3,954 research outputs found
Which Triggers Produce the Most Erosive, Frequent, and Longest Runout Turbidity Currents on Deltas?
Subaerial rivers and turbidity currents are the two most voluminous sediment transport processes on our planet, and it is important to understand how they are linked offshore from river mouths. Previously, it was thought that slope failures or direct plunging of river floodwater (hyperpycnal flow) dominated the triggering of turbidity currents on delta fronts. Here we reanalyze the most detailed timeâlapse monitoring yet of a submerged delta; comprising 93 surveys of the Squamish Delta in British Columbia, Canada. We show that most turbidity currents are triggered by settling of sediment from dilute surface river plumes, rather than landslides or hyperpycnal flows. Turbidity currents triggered by settling plumes occur frequently, run out as far as landslideâtriggered events, and cause the greatest changes to delta and lobe morphology. For the first time, we show that settling from surface plumes can dominate the triggering of hazardous submarine flows and offshore sediment fluxes
Individual Nurse Productivity in Preparing Patients for Discharge Is Associated with Patient Likelihood of 30-Day Return to Hospital
Objective:
Applied to value-based health care, the economic term âindividual productivityâ refers to the quality of an outcome attributable through a care process to an individual clinician. This study aimed to (1) estimate and describe the discharge preparation productivities of individual acute care nurses and (2) examine the association between the discharge preparation productivity of the discharging nurse and the patientâs likelihood of a 30-day return to hospital [readmission and emergency department (ED) visits]. Research Design:
Secondary analysis of patient-nurse data from a cluster-randomized multisite study of patient discharge readiness and readmission. Patients reported discharge readiness scores; postdischarge outcomes and other variables were extracted from electronic health records. Using the structure-process-outcomes model, we viewed patient readiness for hospital discharge as a proximal outcome of the discharge preparation process and used it to measure nurse productivity in discharge preparation. We viewed hospital return as a distal outcome sensitive to discharge preparation care. Multilevel regression analyses used a split-sample approach and adjusted for patient characteristics. Subjects:
A total 522 nurses and 29,986 adult (18+ây) patients discharged to home from 31 geographically diverse medical-surgical units between June 15, 2015 and November 30, 2016. Measures:
Patient discharge readiness was measured using the 8-item short form of Readiness for Hospital Discharge Scale (RHDS). A 30-day hospital return was a categorical variable for an inpatient readmission or an ED visit, versus no hospital return. Results:
Variability in individual nurse productivity explained 9.07% of variance in patient discharge readiness scores. Nurse productivity was negatively associated with the likelihood of a readmission (â0.48 absolute percentage points, P\u3c0.001) and an ED visit (â0.29 absolute percentage points, P=0.042). Conclusions:
Variability in individual clinician productivity can have implications for acute care quality patient outcomes
Non-Markovian Stochastic Resonance: three state model of ion channel gating
Stochastic Resonance in single voltage-dependent ion channels is investigated
within a three state non-Markovian modeling of the ion channel conformational
dynamics. In contrast to a two-state description one assumes the presence of an
additional closed state for the ion channel which mimics the manifold of
voltage-independent closed subconformations (inactivated ``state''). The
conformational transition into the open state occurs through a domain of
voltage-dependent closed subconformations (closed ``state''). At distinct
variance with a standard two-state or also three-state Markovian approach, the
inactivated state is characterized by a broad, non-exponential probability
distribution of corresponding residence times. The linear response to a
periodic voltage signal is determined for arbitrary distributions of the
channel's recovery times. Analytical results are obtained for the spectral
amplification of the applied signal and the corresponding signal-to-noise
ratio. Alternatively, these results are also derived by use of a corresponding
two-state non-Markovian theory which is based on driven integral renewal
equations [I. Goychuk and P. Hanggi, Phys. Rev. E 69, 021104 (2004)]. The
non-Markovian features of stochastic resonance are studied for a power law
distribution of the residence time-intervals in the inactivated state which
exhibits a large variance. A comparison with the case of bi-exponentially
distributed residence times possessing the same mean value, i.e. a simplest
non-Markovian two-state description, is also presented
Seminoma of Testis Masquerading as Orchitis in an Adult with Paraplegia: Proposed Measures to Avoid Delay in Diagnosing Testicular Tumours in Spinal Cord Injury Patients
Orchitis is common in adult male spinal cord injury (SCI) patients and, therefore, both health professionals and SCI patients themselves tend to attribute testicular swelling to orchitis, with a consequent potential delay in the diagnosis of testicular tumours. A 37-year-old man with paraplegia developed swelling of the right testis. With a presumptive diagnosis of acute bacterial orchitis, he was prescribed ciprofloxacin while awaiting an ultrasound scan. Ultrasound examination of the testis 4 weeks later showed a moderate hydrocele, enlargement and altered echogenicity of both the epididymis and testis, and features of mass-like lesions within the substance of the testis. As these changes might merely have represented a partly treated infection, a follow-up scan was carried out 2 weeks later, which revealed a lobulated mass of mixed echogenicity within the testis and a focal area of increased echogenicity indicative of calcification. A radical orchidectomy performed 19 days later revealed a seminoma. To prevent delay in the diagnosis of testicular tumours in SCI patients, we propose the following measures: (1) patients who develop swelling of the testis should consult a physician as soon as possible for clinical examination; blind antibiotic therapy should be avoided if possible; (2) if clinical examination reveals a hard swelling of the testis and the typical features of acute urinary infection are absent, an ultrasound scan of the scrotum should be performed as soon as possible; (3) in patients with equivocal ultrasound findings, ultrasound-guided, fine-needle aspiration cytology may allow an early diagnosis of testicular malignancy; (4) education of SCI patients and their caregivers is needed to implement these recommendations
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