital prolapse status. The mRNA levels of ER&lt;i&gt;&amp;#945;&lt;/i&gt; and ER&lt;i&gt;&amp;#946;&lt;/i&gt; in 60 biopsy specimens were measured. Significantly higher expression of ER&lt;i&gt;&amp;#945;&lt;/i&gt; and higher ER&lt;i&gt;&amp;#945;&lt;/i&gt;/ER&lt;i&gt;&amp;#946;&lt;/i&gt; ratio were demonstrated in post-menopausal women compared to pre-menopausal women. Higher expression of ER&lt;i&gt;&amp;#945;&lt;/i&gt; and higher ER&lt;i&gt;&amp;#945;&lt;/i&gt;/ER&lt;i&gt;&amp;#946;&lt;/i&gt; ratio were detected in all studied groups with POP, thus it did not reach significance in the post-menopausal group. Pre-menopausal and post-menopausal women presenting pelvic organ prolapse had no difference in the ER&lt;i&gt;&amp;alpha;&lt;/i&gt; expression. Our preliminary study may indicate that pelvic organ prolapse is associated with higher expression of ER&lt;i&gt;&amp;#945;&lt;/i&gt;/ER&lt;i&gt;&amp;#946;&lt;/i&gt; in the pelvic floor of both pre- and post-menopausal women; thus not reaching statistical significance in the post-menopausal women was probably due to the group&amp;#8217;s size. We believe that the inevitable changes in the estrogen receptor expression over women&amp;#8217;s different lifetimes may affect the risk of genital prolapse progression, and might contribute to the further search for appropriate selective estrogen receptor modulators as a treatment for women with pelvic organ prolapse. (&lt;i&gt;Folia Histochemica et Cytobiologica 2011; Vol. 49, No. 3, pp. 521&amp;#8211;527&lt;/i&gt;