453 research outputs found

    Scaffolding for assessment success: using gradual release of responsibility to support resident transition to competency-based medical education

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    In competency-based medical education (CBME), assessment is learner-driven; learners may fail to progress if assessments are not completed. The General Internal Medicine (GIM) program at Queen’s University uses an educational technique known as scaffolding in its assessment strategy. The program applies this technique to coordinate early assessments with specific scheduled learning experiences and gradually releases the responsibility for assessment initiation to residents. Although outcomes of this innovation are still under investigation, we feel it has been valuable in supporting resident assessment capture and timely progression through stages of training.  Other residency training programs could easily implement this technique to support the transition to Competency by Design

    BeppoSAX observations of Mrk 841 and Mrk335

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    We present and discuss BeppoSAX observations of Mrk841 and Mrk335, two Seyfert 1 galaxies in which previous observations have established the presence of soft excesses. We confirm the soft excess in both sources, even if for Mrk~841 a warm absorber provides a fit almost as good as the one with a true excess. As far as the hard X-ray continuum is concerned, a Comptonization model provides a fit as good as a power law and a physically sound solution for Mrk841. For Mrk335, the Comptonization model gives a result which is somewhat better on statistical ground, but rather problematic on physical ground. The most interesting results regard the reprocessing components. For Mrk841 we find a very large reflection continuum but an almost normal iron line equivalent width even if, within the errors, a solution in which both components are a factor ~2 larger than expected for an accretion disc is still marginally acceptable. If this is the case, an anisotropy of the primary emission seems the best explanation. On the contrary, in Mrk335 we find a very large iron line EW but a reflection component not accordingly large. In this case, the best solution seems to be in terms of reflection from an ionized disc.Comment: Accepted for publication in A&

    Effect of a high forage: Concentrate ratio on milk yield, blood parameters and oxidative status in lactating cows

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    A feeding strategy that requires a forage: concentrate ratio equal to 70: 30, with at least five different herbs in the forage and the use of silages prohibited, has recently been introduced in Italy. Despite the benefits in terms of human health (lower ω6: ω3 ratio, higher conjugated linoleic acid level) of the obtained milk, little information regarding the possible effects on cows' health is available. The aim of this study was to evaluate the effects of such a feeding strategy in dairy cows (90 days in milk at the beginning of the trial) on milk yield and composition, and blood metabolic profile, including the evaluation of oxidative stress. The proposed feeding strategy, compared with a semi-intensive strategy, resulted in an improvement of animal oxidative status (lower levels of reactive oxygen metabolites, higher levels of antioxidant potential and anti-reactive oxygen metabolites) and a significant increase of milk urea only in the first part of the trial. No differences in milk yield and composition were detected throughout the trial

    Determination of the yield radius and yield stress in 2198-T3 aluminum alloy by means of the dual-scale instrumented indentation test

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    A new dual-scale instrumented indentation test (DualS-IIT) methodology is here proposed to determine the yield stress (in a tensile-like sense). The methodology involves measuring the bulk yield radius, as defined by the expansion cavity model (ECM), induced by a Vickers macro-indentation in a medium plane cross-section. The bulk yield radius is measured by means of a subsurface nano-hardness survey along the load direction in correspondence to the transition interface between the hemispherical strain hardened region and the surrounding elastic region. The methodology has been applied to an Al–Li (A2198-T3) alloy and a yield stress of 297 MPa has been measured (in agreement with a tensile test); moreover, anomalous plastic deformation behaviour has appeared under indentation. The combination of macro- and nano-indentation tests in one single experiment, as in the proposed methodology, offers a unique experimental basis to directly correlate the mechanical properties of a material at two different scales, which at present is an open issue in the research on indentation

    Secondary immune-mediated thrombocytopenia in dogs naturally infected by Leishmania infantum.

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    Forty-four dogs naturally infected by Leishmania infantum were divided into two groups: 20 thrombocytopenic dogs with fewer than 150 x 10(9) platelets/l, and 24 non-thrombocytopenic dogs with more than 200 x 10(9) platelets/l. Ten clinically healthy dogs were used as controls. A haematological profile was obtained and the dogs' serum was used to assess the presence of platelet-binding IgM and IgG antibodies using a flow cytometry technique. Nineteen of the 20 thrombocytopenic dogs, and 13 of the 24 non-thrombocytopenic dogs had detectable levels of platelet-binding immunoglobulins, but none of the control dogs did so. The differences were significantly different for both IgM and IgG platelet-binding antibodies

    Higher forage:concentrate ratio and space availability may favor positive behaviors in dairy cows

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    A novel livestock management system (LMS) for dairy cows mainly based on a high forage:concentrate ratio, no silage, and large outdoor paddocks, has been introduced in Italy during the last five years. It was proved that such system, further than improving the quality of milk, benefits the health status of cows. The goal of the present research was to compare the behavioral responses of a group of animals kept with the LMS and outdoor paddocks of 200 m2, and cows reared in a traditional semi-intensive manner and outdoor paddocks of 100 m2. The study was carried out on Italian Friesian cows analyzing the feeding and social behaviors and the locomotor activity. The statistical analysis of locomotor activity showed that the HFC group spent lower time lying down and standing and higher time walking; they also showed a longer rumination time and spent less time drinking. Furthermore, the HFC group displayed longer allogrooming and social rubbing times. Results suggest that the novel LMS could be the basis for an improvement of the cows' welfare

    Effect of colostrum and milk on small intestine expression of AQP4 and AQP5 in newborn buffalo calves.

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    Functional studies indicate differences in newborn gastrointestinal morphology and physiology after a meal. Both water and solutes transfer across the intestinal epithelial membrane appear to occur via aquaporins (AQPs). Given that the physiological roles of AQP4 and AQP5 in the developing intestine have not been fully established, the objective of this investigation was to determine their distribution, expression and respective mRNA in the small intestine of colostrums-suckling buffalo calves by using immunohistochemistry, Western blot, and reverse transcriptase-PCR analysis. Results showed different tissue distribution between AQP4 and AQP5 with the presence of the former along the enteric neurons and the latter in the endocrine cells. Moreover, their expression levels were high in the ileum of colostrum-suckling buffalo calves. The data present a link between feeding, intestinal development and water homeostasis, suggesting the involvement of these channel proteins in intestinal permeability and fluid secretion/absorption during this stage of development after birth

    Cambios en la cobertura vegetal y mapeo de un área protegida del NO argentino

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    Pero, Edgardo J. I.; José Busnelli; Juan P. Juliá. 2015. “Cambios en la cobertura vegetal y mapeo de un área protegida del NO argentino”. Lilloa 52 (1). La Reserva Experimental Horco Molle (REHM) es un área protegida perteneciente a la Facultad de Ciencias Naturales e Instituto Miguel Lillo (IML) de la Universidad Nacional de Tucumán. Su vegetación original corresponde a la parte sur del Distrito de Selvas de Transición de la Provincia Fitogeográfica de Las Yungas, también llamada Selva de “Tipa” y “Pacará”. Actualmente se encuentra en un estadio de sucesión secundaria luego de una extensa historia de deforestación y utilización para cultivo. Aceñolaza (1989) hizo un primer mapeo de la vegetación de la REHM. En este trabajo se realizó un nuevo mapeo, se superpusieron ambos mapas y se identificaron los cambios producidos en la vegetación entre 1989 y 2013. En 1989 un 70 % de la superficie estaba cubierta por pastizales y bosques de Guarán (Tecoma stans) y Afata blanca (Heliocarpus popayanensis). Actualmente el 51 % está ocupado por bosques de Ligustro o Siempre verde (Ligustrum lucidum), un árbol exótico invasor, común en las Sierras de San Javier. El 74 % de los bosques de Tecoma-Heliocarpus han sido desplazados por este invasor, lo cual demuestra que una comunidad pionera nativa puede ser ocupada por especies exóticas invasoras. Se considera que T. stans es un árbol que podría haber funcionado como percha para aves, facilitando la dispersión de L. lucidum. Aquellas áreas donde existían bosques nativos en estadios más avanzados de sucesión como los de Cebil colorado (Anadenanthera colubrina) y Laurel del cerro (Cinnamomum porphyria), aún mantienen su posición y han aumentado su superficie. Los resultados del trabajo detallan el proceso de recuperación del bosque que se viene dando en la zona. Por otra parte, el mapeo actualizado sirve de base para futuros planes de manejo de la zon
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