APPLICATION OF ESSENTIAL OILS FROM TWO SPECIES OF THE RUTACEAE FAMILY AS CELLULAR OXIDATION CONTROLLER AGENT AND TRYPANOCIDAL CAPACITY

AbstractThe essential oil isolated by hydrodistillation from peel of Citrus aurantium and Swinglea glutinosa, collected from Ibagué-Province of Tolima-Colombia (South America), was analyzed by GC/MS. The major compounds identified in essential oil of S. glutinosa were germacrene-D (30.8%), β-pinene (22.6%) and sabinene (11.6%), while limonene (94.4%)was identified as the most abundant component in C. aurantium.The ability of these products and mixturesto control cellular oxidation and measure theiranti-epimastigotes of Trypanosoma cruzi activity, the protozoan Chagas transmitter,were investigated.Besides, the type ofdrug interactionbetweenessential oil mixtureswas determinedby the values ofcombination index, which indicated for all cases the existence of a strong antagonism between the mixtures prepared.According to ABTS assay, β-carotene bleaching test andprotective activityagainst erythrocytes degradationshowed that volatiles compounds have a wide spectrum as cellular oxidation controller.This is the first time, that oils of S. glutinosa and C. aurantium, have high activity against T. cruzi, in vitro; capacity that could be directly associated to the chemotype of they, one of which (Swinglea glutinosa) appears not to be found in other research.  KeywordsEssential oil composition, Citrusaurantium, Swingleaglutinosa, ABTS, Rutaceae.Â

Comprehensive investigation of fission yields by using spallation- and (p,2p)-induced fission reactions in inverse kinematics

In the last decades, measurements of spallation, fragmentation and Coulex induced fission reactions in inverse kinematics have provided valuable data to accurately investigate the fission dynamics and nuclear structure at large deformations of a large variety of stable and non-stable heavy nuclei. To go a step further, we propose now to induce fission by the use of quasi-free (p,2p) scattering reactions in inverse kinematics, which allows us to reconstruct the excitation energy of the compound fissioning system by using the four-momenta of the two outgoing protons. Therefore, this new approach might permit to correlate the excitation energy with the charge and mass distributions of the fission fragments and with the fission probabilities, given for the first time direct access to the simultaneous measurement of the fission yield dependence on temperature and fission barrier heights of exotic heavy nuclei, respectively. The first experiment based on this methodology was realized recently at the GSI/FAIR facility and a detailed description of the experimental setup is given here.Comment: 4 pages, 15th International Conference on Nuclear Data for Science and Technology (ND2022

Quasi-free (p,2p) reactions in inverse kinematics for studying the fission yield dependence on temperature

Despite the recent experimental and theoretical progress in the investigation of the nuclear fission process, a complete description still represents a challenge in nuclear physics because it is a very complex dynamical process, whose description involves the coupling between intrinsic and collective degrees of freedom, as well as different quantum-mechanical phenomena. To improve on the existing data on nuclear fission,we produce fission reactions of heavy nuclei in inverse kinematics by using quasi-free (p,2p) scattering, which induce fission through particle-hole excitations that can range from few to ten\u27s of MeV. The measurement of the four-momenta of the two outgoing protons allows to reconstruct the excitation energy of the fissioning nucleus and therefore to study the evolution of the fission yields with temperature. The realization of this kind of experiment requires a complex experimental setup, providing full isotopic identification of both fission fragments and an accurate measurement of the momenta of the two outgoing protons. This was realized recently at the GSI/FAIR facility and here some preliminary results are presented

Chocó bio-innovador y sustentable

La formulación del Plan Estratégico Regional en Ciencia, Tecnología e Innovación del departamento del Chocó (PERCTI) tiene como propósito central señalar el camino para fortalecer el desarrollo propio e intercambio de mejores prácticas en sectores claves; reconocer la formación de expertos en áreas temáticas priorizadas; fortalecer la capacitación del talento humano mediante el aprovechamiento de capacidades instaladas en el territorio; coadyuvar a la transferencia de tecnologías necesarias para impulsar el desarrollo endógeno sustentable y, por supuesto, incentivar la incorporación de conocimiento científico y tecnológico en la cotidianidad de las personas para mejorar su calidad de vida

Comprehensive investigation of fission yields by using spallation- and (p,2p)-induced fission reactions in inverse kinematics

International audienceIn the last decades, measurements of spallation, fragmentation and Coulex induced fission reactions in inverse kinematics have provided valuable data to accurately investigate the fission dynamics and nuclear structure at large deformations of a large variety of stable and non-stable heavy nuclei. To go a step further, we propose now to induce fission by the use of quasi-free (p,2p) scattering reactions in inverse kinematics, which allows us to reconstruct the excitation energy of the compound fissioning system by using the four-momenta of the two outgoing protons. Therefore, this new approach might permit to correlate the excitation energy with the charge and mass distributions of the fission fragments and with the fission probabilities, given for the first time direct access to the simultaneous measurement of the fission yield dependence on temperature and fission barrier heights of exotic heavy nuclei, respectively. The first experiment based on this methodology was realized recently at the GSI/FAIR facility and a detailed description of the experimental setup is given here

Comprehensive investigation of fission yields by using spallation- and (p,2p)-induced fission reactions in inverse kinematics

International audienceIn the last decades, measurements of spallation, fragmentation and Coulex induced fission reactions in inverse kinematics have provided valuable data to accurately investigate the fission dynamics and nuclear structure at large deformations of a large variety of stable and non-stable heavy nuclei. To go a step further, we propose now to induce fission by the use of quasi-free (p,2p) scattering reactions in inverse kinematics, which allows us to reconstruct the excitation energy of the compound fissioning system by using the four-momenta of the two outgoing protons. Therefore, this new approach might permit to correlate the excitation energy with the charge and mass distributions of the fission fragments and with the fission probabilities, given for the first time direct access to the simultaneous measurement of the fission yield dependence on temperature and fission barrier heights of exotic heavy nuclei, respectively. The first experiment based on this methodology was realized recently at the GSI/FAIR facility and a detailed description of the experimental setup is given here

Comprehensive investigation of fission yields by using spallation- and (p,2p)- induced fission reactions in inverse kinematics

In the last decades, measurements of spallation, fragmentation and Coulex induced fission reactions in inverse kinematics have provided valuable data to accurately investigate the fission dynamics and nuclear structure at large deformations of a large variety of stable and non-stable heavy nuclei. To go a step further, we propose now to induce fission by the use of quasi-free (p,2p) scattering reactions in inverse kinematics, which allows us to reconstruct the excitation energy of the compound fissioning system by using the four-momenta of the two outgoing protons. Therefore, this new approach might permit to correlate the excitation energy with the charge and mass distributions of the fission fragments and with the fission probabilities, given for the first time direct access to the simultaneous measurement of the fission yield dependence on temperature and fission barrier heights of exotic heavy nuclei, respectively. The first experiment based on this methodology was realized recently at the GSI/FAIR facility and a detailed description of the experimental setup is given here