1,976 research outputs found
On the ongoing multiple blowout in NGC 604
Several facts regarding the structure of NGC 604 are examined here. The three
main cavities, produced by the mechanical energy from massive stars which in
NGC 604 are spread over a volume of 10 pc, are shown here to be
undergoing blowout into the halo of M33. High resolution long slit spectroscopy
is used to track the impact from massive stars while HST archive data is used
to display the asymmetry of the nebula.
NGC 604 is found to be a collection of photoionized filaments and sections of
shells in direct contact with the thermalized matter ejected by massive stars.
The multiple blowout events presently drain the energy injected by massive
stars and thus the densest photoionized gas is found almost at rest and is
expected to suffer a slow evolution.Comment: 15 pages (11 text), 4 figures. To be published in Ap
Violation of Bell's inequality for Mathieu-Gauss vector modes
Vector beams display varying polarisation over planes transversal to their
direction of propagation. The variation of polarisation implies that the
electric field cannot be expressed as a product of a spatial mode and its
polarisation. This non-separability has been analysed for particular vector
beams in terms of non--quantum entanglement between the spatial and the
polarisation-degrees of freedom, and equivalently, with respect to the degree
of polarisation of light. Here we demonstrate theoretically and experimentally
that Mathieu-Gauss vector modes violate a Bell-like inequality known as the
Clauser-Horn-Shimony-Holt-Bell (CHSH-Bell) inequality. This demonstration
provides new insights into that fact that a more general class of vector modes
with elliptical symmetry also violate Bell inequalities.Comment: 8 pages, 6 figure
Correlation of diaphragm surgical findings with preoperative CT scans in ovarian cancer
Correlation of diaphragm surgical findings in ovarian cancer patients with and without diaphragm metastases with pre-operative CT diaphragm findings to assess sensitivity and specificity for diaphragm disease. Material and Methods: A retrospective study of 120 ovarian cancer patients (60 with and 60 without diaphragm metastases at surgery), FIGO Stage IIIC or IV, undergoing cytoreductive surgery at Mayo Clinic, Arizona, between January 2000 and October 2014. All patients had preoperative imaging with CT scan of abdomen and pelvis including the lower lung fields. CTs were not reviewed retrospectively. Results: Among 60 patients with diaphragm metastases, preoperative CTs were positive for diaphragm disease in 17 patients, with a sensitivity rate of 28% (CI 95%: 0.17-0.41). All 60 patients with no diaphragm metastases had negative CTs, with a specificity of 100% (CI 95%: 94.0%-100%). When analyzed by lesion size, CTs were negative in 66.7-80% of patients with diaphragm lesions ranging from 1-15 mm. There was a trend towards increased detection rate with increasing size of lesions, but it did not reach significance (p = 0.529). CT detection rate for single metastatic lesion was 18.2% (6/33) and for multiple lesions it was 25.9% (7/27). There was no difference for CT identification of right, left, or bilateral metastases (p = 0.399). The sensitivity and specificity of CT for pleural effusion was 100% (CI 95%: 72.2%-100%) and 88% (CI 95%: 76.2%- 94.4%), respectively. The area under the receiver operating characteristic (ROC) curve was 0.680 (CI 95%: 55.3%-72.2%) for CT detection of diaphragm metastases and 0.957 (CI 95%: 79.9%-95.3%) for pleural effusions. Conclusion: CT has a low sensitivity and a high specificity for the prediction of diaphragm metastases in ovarian cancer. The size, location, and number of diaphragm lesions do not significantly improve CT detection rat
Hospital Virtual: Sistema de información clínica y telecuidado de pacientes VIH/SIDA basado en tecnologías Web 2.0
Este artículo describe el desarrollo de un nuevo sistema de información clínica y telecuidado de pacientes VIH/SIDA que se encuentra implantado en rutina clínica dentro del Servicio de Enfermedades Infecciosas del Hospital Clínic de Barcelona. El proyecto surge ante la necesidad de unificar el sistema de información departamental del servicio y un sistema de telemedicina instalado en el hospital en 2004. Para ello se han diseñado e implementado nuevas bases de datos y dos sistemas específicos para uso de profesionales y pacientes. Además, se ha realizado una integración con el Sistema de Información del Hospital (HIS) permitiendo el acceso a todos los datos requeridos de los pacientes desde una única aplicación. Este nuevo sistema está al servicio de más de 70 profesionales sanitarios que realizan una media de 150 consultas al día disponiendo de información clínica de más de 8000 pacientes
Oral Ascorbic Acid and Alpha-Tocopherol to Reduce Behavioural Problems in Young Patients Affected of Fragile X Syndrome: A Randomized, Double-Blind, Placebo-Controlled Phase II Pilot Trial
Country and policy factors influencing the implementation of primary care-based alcohol screening: a comparison of Colombia, Mexico and Peru
Purification of phosphate-dependent glutaminase from isolated mitochondria of Ehrlich ascites-tumour cells
Functional characterization of a melon alcohol acyl-transferase gene family involved in the biosynthesis of ester volatiles. Identification of the crucial role of a threonine residue for enzyme activity
Volatile esters, a major class of compounds contributing to the aroma of many fruit, are synthesized by
alcohol acyl-transferases (AAT). We demonstrate here that, in Charentais melon (Cucumis melo var.
cantalupensis), AAT are encoded by a gene family of at least four members with amino acid identity ranging
from 84% (Cm-AAT1/Cm-AAT2) and 58% (Cm-AAT1/Cm-AAT3) to only 22% (Cm-AAT1/Cm-AAT4).
All encoded proteins, except Cm-AAT2, were enzymatically active upon expression in yeast and show
differential substrate preferences. Cm-AAT1 protein produces a wide range of short and long-chain acyl
esters but has strong preference for the formation of E-2-hexenyl acetate and hexyl hexanoate. Cm-AAT3
also accepts a wide range of substrates but with very strong preference for producing benzyl acetate.
Cm-AAT4 is almost exclusively devoted to the formation of acetates, with strong preference for cinnamoyl
acetate. Site directed mutagenesis demonstrated that the failure of Cm-AAT2 to produce volatile esters is
related to the presence of a 268-alanine residue instead of threonine as in all active AAT proteins. Mutating
268-A into 268-T of Cm-AAT2 restored enzyme activity, while mutating 268-T into 268-A abolished
activity of Cm-AAT1. Activities of all three proteins measured with the prefered substrates sharply increase
during fruit ripening. The expression of all Cm-AAT genes is up-regulated during ripening and inhibited in
antisense ACC oxidase melons and in fruit treated with the ethylene antagonist 1-methylcyclopropene
(1-MCP), indicating a positive regulation by ethylene. The data presented in this work suggest that the
multiplicity of AAT genes accounts for the great diversity of esters formed in melon
Factors associated with primary health care providers\u27 measurement of their patients\u27 alcohol consumption in Colombia, Mexico and Peru
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