Climate Change and Greenhouse Gas Awareness Study

This study falls within the enhancing awareness and understanding theme of the National Climate Change Strategy. It was conducted by Agriculture and Agri-Food Canada in January/February 2001 and involved 1,643 farming operation, feeder cattle, dairy cattle, hogs and poultry producers. The purpose of this study is to assess producers' level of awareness of climate change and greenhouse gas (GHG) emissions as well as their understanding of the role of agriculture in the emissions of GHG. This study also establishes a baseline measurement that will be used to evaluate the success of the awareness and public education effort regarding climate change and GHG.climate change, greenhouse gas emissions, emission targets, kyoto protocol, national climate change process, survey, Farm Management, Research Methods/ Statistical Methods,

Killer Granzyme B Linked to N-myc- and c-myc-Dependent HSC Survival: Isn't That Comyc?

c-myc is a key regulator of hemopoietic stem cell (HSC) activity. In this issue of Cell Stem Cell, Laurenti et al. (2008) show that c-myc and N-myc control HSC survival and link this finding to the regulation of granzyme B expression

Premières initiatives d’intégration sociale des malades mentaux dans une phase de pré-désinstitutionnalisation. L’exemple de Saint-Jean-de-Dieu, 1910–1950

Cet article sur les premières initiatives d’intégration sociale des malades mentaux, dans l’exemple de l’Hôpital Saint-Jean-de-Dieu, présente la mise en place d’une phase de désinstitutionnalisation au cours des premières décennies du XXe siècle. Notre étude s’inscrit dans le courant historiographique récent qui propose une relecture de la période pré-Révolution tranquille au Québec. Nous entendons y contribuer en démontrant que les politiques, les stratégies et les pratiques des Soeurs de la Providence et des psychiatres ont mis en place un système de désinstitutionnalisation et de réintégration des patients dans leur famille dès les années 1910, soit un demi-siècle avant que ne s’amorce la première vague de désinstitutionnalisation des années 1960 orchestrée par les auteurs du rapport Bédard. This article on the first initiatives of social integration of the mentally ill, using the example of the Hôpital St-Jean-de-Dieu, explores the implementation of a period of deinstitutionalization in the early decades of the 20th century. Our study is situated in the recent historiography that offers a rereading of the period just prior to the Quiet Revolution in Quebec. We intend to contribute by demonstrating that the policies, strategies and practices of the Sisters of Providence and the psychiatrists of St-Jean-de-Dieu developed a system of deinstitutionalization that reintegrated patients into their family as early as the 1910s, half a century before the first wave of deinstitutionalization of the 1960s was orchestrated by the authors of the Bédard report

Silencing of Amyloid Precursor Protein Expression Using a New Engineered Delta Ribozyme

Alzheimer's disease (AD) etiological studies suggest that an elevation in amyloid-β peptides (Aβ) level contributes to aggregations of the peptide and subsequent development of the disease. The major constituent of these amyloid peptides is the 1 to 40–42 residue peptide (Aβ40−42) derived from amyloid protein precursor (APP). Most likely, reducing Aβ levels in the brain may block both its aggregation and neurotoxicity and would be beneficial for patients with AD. Among the several possible ways to lower Aβ accumulation in the cells, we have selectively chosen to target the primary step in the Aβ cascade, namely, to reduce APP gene expression. Toward this end, we engineered specific SOFA-HDV ribozymes, a new generation of catalytic RNA tools, to decrease APP mRNA levels. Additionally, we demonstrated that APP-ribozymes are effective at decreasing APP mRNA and protein levels as well as Aβ levels in neuronal cells. Our results could lay the groundwork for a new protective treatment for AD

The Role of Expectations in Treatment Outcome and Symptom Development in Anxiety Disorders

For more than 60 years, researchers have been interested in determining the impact of expectations on treatment outcome. Earlier studies mostly focused on two types of expectations: prognostic and process expectations. Aims: To review how four different types of expectations (prognostic, process, anxiety expectancy and anxiety sensitivity) contribute to psychotherapy outcome, and to the development of clinical disorders, especially anxiety. Conclusions: First, the role of process and prognostic expectancies in clinical disorders and psychotherapy outcome should be clarified by addressing the methodological flaws of the earlier expectancy studies. Second, studies, especially those on anxiety disorders, may benefit from evaluating the four different types of expectations to determine their relative impact on outcome, and on the development and maintenance of these disorders. Third, possible links with other clinical disorders should be further explored. Finally, expectancies should be assessed prior to treatment and after several sessions to determine the extent to which the treatment\u27s failure in modifying initial low expectancies contribute to a poor outcome