Estimated mortality on HIV treatment among active patients and patients lost to follow-up in 4 provinces of Zambia: Findings from a multistage sampling-based survey - Fig 2

<p><b>Naïve and revised mortality estimates among all antiretroviral therapy (ART) users (<i>N</i> = 165,464) and new ART users (<i>N</i> = 49, 129) in (A) cumulative incidence of mortality among all ART users.</b> (B) Cumulative incidence of mortality among new ART users. (C) Mortality rate among all ART users. (D) Mortality rate among new ART users. PY, person-year.</p

Study population demographics.

<p>IQR – interquartile range; TB – tuberculosis; PTB – pulmonary TB; EPTB - extrapulmonary TB; CNS – central nervous system.</p>a<p>Pearson chi-squared test.</p>b<p>Admission diagnosis could not be gathered from 14 admissions.</p

Proportion of patients who died after starting antiretroviral therapy (ART) by engagement status, with left truncation for individuals on ART before the study observation period (<i>N</i> = 165,464).

<p>Lost was defined as having been more than 90 days late for a visit, and late was defined as being 15–90 days late for a visit.</p

Duration on antiretroviral therapy (ART) and contribution to overall mortality among all ART users.

<p>Duration on antiretroviral therapy (ART) and contribution to overall mortality among all ART users.</p

TB prevalence in different patient groups stratified by HIV status (HIV status was available for 858/900 study participants).

<p>TB prevalence in different patient groups stratified by HIV status (HIV status was available for 858/900 study participants).</p

Predictors of mortality among all antiretroviral therapy (ART) users and new ART users.

<p>Predictors of mortality among all antiretroviral therapy (ART) users and new ART users.</p

Burden of pulmonary TB and admission diagnosis co-morbidities with HIV, NCDs and CDs.

<p>Data are n TB positive/n tested (%) [95% CI], Odds Ratios (ORs) and associated confidence intervals (CIs) from binary logistic regression analysis.</p>a<p>Multivariate analysis was controlled for the effects of Age and HIV.</p>b<p>Age was analysed as a continuous variable but is displayed as grouped to illustrate the distribution.</p>c<p>Three TB culture negative patients were represented in multiple NCD diagnosis categories.</p>d<p>Two TB culture negative patients were represented in multiple CD diagnosis categories.</p

Patient Recruitment Summary.

<p>Patient Recruitment Summary.</p

Modified Lorenz curve depicting excess mortality in new antiretroviral therapy (ART) users (<i>N</i> = 49,129).

<p>Modified Lorenz curve depicting excess mortality in new antiretroviral therapy (ART) users (<i>N</i> = 49,129).</p

Descriptive characteristics of the study cohort.

<p>Descriptive characteristics of the study cohort.</p