785 research outputs found

    Bonus computations

    Get PDF

    Some Difficulties in Percentages

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    Book Department

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    Where should livestock graze? Integrated modeling and optimization to guide grazing management in the Cañete basin, Peru

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    Integrated watershed management allows decision-makers to balance competing objectives, for example agricultural production and protection of water resources. Here, we developed a spatially-explicit approach to support such management in the Cañete watershed, Peru. We modeled the effect of grazing management on three services – livestock production, erosion control, and baseflow provision – and used an optimization routine to simulate landscapes providing the highest level of services. Over the entire watershed, there was a trade-off between livestock productivity and hydrologic services and we identified locations that minimized this trade-off for a given set of preferences. Given the knowledge gaps in ecohydrology and practical constraints not represented in the optimizer, we assessed the robustness of spatial recommendations, i.e. revealing areas most often selected by the optimizer. We conclude with a discussion of the practical decisions involved in using optimization frameworks to inform watershed management programs, and the research needs to better inform the design of such programs

    Ramanujan sums for signal processing of low frequency noise

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    An aperiodic (low frequency) spectrum may originate from the error term in the mean value of an arithmetical function such as M\"obius function or Mangoldt function, which are coding sequences for prime numbers. In the discrete Fourier transform the analyzing wave is periodic and not well suited to represent the low frequency regime. In place we introduce a new signal processing tool based on the Ramanujan sums c_q(n), well adapted to the analysis of arithmetical sequences with many resonances p/q. The sums are quasi-periodic versus the time n of the resonance and aperiodic versus the order q of the resonance. New results arise from the use of this Ramanujan-Fourier transform (RFT) in the context of arithmetical and experimental signalsComment: 11 pages in IOP style, 14 figures, 2 tables, 16 reference

    Electronic and optical properties of electromigrated molecular junctions

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    Electromigrated nanoscale junctions have proven very useful for studying electronic transport at the single-molecule scale. However, confirming that conduction is through precisely the molecule of interest and not some contaminant or metal nanoparticle has remained a persistent challenge, typically requiring a statistical analysis of many devices. We review how transport mechanisms in both purely electronic and optical measurements can be used to infer information about the nanoscale junction configuration. The electronic response to optical excitation is particularly revealing. We briefly discuss surface-enhanced Raman spectroscopy on such junctions, and present new results showing that currents due to optical rectification can provide a means of estimating the local electric field at the junction due to illumination.Comment: 19 pages, 8 figures, invited paper for forthcoming special issue of Journal of Physics: Condensed Matter. For other related papers, see http://www.ruf.rice.edu/~natelson/publications.htm

    Impaired Ethanol-Induced Sensitization and Decreased Cannabinoid Receptor-1 in a Model of Posttraumatic Stress Disorder

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    Background and Purpose Impaired striatal neuroplasticity may underlie increased alcoholism documented in those with posttraumatic stress disorder (PTSD). Cannabinoid receptor-1 (CB1) is sensitive to the effects of ethanol (EtOH) and traumatic stress, and is a critical regulator of striatal plasticity. To investigate CB1 involvement in the PTSD-alcohol interaction, this study measured the effects of traumatic stress using a model of PTSD, mouse single-prolonged stress (mSPS), on EtOH-induced locomotor sensitization and striatal CB1 levels. Methods Mice were exposed to mSPS, which includes: 2-h restraint, 10-min group forced swim, 15-min exposure to rat bedding odor, and diethyl ether exposure until unconsciousness or control conditions. Seven days following mSPS exposure, the locomotor sensitizing effects of EtOH were assessed. CB1, post-synaptic density-95 (PSD95), and dopamine-2 receptor (D2) protein levels were then quantified in the dorsal striatum using standard immunoblotting techniques. Results Mice exposed to mSPS-EtOH demonstrated impaired EtOH-induced locomotor sensitization compared to Control-EtOH mice, which was accompanied by reduced striatal CB1 levels. EtOH increased striatal PSD95 in control and mSPS-exposed mice. Additionally, mSPS-Saline exposure increased striatal PSD95 and decreased D2 protein expression, with mSPS-EtOH exposure alleviating these changes. Conclusions These data indicate that the mSPS model of PTSD blunts the behavioral sensitizing effects of EtOH, a response that suggests impaired striatal neuroplasticity. Additionally, this study demonstrates that mice exposed to mSPS and repeated EtOH exposure decreases CB1 in the striatum, providing a mechanism of interest for understanding the effects of EtOH following severe, multimodal stress exposure

    A way to increase the bit ratein ionospheric radio links

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    The aim of this paper is to present a high data rate transmission system through the ionospheric channel in the HF-band (3-30 MHz). The applications expected in this study are image transmitting and real-time videoconferencing. Very high rates are required compared to the standard modems. Therefore, an array processing is performed with a set of antennas whose spatial response differs from one another arranged in a circular array or in a collocated sensor. Synchronization (Zero Crossing Detector) and source separation (LMS algorithm) resort to classical well-tested techniques involving training sequences. Experimental results are presented for both antenna configurations. These techniques improve data rate, reaching 20 kbits/s within the 6 kHz bandwidth (QAM 64) without coding or interleaving

    N-cadherin and β1-integrins cooperate during the development of the enteric nervous system

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    AbstractCell adhesion controls various embryonic morphogenetic processes, including the development of the enteric nervous system (ENS). Ablation of β1-integrin (β1−/−) expression in enteric neural crest cells (ENCC) in mice leads to major alterations in the ENS structure caused by reduced migration and increased aggregation properties of ENCC during gut colonization, which gives rise to a Hirschsprung's disease-like phenotype.In the present study, we examined the role of N-cadherin in ENS development and the interplay with β1 integrins during this process. The Ht–PA–Cre mouse model was used to target gene disruption of N-cadherin and β1 integrin in migratory NCC and to produce single- and double-conditional mutants for these two types of adhesion receptors.Double mutation of N-cadherin and β1 integrin led to embryonic lethality with severe defects in ENS development. N-cadherin-null (Ncad−/−) ENCC exhibited a delayed colonization in the developing gut at E12.5, although this was to a lesser extent than in β1−/− mutants. This delay of Ncad−/− ENCC migration was recovered at later stages of development. The double Ncad−/−; β1−/− mutant ENCC failed to colonize the distal part of the gut and there was more severe aganglionosis in the proximal hindgut than in the single mutants for N-cadherin or β1-integrin. This was due to an altered speed of locomotion and directionality in the gut wall. The abnormal aggregation defect of ENCC and the disorganized ganglia network in the β1−/− mutant was not observed in the double mutant. This indicates that N-cadherin enhances the effect of the β1−integrin mutation and demonstrates cooperation between these two adhesion receptors during ENS ontogenesis.In conclusion, our data reveal that N-cadherin is not essential for ENS development but it does modulate the modes of ENCC migration and acts in concert with β1−integrin to control the proper development of the ENS
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